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Volumn 123, Issue 6, 1998, Pages 993-999

Regulation and function of DNA methylation in vertebrates

Author keywords

DNA methylation; DNA methyltransferase; Gene expression; Vertebrates

Indexed keywords

CYTOSINE; TRANSCRIPTION FACTOR;

EID: 0031776221     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a022066     Document Type: Review
Times cited : (61)

References (74)
  • 1
    • 0027353343 scopus 로고
    • A chronicle of DNA methylation (1948-1975)
    • Jost, J.P. and Saluz, H.P., eds., Birkhäuser Verlag, Basel
    • Weissbach, A. (1993) A chronicle of DNA methylation (1948-1975) in DNA Methylation: Molecular Biology and Biological Significance (Jost, J.P. and Saluz, H.P., eds.) pp. 1-10, Birkhäuser Verlag, Basel
    • (1993) DNA Methylation: Molecular Biology and Biological Significance , pp. 1-10
    • Weissbach, A.1
  • 2
    • 0018418293 scopus 로고
    • Absence of cytosine methylation at CCGG and GCGC sites in the rDNA coding regions and intervening sequences of Drosophila and the rDNA of other higher insects
    • Rae, P.M. and Steele, R.E. (1979) Absence of cytosine methylation at CCGG and GCGC sites in the rDNA coding regions and intervening sequences of Drosophila and the rDNA of other higher insects. Nucleic Acids Res. 6, 2987-2995
    • (1979) Nucleic Acids Res. , vol.6 , pp. 2987-2995
    • Rae, P.M.1    Steele, R.E.2
  • 3
    • 0026552890 scopus 로고
    • DNA methylation pattern changes during development of a sea urchin
    • Fronk, J., Tank, G.A., and Langmore, J.P. (1992) DNA methylation pattern changes during development of a sea urchin. Biochem. J. 283, 751-753
    • (1992) Biochem. J. , vol.283 , pp. 751-753
    • Fronk, J.1    Tank, G.A.2    Langmore, J.P.3
  • 4
    • 0031027468 scopus 로고    scopus 로고
    • Methylation of genomes and genes at the invertebrate-vertebrate boundary
    • Tweedie, S., Charlton, J., Clark, V., and Bird, A. (1997) Methylation of genomes and genes at the invertebrate-vertebrate boundary. Mol. Cell. Biol. 17, 1469-1475
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 1469-1475
    • Tweedie, S.1    Charlton, J.2    Clark, V.3    Bird, A.4
  • 5
    • 0028940587 scopus 로고
    • Gene number, noise reduction and biological complexity
    • Bird, A.P. (1995) Gene number, noise reduction and biological complexity. Trends Genet. 11, 94-100
    • (1995) Trends Genet. , vol.11 , pp. 94-100
    • Bird, A.P.1
  • 7
    • 0019194794 scopus 로고
    • Tissue-specific DNA methylation in a cluster of rabbit β-like globin genes
    • Shen, C.-K.J. and Maniatis, T. (1980) Tissue-specific DNA methylation in a cluster of rabbit β-like globin genes. Proc. Natl. Acad. Sci. USA 77, 6634-6638
    • (1980) Proc. Natl. Acad. Sci. USA , vol.77 , pp. 6634-6638
    • Shen, C.-K.J.1    Maniatis, T.2
  • 8
    • 0030840954 scopus 로고    scopus 로고
    • Cytosine methylation and the ecology of intragenomic parasites
    • Yoder, J.A., Walsh, C.P., and Bestor, T.H. (1997) Cytosine methylation and the ecology of intragenomic parasites. Trends Genet. 13, 335-340
    • (1997) Trends Genet. , vol.13 , pp. 335-340
    • Yoder, J.A.1    Walsh, C.P.2    Bestor, T.H.3
  • 9
    • 0023663888 scopus 로고
    • Expression of a single transfected cDNA converts fibroblasts to myoblasts
    • Davis, R.L., Weintraub, H., and Lassar, A.B. (1987) Expression of a single transfected cDNA converts fibroblasts to myoblasts. Cell 51, 987-1000
    • (1987) Cell , vol.51 , pp. 987-1000
    • Davis, R.L.1    Weintraub, H.2    Lassar, A.B.3
  • 10
    • 0028804264 scopus 로고
    • Isolation of a novel cDNA that encodes a protein localized to the pre-acrosome region of spermatids
    • Aoto, H., Tsuchida, J., Nishina, Y., Nishimune, Y., Asano, A., and Tajima, S. (1995) Isolation of a novel cDNA that encodes a protein localized to the pre-acrosome region of spermatids. Eur. J. Biochem. 234, 8-15
    • (1995) Eur. J. Biochem. , vol.234 , pp. 8-15
    • Aoto, H.1    Tsuchida, J.2    Nishina, Y.3    Nishimune, Y.4    Asano, A.5    Tajima, S.6
  • 11
    • 0018860957 scopus 로고
    • Cellular differentiation, cytidine analogs and DNA methylation
    • Jones, P.A. and Taylor, S.M. (1980) Cellular differentiation, cytidine analogs and DNA methylation. Cell 20, 85-93
    • (1980) Cell , vol.20 , pp. 85-93
    • Jones, P.A.1    Taylor, S.M.2
  • 12
    • 0031568862 scopus 로고    scopus 로고
    • Genomic organization of the mouse AZ1 gene that encodes the protein localized to preacrosomes of spermatids
    • Aoto, H., Miyake, Y., Nakamura, M., and Tajima, S. (1997) Genomic organization of the mouse AZ1 gene that encodes the protein localized to preacrosomes of spermatids. Genomics 40, 138-141
    • (1997) Genomics , vol.40 , pp. 138-141
    • Aoto, H.1    Miyake, Y.2    Nakamura, M.3    Tajima, S.4
  • 13
    • 0026708177 scopus 로고
    • Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
    • Li, E., Bestor, T.H., and Jaenisch, R. (1992) Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 69, 915-926
    • (1992) Cell , vol.69 , pp. 915-926
    • Li, E.1    Bestor, T.H.2    Jaenisch, R.3
  • 14
    • 0027378582 scopus 로고
    • Role for DNA methylation in genomic imprinting
    • Li, E., Beard, C., and Jaenisch, R. (1993) Role for DNA methylation in genomic imprinting. Nature 366, 362-365
    • (1993) Nature , vol.366 , pp. 362-365
    • Li, E.1    Beard, C.2    Jaenisch, R.3
  • 15
    • 0030670449 scopus 로고    scopus 로고
    • Competition - A common motif for the imprinting mechanism?
    • Barlow, D.P. (1997) Competition - a common motif for the imprinting mechanism? EMBO J. 16, 6899-6905
    • (1997) EMBO J. , vol.16 , pp. 6899-6905
    • Barlow, D.P.1
  • 16
    • 0002641182 scopus 로고    scopus 로고
    • X-chromosome inactivation and epigenetic mechanisms
    • Russo, V.E.A., Martienssen, R.A., and Riggs, A.D., eds., Cold Spring Harbor Laboratory Press, New York
    • Riggs, A.D. and Porter, T.N. (1996) X-chromosome inactivation and epigenetic mechanisms in Epigenetic Mechanisms of Gene Regulation (Russo, V.E.A., Martienssen, R.A., and Riggs, A.D., eds.) pp. 231-248, Cold Spring Harbor Laboratory Press, New York
    • (1996) Epigenetic Mechanisms of Gene Regulation , pp. 231-248
    • Riggs, A.D.1    Porter, T.N.2
  • 17
    • 0031001346 scopus 로고    scopus 로고
    • Xist has properties of the X-chromosome inactivation centre
    • Herzing L.B.K., Romer, J.T., Horn, J.M., and Ashworth, A. (1997) Xist has properties of the X-chromosome inactivation centre. Nature 386, 272-275
    • (1997) Nature , vol.386 , pp. 272-275
    • Herzing, L.B.K.1    Romer, J.T.2    Horn, J.M.3    Ashworth, A.4
  • 18
    • 0030895047 scopus 로고    scopus 로고
    • Long-range cis effects of ectopic X-inactivation centres on a mouse autosome
    • Lee, J.T. and Jaenisch, R. (1997) Long-range cis effects of ectopic X-inactivation centres on a mouse autosome. Nature 386, 275-279
    • (1997) Nature , vol.386 , pp. 275-279
    • Lee, J.T.1    Jaenisch, R.2
  • 19
    • 0030743612 scopus 로고    scopus 로고
    • DNA methylation and imprinting: Why bother?
    • Jaenisch, R. (1997) DNA methylation and imprinting: Why bother? Trends Genet. 13, 323-329
    • (1997) Trends Genet. , vol.13 , pp. 323-329
    • Jaenisch, R.1
  • 20
    • 0029847223 scopus 로고    scopus 로고
    • Complementation of methylation deficiency in embryonic stem cells by a DNA methyltransferase minigene
    • Tucker, K.L., Talbot, D., Lee, M.A., Leonhardt, H., and Jaenisch, R. (1996) Complementation of methylation deficiency in embryonic stem cells by a DNA methyltransferase minigene. Proc. Natl. Acad. Sci. USA 93, 12920-12925
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 12920-12925
    • Tucker, K.L.1    Talbot, D.2    Lee, M.A.3    Leonhardt, H.4    Jaenisch, R.5
  • 21
    • 0030459140 scopus 로고    scopus 로고
    • The role of DNA methylation in cancer genetics and epigenetics
    • Laird, P.W. and Jaenisch, R. (1996) The role of DNA methylation in cancer genetics and epigenetics. Annu. Rev. Genet. 30, 441-464
    • (1996) Annu. Rev. Genet. , vol.30 , pp. 441-464
    • Laird, P.W.1    Jaenisch, R.2
  • 22
    • 0025945632 scopus 로고
    • DNA methylation and gene expression
    • Razin, A. and Cedar, H. (1991) DNA methylation and gene expression. Microbiol. Rev. 55, 451-458
    • (1991) Microbiol. Rev. , vol.55 , pp. 451-458
    • Razin, A.1    Cedar, H.2
  • 23
    • 0030221162 scopus 로고    scopus 로고
    • Regulated demethylation of the myoD distal enhancer during skeletal myogenesis
    • Brunk, B.P., Goldhamer, D.J., and Emerson, Jr., C.P. (1996) Regulated demethylation of the myoD distal enhancer during skeletal myogenesis. Dev. Biol. 177, 490-503
    • (1996) Dev. Biol. , vol.177 , pp. 490-503
    • Brunk, B.P.1    Goldhamer, D.J.2    Emerson Jr., C.P.3
  • 24
    • 0030744463 scopus 로고    scopus 로고
    • Methylation of an ETS site in the intron enhancer of the keratin 18 gene participates in tissue-specific repression
    • Umezawa, A., Yamamoto, H., Rhodes, K., Klemsz, M.J., Maki, R.A., and Oshima, R.G. (1997) Methylation of an ETS site in the intron enhancer of the keratin 18 gene participates in tissue-specific repression. Mol. Cell. Biol. 17, 4885-4894
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 4885-4894
    • Umezawa, A.1    Yamamoto, H.2    Rhodes, K.3    Klemsz, M.J.4    Maki, R.A.5    Oshima, R.G.6
  • 25
    • 0027342695 scopus 로고
    • Steroid hormone dependent change in DNA methylation and its significance for the activation or silencing of specific genes
    • Jost, J.P. and Saluz, H.P., eds., Birkhäuser Verlag, Basel
    • Jost, J.P. and Saluz, H.P. (1993) Steroid hormone dependent change in DNA methylation and its significance for the activation or silencing of specific genes in DNA Methylation: Molecular Biology and Biological Significance (Jost, J.P. and Saluz, H.P., eds.) pp. 425-451, Birkhäuser Verlag, Basel
    • (1993) DNA Methylation: Molecular Biology and Biological Significance , pp. 425-451
    • Jost, J.P.1    Saluz, H.P.2
  • 26
    • 0027535235 scopus 로고
    • Effects of DNA methylation on DNA-binding proteins and gene expression
    • Tate, P.H. and Bird, A.P. (1993) Effects of DNA methylation on DNA-binding proteins and gene expression. Curr. Opin. Genet. Dev. 3, 226-231
    • (1993) Curr. Opin. Genet. Dev. , vol.3 , pp. 226-231
    • Tate, P.H.1    Bird, A.P.2
  • 27
    • 0024121584 scopus 로고
    • Cytosine methylation does not affect binding of transcription factor Sp1
    • Harrington, M.A., Jones, P.A., Imagawa, M., and Karin, M. (1988) Cytosine methylation does not affect binding of transcription factor Sp1. Proc. Natl. Acad. Sci. USA 85, 2066-2070
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 2066-2070
    • Harrington, M.A.1    Jones, P.A.2    Imagawa, M.3    Karin, M.4
  • 28
    • 0027353988 scopus 로고
    • Effect of DNA methylation on the binding of vertebrate and plant proteins to DNA
    • Jost, J.P. and Saluz, H.P., eds., Birkhäuser Verlag, Basel
    • Ehrlich, M. and Ehrlich, K.C. (1993) Effect of DNA methylation on the binding of vertebrate and plant proteins to DNA in DNA Methylation: Molecular Biology and Biological Significance (Jost, J.P. and Saluz, H.P., eds.) pp. 145-168, Birkhäuser Verlag, Basel
    • (1993) DNA Methylation: Molecular Biology and Biological Significance , pp. 145-168
    • Ehrlich, M.1    Ehrlich, K.C.2
  • 29
    • 0344630574 scopus 로고
    • Chromatin structure is required to block transcription of the methylated herpes simplex virus thymidine kinase gene
    • Buschhausen, G., Wittig, B., Graessmann, M., and Graessmann, A. (1987) Chromatin structure is required to block transcription of the methylated herpes simplex virus thymidine kinase gene. Proc. Natl. Acad. Sci. USA 84, 1177-1181
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 1177-1181
    • Buschhausen, G.1    Wittig, B.2    Graessmann, M.3    Graessmann, A.4
  • 30
    • 0027753855 scopus 로고
    • A nuclear protein with enhanced binding to methylated Sp1 sites in the AIDS virus promoter
    • Joel, P., Shao, W., and Pratt, K. (1993) A nuclear protein with enhanced binding to methylated Sp1 sites in the AIDS virus promoter. Nucleic Acids Res. 21, 5786-5793
    • (1993) Nucleic Acids Res. , vol.21 , pp. 5786-5793
    • Joel, P.1    Shao, W.2    Pratt, K.3
  • 31
    • 2642603953 scopus 로고
    • Identification of two novel mouse nuclear proteins that bind selectively to a methylated c-Myc recognizing sequence
    • Suetake, I., Tajima, S., and Asano, A. (1993) Identification of two novel mouse nuclear proteins that bind selectively to a methylated c-Myc recognizing sequence. Nucleic Acids Res. 118, 244-249
    • (1993) Nucleic Acids Res. , vol.118 , pp. 244-249
    • Suetake, I.1    Tajima, S.2    Asano, A.3
  • 32
    • 0029123669 scopus 로고
    • A novel DNA binding protein that recognizes the methylated c-Myc binding motif
    • Suetake, I., Tajima, S., and Asano, A. (1995) A novel DNA binding protein that recognizes the methylated c-Myc binding motif. J. Biochem. 118, 244-249
    • (1995) J. Biochem. , vol.118 , pp. 244-249
    • Suetake, I.1    Tajima, S.2    Asano, A.3
  • 33
    • 0031574073 scopus 로고    scopus 로고
    • The methylated DNA binding protein-2-H1 (MDBP-2-H1) consists of histone H1 subtypes which are truncated at the C-terminus
    • Schwarz, S., Hess, D., and Jost, J.P. (1997) The methylated DNA binding protein-2-H1 (MDBP-2-H1) consists of histone H1 subtypes which are truncated at the C-terminus. Nucleic Acids Res. 25, 5052-5056
    • (1997) Nucleic Acids Res. , vol.25 , pp. 5052-5056
    • Schwarz, S.1    Hess, D.2    Jost, J.P.3
  • 34
    • 0029964505 scopus 로고    scopus 로고
    • A preference of histone H1 for methylated DNA
    • McArthur, M. and Thomas, J.O. (1996) A preference of histone H1 for methylated DNA. EMBO J. 15, 1705-1714
    • (1996) EMBO J. , vol.15 , pp. 1705-1714
    • McArthur, M.1    Thomas, J.O.2
  • 35
    • 0030071685 scopus 로고    scopus 로고
    • The methyl-CpG binding protein MeCP2 is essential for embryonic development in the mouse
    • Tate, P., Skarnes, W., and Bird, A. (1996) The methyl-CpG binding protein MeCP2 is essential for embryonic development in the mouse. Nature Genet. 12, 205-208
    • (1996) Nature Genet. , vol.12 , pp. 205-208
    • Tate, P.1    Skarnes, W.2    Bird, A.3
  • 36
    • 0030013906 scopus 로고    scopus 로고
    • Phosphorylation/ dephosphorylation of the repressor MDBP-2-H1 selectively affects the level of transcription from a methylated promoter in vitro
    • Bruhat, A. and Jost, J.P. (1996) Phosphorylation/ dephosphorylation of the repressor MDBP-2-H1 selectively affects the level of transcription from a methylated promoter in vitro. Nucleic Acids Res. 24, 1816-1821
    • (1996) Nucleic Acids Res. , vol.24 , pp. 1816-1821
    • Bruhat, A.1    Jost, J.P.2
  • 37
    • 0342437491 scopus 로고    scopus 로고
    • MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin
    • Nan, X., Campoy, F.J., and Bird, A. (1997) MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin. Cell 88, 471-481
    • (1997) Cell , vol.88 , pp. 471-481
    • Nan, X.1    Campoy, F.J.2    Bird, A.3
  • 38
    • 0029117138 scopus 로고
    • A DNA methylation site in the male-specific P450 (Cyp 2d-9) promoter and binding of the heteromeric transcription factor GABP
    • Yokomori, N., Kobayashi, R., Moore, R., Sueyoshi, T., and Negishi, M. (1995) A DNA methylation site in the male-specific P450 (Cyp 2d-9) promoter and binding of the heteromeric transcription factor GABP. Mol. Cell. Biol. 15, 5355-5362
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 5355-5362
    • Yokomori, N.1    Kobayashi, R.2    Moore, R.3    Sueyoshi, T.4    Negishi, M.5
  • 39
    • 0029865335 scopus 로고    scopus 로고
    • Novel AP-1 binding site created by DNA-methylation
    • Tulchinsky, E.M., Georgiev, G.P., and Lukanidin, E.M. (1996) Novel AP-1 binding site created by DNA-methylation. Oncogene 12, 1737-1745
    • (1996) Oncogene , vol.12 , pp. 1737-1745
    • Tulchinsky, E.M.1    Georgiev, G.P.2    Lukanidin, E.M.3
  • 40
    • 0027245556 scopus 로고
    • Methylation-enhanced binding of Sp1 to the stage selector element of the human γ-globin gene promoter may regulate developmental specificity of expression
    • Jane, S.M., Gumucio, D.L., Ney, P.A., Cunningham, J.M., and Nienhuis, A.W. (1993) Methylation-enhanced binding of Sp1 to the stage selector element of the human γ-globin gene promoter may regulate developmental specificity of expression. Mol. Cell. Biol. 13, 3272-3281
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 3272-3281
    • Jane, S.M.1    Gumucio, D.L.2    Ney, P.A.3    Cunningham, J.M.4    Nienhuis, A.W.5
  • 43
    • 0030479838 scopus 로고    scopus 로고
    • Isolation and expression of a Xenopus laevis DNA methyltransferase cDNA
    • Kimura, H., Ishihara, G., and Tajima, S. (1996) Isolation and expression of a Xenopus laevis DNA methyltransferase cDNA. J. Biochem. 120, 1182-1189
    • (1996) J. Biochem. , vol.120 , pp. 1182-1189
    • Kimura, H.1    Ishihara, G.2    Tajima, S.3
  • 45
    • 0023701018 scopus 로고
    • Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. The carboxyl-terminal domain of the mammalian enzymes is related to bacterial restriction methyltransferases
    • Bestor, T., Laudano, A., Mattaliano, R., and Ingram, V. (1988) Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. The carboxyl-terminal domain of the mammalian enzymes is related to bacterial restriction methyltransferases. J. Mol. Biol. 203, 971-983
    • (1988) J. Mol. Biol. , vol.203 , pp. 971-983
    • Bestor, T.1    Laudano, A.2    Mattaliano, R.3    Ingram, V.4
  • 46
    • 0029962499 scopus 로고    scopus 로고
    • New 5′ regions of the murine and human genes for DNA (cytosine-5)-methyltransferase
    • Yoder, J.A., Yen, R.-W.C., Vertino, P.M., Bestor, T.H., and Baylin, S.B. (1996) New 5′ regions of the murine and human genes for DNA (cytosine-5)-methyltransferase. J. Biol. Chem. 271, 31092-31097
    • (1996) J. Biol. Chem. , vol.271 , pp. 31092-31097
    • Yoder, J.A.1    Yen, R.-W.C.2    Vertino, P.M.3    Bestor, T.H.4    Baylin, S.B.5
  • 48
    • 0026439115 scopus 로고
    • A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei
    • Leonhardt, H., Page, A.W., Weier, H.-U., and Bestor, T.H. (1992) A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei. Cell 71, 865-873
    • (1992) Cell , vol.71 , pp. 865-873
    • Leonhardt, H.1    Page, A.W.2    Weier, H.-U.3    Bestor, T.H.4
  • 49
    • 0032519312 scopus 로고    scopus 로고
    • Multiple domains are involved in the targeting of the mouse DNA methyltransferase to the DNA replication foci
    • Liu, Y., Oakeley, E.J., Sun, L., and Jost, J.P. (1998) Multiple domains are involved in the targeting of the mouse DNA methyltransferase to the DNA replication foci. Nucleic Acids Res. 26, 1038-1045
    • (1998) Nucleic Acids Res. , vol.26 , pp. 1038-1045
    • Liu, Y.1    Oakeley, E.J.2    Sun, L.3    Jost, J.P.4
  • 51
    • 0025880514 scopus 로고
    • Growth regulation of mouse DNA methyltransferase gene expression
    • Szyf, M., Bozovic, V., and Tanigawa, G. (1991) Growth regulation of mouse DNA methyltransferase gene expression. J. Biol. Chem. 266, 10027-10030
    • (1991) J. Biol. Chem. , vol.266 , pp. 10027-10030
    • Szyf, M.1    Bozovic, V.2    Tanigawa, G.3
  • 52
    • 0029994420 scopus 로고    scopus 로고
    • In differentiating mouse myoblasts DNA methyltransferase is posttranscriptionally and posttranslationally regulated
    • Liu, Y., Sun, L., and Jost, J.P. (1996) In differentiating mouse myoblasts DNA methyltransferase is posttranscriptionally and posttranslationally regulated. Nucleic Acids Res. 24, 2718-2722
    • (1996) Nucleic Acids Res. , vol.24 , pp. 2718-2722
    • Liu, Y.1    Sun, L.2    Jost, J.P.3
  • 53
    • 0028787392 scopus 로고
    • Regulation of DNA methyltransferase during differentiation of F9 mouse embryonal carcinoma cells
    • Teubner, B. and Schulz, W.A. (1995) Regulation of DNA methyltransferase during differentiation of F9 mouse embryonal carcinoma cells. J. Cell Physiol. 165, 284-290
    • (1995) J. Cell Physiol. , vol.165 , pp. 284-290
    • Teubner, B.1    Schulz, W.A.2
  • 54
    • 0027096740 scopus 로고
    • Properties and localization of DNA methyltransferase in preimplantation mouse embryos: Implications for genomic imprinting
    • Carlson, L.L., Page, A.W., and Bestor, T.H. (1992) Properties and localization of DNA methyltransferase in preimplantation mouse embryos: implications for genomic imprinting. Genes Dev. 6, 2536-2541
    • (1992) Genes Dev. , vol.6 , pp. 2536-2541
    • Carlson, L.L.1    Page, A.W.2    Bestor, T.H.3
  • 55
    • 0025716275 scopus 로고
    • Changes in DNA methylation during mouse embryonic development in relation to X-chromosome activity and imprinting
    • Monk, M. (1990) Changes in DNA methylation during mouse embryonic development in relation to X-chromosome activity and imprinting. Phil. Trans. R. Soc. Lond. 326, 299-312
    • (1990) Phil. Trans. R. Soc. Lond. , vol.326 , pp. 299-312
    • Monk, M.1
  • 56
    • 0029129302 scopus 로고
    • Regulated synthesis and localization of DNA methyltransferase during spermatogenesis
    • Jue, K., Bestor, T.H., and Trasler, J.M. (1995) Regulated synthesis and localization of DNA methyltransferase during spermatogenesis. Biol. Reprod. 53, 561-569
    • (1995) Biol. Reprod. , vol.53 , pp. 561-569
    • Jue, K.1    Bestor, T.H.2    Trasler, J.M.3
  • 58
    • 0026008102 scopus 로고
    • Recognition of unusual DNA structures by human DNA (cytosine-5)methyltransferase
    • Smith, S.S., Kan, J.L.C., Baker, D.J., Kaplan, B.E., and Dembek, P. (1991) Recognition of unusual DNA structures by human DNA (cytosine-5)methyltransferase. J. Mol. Biol. 217, 39-51
    • (1991) J. Mol. Biol. , vol.217 , pp. 39-51
    • Smith, S.S.1    Kan, J.L.C.2    Baker, D.J.3    Kaplan, B.E.4    Dembek, P.5
  • 59
    • 0029127302 scopus 로고
    • 5-Methyl-2′-deoxycytidine in single-stranded DNA can act in cis to signal de novo DNA methylation
    • Christman, J.K., Sheikhnejad, G., Marasco, C., and Sufrin, J.R. (1995) 5-Methyl-2′-deoxycytidine in single-stranded DNA can act in cis to signal de novo DNA methylation. Proc. Natl. Acad. Sci. USA 92, 7347-7351
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 7347-7351
    • Christman, J.K.1    Sheikhnejad, G.2    Marasco, C.3    Sufrin, J.R.4
  • 60
    • 0025359356 scopus 로고
    • Post-meiotic gene expression
    • Erickson, R.P. (1990) Post-meiotic gene expression. Trends Genet. 6, 264-269
    • (1990) Trends Genet. , vol.6 , pp. 264-269
    • Erickson, R.P.1
  • 61
    • 0028014280 scopus 로고
    • Enhancement of receptor gene de novo methylation by fragments from the α-fetoprotein control region
    • Hasse, A. and Schulz, W.A. (1994) Enhancement of receptor gene de novo methylation by fragments from the α-fetoprotein control region. J. Biol. Chem. 269, 1821-1826
    • (1994) J. Biol. Chem. , vol.269 , pp. 1821-1826
    • Hasse, A.1    Schulz, W.A.2
  • 62
    • 0028939394 scopus 로고
    • Epigenetic gene inactivation induced by a cis-acting methylation center
    • Mummaneni, P., Walker, K.A., Bishop, P.L., and Turker, M.S. (1995) Epigenetic gene inactivation induced by a cis-acting methylation center. J. Biol. Chem. 270, 788-792
    • (1995) J. Biol. Chem. , vol.270 , pp. 788-792
    • Mummaneni, P.1    Walker, K.A.2    Bishop, P.L.3    Turker, M.S.4
  • 63
    • 0029803192 scopus 로고    scopus 로고
    • De novo DNA cytosine methyltransferase activities in mouse embryonic stem cells
    • Lei, H., Oh, S.P., Okano, M., Jüttermann, R., Goss, K.A., Jaenisch, R., and Li, E. (1996) De novo DNA cytosine methyltransferase activities in mouse embryonic stem cells. Development 122, 3195-3205
    • (1996) Development , vol.122 , pp. 3195-3205
    • Lei, H.1    Oh, S.P.2    Okano, M.3    Jüttermann, R.4    Goss, K.A.5    Jaenisch, R.6    Li, E.7
  • 64
    • 0024987810 scopus 로고
    • Establishment of de novo DNA methylation pattern. Transcription factor binding and deoxycytidine methylation at CpG and non-CpG sequences in an integrated adenovirus promoter
    • Toth, M., Müller, U., and Doerfler, W. (1990) Establishment of de novo DNA methylation pattern. Transcription factor binding and deoxycytidine methylation at CpG and non-CpG sequences in an integrated adenovirus promoter. J. Mol. Biol. 214, 673-683
    • (1990) J. Mol. Biol. , vol.214 , pp. 673-683
    • Toth, M.1    Müller, U.2    Doerfler, W.3
  • 66
    • 0029035771 scopus 로고
    • Overexpression of DNA methyltransferase in myoblast cells accelerates myotube formation
    • Takagi, H., Tajima, S., and Asano, A. (1995) Overexpression of DNA methyltransferase in myoblast cells accelerates myotube formation. Eur. J. Biochem. 231, 282-291
    • (1995) Eur. J. Biochem. , vol.231 , pp. 282-291
    • Takagi, H.1    Tajima, S.2    Asano, A.3
  • 67
    • 0025637814 scopus 로고
    • Dynamics of demethylation and activation of the α-actin gene in myoblasts
    • Paroush, Z., Keshet, I., Yisraeli, J., and Cedar, H. (1990) Dynamics of demethylation and activation of the α-actin gene in myoblasts. Cell 63, 1229-1237
    • (1990) Cell , vol.63 , pp. 1229-1237
    • Paroush, Z.1    Keshet, I.2    Yisraeli, J.3    Cedar, H.4
  • 68
    • 0028328632 scopus 로고
    • B cell-specific demethylation: A novel role for the intronic א chain enhancer sequence
    • Lichtenstein, M., Keini, G., Cedar, H., and Bergman, Y. (1994) B cell-specific demethylation: a novel role for the intronic א chain enhancer sequence. Cell 76, 913-923
    • (1994) Cell , vol.76 , pp. 913-923
    • Lichtenstein, M.1    Keini, G.2    Cedar, H.3    Bergman, Y.4
  • 69
    • 0030744874 scopus 로고    scopus 로고
    • Cis-elements required for the demethylation of the mouse M-lysozyme downstream enhancer
    • Schmitz, A., Short, M., Ammerpohl, O., Asbrand, C., Nickel, J., and Renkawitz, R. (1997) Cis-elements required for the demethylation of the mouse M-lysozyme downstream enhancer. J. Biol. Chem. 272, 20850-20856
    • (1997) J. Biol. Chem. , vol.272 , pp. 20850-20856
    • Schmitz, A.1    Short, M.2    Ammerpohl, O.3    Asbrand, C.4    Nickel, J.5    Renkawitz, R.6
  • 71
    • 0027960055 scopus 로고
    • Sp1 sites in the mouse aprt gene promoter are required to prevent methylation of the CpG island
    • Macleod, D., Charlton, J., Mullins, J., and Bird, A.P. (1994) Sp1 sites in the mouse aprt gene promoter are required to prevent methylation of the CpG island. Gen. Dev. 8, 2282-2292
    • (1994) Gen. Dev. , vol.8 , pp. 2282-2292
    • Macleod, D.1    Charlton, J.2    Mullins, J.3    Bird, A.P.4
  • 72
    • 0002923260 scopus 로고    scopus 로고
    • Mechanism of DNA demethylation in vertebrates and its biological significance
    • Russo, V.E.A., Martienssen, R.A., and Riggs, A.D., eds., Cold Spring Harbor Laboratory Press, New York
    • Jost, J.P. (1996) Mechanism of DNA demethylation in vertebrates and its biological significance in Epigenetic Mechanisms of Gene Regulation (Russo, V.E.A., Martienssen, R.A., and Riggs, A.D., eds.) pp. 109-125, Cold Spring Harbor Laboratory Press, New York
    • (1996) Epigenetic Mechanisms of Gene Regulation , pp. 109-125
    • Jost, J.P.1
  • 73
    • 1842289276 scopus 로고    scopus 로고
    • The RNA moiety of chick embryo 5-methylcytosine-DNA glycosylase targets DNA demethylation
    • Jost, J.P., Frémont, M., Siegmann, M., and Hofsteenge, J. (1997) The RNA moiety of chick embryo 5-methylcytosine-DNA glycosylase targets DNA demethylation. Nucleic Acids Res. 25, 4545-4550
    • (1997) Nucleic Acids Res. , vol.25 , pp. 4545-4550
    • Jost, J.P.1    Frémont, M.2    Siegmann, M.3    Hofsteenge, J.4
  • 74
    • 0030572637 scopus 로고    scopus 로고
    • DNA demethylation in vitro: Involvement of RNA
    • Weiss, A., Keshet, I., Razin, A., and Cedar, H. (1996) DNA demethylation in vitro: involvement of RNA. Cell 86, 709-718
    • (1996) Cell , vol.86 , pp. 709-718
    • Weiss, A.1    Keshet, I.2    Razin, A.3    Cedar, H.4


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