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Volumn 73, Issue 4, 1997, Pages 1874-1884

Pore residues critical for μ-CTX binding to rat skeletal muscle Na+ channels revealed by cysteine mutagenesis

Author keywords

[No Author keywords available]

Indexed keywords

CONOTOXIN; CYSTEINE; MESYLIC ACID; SODIUM CHANNEL; SODIUM ION; SULFONIC ACID DERIVATIVE; THIOL GROUP; TRYPTOPHAN;

EID: 0030770381     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(97)78218-3     Document Type: Article
Times cited : (38)

References (49)
  • 1
    • 0027987062 scopus 로고
    • Identification of acetylcholine receptor channel-lining residues in the entire M2 segment of the alpha-subunit
    • Akabas, M. H., C. Kauffmann, P. Archdeacon, and A. Karlin. 1994a. Identification of acetylcholine receptor channel-lining residues in the entire M2 segment of the alpha-subunit. Neuron. 13:919-927.
    • (1994) Neuron , vol.13 , pp. 919-927
    • Akabas, M.H.1    Kauffmann, C.2    Archdeacon, P.3    Karlin, A.4
  • 2
    • 0028264188 scopus 로고
    • Amino acid residues lining the chloride channel of the cystic fibrosis transmembrane regulator
    • Akabas, M. H., C. Kauffmann, T. A. Cook, and P. Archdecon. 1994b. Amino acid residues lining the chloride channel of the cystic fibrosis transmembrane regulator. J. Biol. Chem. 269:14865-14868.
    • (1994) J. Biol. Chem. , vol.269 , pp. 14865-14868
    • Akabas, M.H.1    Kauffmann, C.2    Cook, T.A.3    Archdecon, P.4
  • 3
    • 0026485739 scopus 로고
    • Acetylcholine receptor channel structure probed in cysteine-substitution mutants
    • Akabas, M. H., D. A. Stauffer, M. Xu, and A. Karlin. 1992. Acetylcholine receptor channel structure probed in cysteine-substitution mutants. Science. 258:307-310.
    • (1992) Science , vol.258 , pp. 307-310
    • Akabas, M.H.1    Stauffer, D.A.2    Xu, M.3    Karlin, A.4
  • 4
    • 0026755899 scopus 로고
    • Molecular localization of an ion-binding site within the pore of mammalian sodium channels
    • Backx, P., D. Yue, J. Lawrence, E. Marban, and G. Tomaselli. 1992. Molecular localization of an ion-binding site within the pore of mammalian sodium channels. Science. 257:248-251.
    • (1992) Science , vol.257 , pp. 248-251
    • Backx, P.1    Yue, D.2    Lawrence, J.3    Marban, E.4    Tomaselli, G.5
  • 5
    • 0026657359 scopus 로고
    • Action of derivatives of μ-conotoxin GIIIA on sodium channels. Single amino acid substitutions in the toxin separately affect association and dissociation rates
    • Becker, S., E. Prusak-Sochazewski, G. Zamponi, A. G. Beck-Sickinger, R. D. Gordon, and R. J. French. 1992. Action of derivatives of μ-conotoxin GIIIA on sodium channels. Single amino acid substitutions in the toxin separately affect association and dissociation rates. Biochemistry. 31:8229-8238.
    • (1992) Biochemistry , vol.31 , pp. 8229-8238
    • Becker, S.1    Prusak-Sochazewski, E.2    Zamponi, G.3    Beck-Sickinger, A.G.4    Gordon, R.D.5    French, R.J.6
  • 6
    • 0027462342 scopus 로고
    • + current conducted by the rat skeletal muscle α subunit by coexpression with a human brain β subunit
    • + current conducted by the rat skeletal muscle α subunit by coexpression with a human brain β subunit. Pflugers Arch. 423: 155-157.
    • (1993) Pflugers Arch. , vol.423 , pp. 155-157
    • Cannon, S.C.1    McClatchey, A.I.2    Gusella, J.F.3
  • 7
    • 0008059596 scopus 로고
    • Characterizing the μ-conotoxin binding site on Na channel with toxin analogues and channel mutations
    • Chahine, M., L.-Q. Chen, N. Fotouhi, R. Walsky, D. Fry, R. Horn, and R. G. Kallen. 1995. Characterizing the μ-conotoxin binding site on Na channel with toxin analogues and channel mutations. Receptors Channels. 3:164-174.
    • (1995) Receptors Channels , vol.3 , pp. 164-174
    • Chahine, M.1    Chen, L.-Q.2    Fotouhi, N.3    Walsky, R.4    Fry, D.5    Horn, R.6    Kallen, R.G.7
  • 8
    • 0026760836 scopus 로고
    • Chimeric study of sodium channels from rat skeletal and cardiac muscle
    • Chen, L.-Q., M. Chahine, R. G. Kallen, R. L. Barchi, and R. Horn. 1992. Chimeric study of sodium channels from rat skeletal and cardiac muscle. FEBS Lett. 309:253-257
    • (1992) FEBS Lett. , vol.309 , pp. 253-257
    • Chen, L.-Q.1    Chahine, M.2    Kallen, R.G.3    Barchi, R.L.4    Horn, R.5
  • 9
    • 15844394267 scopus 로고    scopus 로고
    • Depth assymetries of the pore-lining segments of the sodium channel revealed by cysteine mutagenesis
    • Chiamvimonvat, N., M. Perez-Garcia, R. Ranjan, E. Marban, and G. F. Tomaselli. 1996. Depth assymetries of the pore-lining segments of the sodium channel revealed by cysteine mutagenesis. Neuron. 16: 1037-1047.
    • (1996) Neuron , vol.16 , pp. 1037-1047
    • Chiamvimonvat, N.1    Perez-Garcia, M.2    Ranjan, R.3    Marban, E.4    Tomaselli, G.F.5
  • 11
    • 0027471751 scopus 로고
    • 3H]saxitoxin binding to tetradotoxin-resistant and -sensitive sodium channels. A two-site structural model of ion/toxin interaction
    • 3H]saxitoxin binding to tetradotoxin-resistant and -sensitive sodium channels. A two-site structural model of ion/toxin interaction. J. Gen. Physiol. 101:153-182.
    • (1993) J. Gen. Physiol. , vol.101 , pp. 153-182
    • Doyle, D.D.1    Guo, Y.2    Lustig, S.L.3    Satin, L.4    Rogart, R.B.5    Fozzard, H.A.6
  • 13
    • 0030058733 scopus 로고    scopus 로고
    • Interactions between a pore-blocking peptide and the voltage-sensor of the sodium channel: An electrostatic approach to channel geometry
    • French, R. J., E. Prusak-Sochaczewski, G. W. Zamponi, S. Becker, A. S. Kularanta, and R. Horn. 1996. Interactions between a pore-blocking peptide and the voltage-sensor of the sodium channel: an electrostatic approach to channel geometry. Neuron. 16:407-413.
    • (1996) Neuron , vol.16 , pp. 407-413
    • French, R.J.1    Prusak-Sochaczewski, E.2    Zamponi, G.W.3    Becker, S.4    Kularanta, A.S.5    Horn, R.6
  • 14
    • 0028276482 scopus 로고
    • + channel: Peptide and channel residues mediating molecular recognition
    • + channel: peptide and channel residues mediating molecular recognition. Neuron. 12:1377-1388.
    • (1994) Neuron , vol.12 , pp. 1377-1388
    • Goldstein, S.A.N.1    Pheasant, D.J.2    Miller, C.3
  • 15
  • 16
    • 0030051784 scopus 로고    scopus 로고
    • Agitoxin footprinting the Shaker potassium channel pore
    • Gross, A., and R. MacKinnon. 1996. Agitoxin footprinting the Shaker potassium channel pore. Neuron. 16:399-406.
    • (1996) Neuron , vol.16 , pp. 399-406
    • Gross, A.1    MacKinnon, R.2
  • 17
    • 0026698250 scopus 로고
    • Molecular basis for pharmacological differences between brain and cardiac sodium channels
    • Heinemann, S. H., H. Terlau, and K. Imoto. 1992a. Molecular basis for pharmacological differences between brain and cardiac sodium channels. Pflugers Arch. 422:90-92.
    • (1992) Pflugers Arch. , vol.422 , pp. 90-92
    • Heinemann, S.H.1    Terlau, H.2    Imoto, K.3
  • 18
    • 0026517122 scopus 로고
    • Calcium channel characteristics conferred on the sodium channel by single mutations
    • Heinemann, S. H., H. Terlau, W. Stuhmer, K. Imoto, and S. Numa. 1992b. Calcium channel characteristics conferred on the sodium channel by single mutations. Nature. 356:441-444.
    • (1992) Nature , vol.356 , pp. 441-444
    • Heinemann, S.H.1    Terlau, H.2    Stuhmer, W.3    Imoto, K.4    Numa, S.5
  • 19
    • 0028987938 scopus 로고
    • + channel pore through mutant cycles with a peptide inhibitor
    • + channel pore through mutant cycles with a peptide inhibitor. Science. 268:307-310.
    • (1992) Science , vol.268 , pp. 307-310
    • Hidalgo, P.1    MacKinnon, R.2
  • 20
    • 0030016085 scopus 로고    scopus 로고
    • Three-dimensional solution structure of μ-conotoxin GIIIB, a specific blocker of skeletal muscle sodium channels
    • Hill, J. M., P. F. Alewood, and D. J. Craik. 1996. Three-dimensional solution structure of μ-conotoxin GIIIB, a specific blocker of skeletal muscle sodium channels. Biochemistry. 35:8824-8835.
    • (1996) Biochemistry , vol.35 , pp. 8824-8835
    • Hill, J.M.1    Alewood, P.F.2    Craik, D.J.3
  • 24
    • 0022930560 scopus 로고
    • Structure-activity relations of tetrodotoxin, saxitoxin and analogues
    • Kao, C. Y. 1986. Structure-activity relations of tetrodotoxin, saxitoxin and analogues. Ann. N.Y. Acad. Sci. USA. 479:52-67.
    • (1986) Ann. N.Y. Acad. Sci. USA , vol.479 , pp. 52-67
    • Kao, C.Y.1
  • 25
    • 0023729685 scopus 로고
    • Evidence for the involvement of more than one mRNA species in controlling the inactivation process of rat and rabbit brain Na channels expressed in Xenopus oocytes
    • Krafte, D. S., T. P. Snutch, J. P. Leonard, N. Davidson, and H. A. Lester. 1988. Evidence for the involvement of more than one mRNA species in controlling the inactivation process of rat and rabbit brain Na channels expressed in Xenopus oocytes. Neuroscience. 8:2859-2868.
    • (1988) Neuroscience , vol.8 , pp. 2859-2868
    • Krafte, D.S.1    Snutch, T.P.2    Leonard, J.P.3    Davidson, N.4    Lester, H.A.5
  • 26
    • 2642699794 scopus 로고
    • Rapid and efficient site-specific mutagenesis without phenotypic selection
    • Kunkel, T. A. 1985. Rapid and efficient site-specific mutagenesis without phenotypic selection. Proc. Natl. Acad. Sci. USA. 82:488-492.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 488-492
    • Kunkel, T.A.1
  • 27
    • 0028941130 scopus 로고
    • + channel probed by sulfhydryl-specific reagents after cysteine-scanning mutagenesis
    • + channel probed by sulfhydryl-specific reagents after cysteine-scanning mutagenesis. Biophys. J. 68:900-905.
    • (1995) Biophys. J. , vol.68 , pp. 900-905
    • Kürz, L.L.1    Zühlke, R.D.2    Zhang, H.-J.3    Joho, R.H.4
  • 29
    • 0343470275 scopus 로고    scopus 로고
    • + channel pore structure using single and multiple cysteine substitutions
    • Abstr.
    • + channel pore structure using single and multiple cysteine substitutions. Biophys. J. 70:A24 (Abstr.).
    • (1996) Biophys. J. , vol.70
    • Li, R.1    Tsushima, R.2    Backx, P.3
  • 31
    • 0020562748 scopus 로고
    • Isolation and amino acid compositions of geographutoxin I and II from the marine snail Conus geographus Linne
    • Nakamura, H., J. Kobayashi, Y. Ohizumi, and Y. Hirata. 1983. Isolation and amino acid compositions of geographutoxin I and II from the marine snail Conus geographus Linne. Experientia. 39:590-591.
    • (1983) Experientia , vol.39 , pp. 590-591
    • Nakamura, H.1    Kobayashi, J.2    Ohizumi, Y.3    Hirata, Y.4
  • 32
    • 0024811092 scopus 로고
    • A single point mutation confers tetrodotoxin and saxitoxin insensitivity on the sodium channel-II
    • Noda, M., H. Suzuki, S. Numa, and W. Stuhmer. 1989. A single point mutation confers tetrodotoxin and saxitoxin insensitivity on the sodium channel-II. FEBS Lett. 259:213.
    • (1989) FEBS Lett. , vol.259 , pp. 213
    • Noda, M.1    Suzuki, H.2    Numa, S.3    Stuhmer, W.4
  • 35
    • 0026666693 scopus 로고
    • Mapping function to structure in a channel-blocking peptide: Electrostatic mutants of charybdotoxin
    • Park, C. S., and C. Miller. 1992. Mapping function to structure in a channel-blocking peptide: electrostatic mutants of charybdotoxin. Biochemistry: 31:7749-7755.
    • (1992) Biochemistry , vol.31 , pp. 7749-7755
    • Park, C.S.1    Miller, C.2
  • 36
    • 0029070117 scopus 로고
    • + pore structure revealed by reporter cysteines at inner and outer surfaces
    • + pore structure revealed by reporter cysteines at inner and outer surfaces. Neuron. 14:1055-1063.
    • (1995) Neuron , vol.14 , pp. 1055-1063
    • Pascual, J.M.1    Shieh, C.-C.2    Kirsch, G.E.3    Brown, A.M.4
  • 39
    • 0026637366 scopus 로고
    • A mutant of TTX-resistant cardiac sodium channels with TTX-sensitive properties
    • Satin, J., J. W. Kyle, M. Chen, P. Bell, L. L. Cribbs, H. A. Fozzard, and R. B. Rogart. 1992. A mutant of TTX-resistant cardiac sodium channels with TTX-sensitive properties. Science. 256:1202-1205.
    • (1992) Science , vol.256 , pp. 1202-1205
    • Satin, J.1    Kyle, J.W.2    Chen, M.3    Bell, P.4    Cribbs, L.L.5    Fozzard, H.A.6    Rogart, R.B.7
  • 42
    • 0028117321 scopus 로고
    • + channel structure from a complete functional map of the molecular surface of charybdotoxin
    • + channel structure from a complete functional map of the molecular surface of charybdotoxin. Biochemistry. 33:443-450.
    • (1994) Biochemistry , vol.33 , pp. 443-450
    • Stampe, P.1    Kolmakova-Partensky, L.2    Miller, C.3
  • 43
    • 0028180093 scopus 로고
    • The μ1 skeletal muscle sodium channel: Mutation E403Q eliminated sensitivity to tetrodotoxin but not to μ-conotoxin GIIIA and GIIIB
    • Stephan M. M., J. F. Potts, and W. S. Agnew. 1994. The μ1 skeletal muscle sodium channel: mutation E403Q eliminated sensitivity to tetrodotoxin but not to μ-conotoxin GIIIA and GIIIB. J. Membr. Biol. 137:1-8.
    • (1994) J. Membr. Biol. , vol.137 , pp. 1-8
    • Stephan, M.M.1    Potts, J.F.2    Agnew, W.S.3
  • 46
    • 0030894992 scopus 로고    scopus 로고
    • Altered ionic selectivity of the sodium channel revealed by cysteine mutations within the pore
    • Tsushima, R. G., R. A. Li, and P. H. Backx. 1997a. Altered ionic selectivity of the sodium channel revealed by cysteine mutations within the pore. J. Gen. Physiol. 109:463-475.
    • (1997) J. Gen. Physiol. , vol.109 , pp. 463-475
    • Tsushima, R.G.1    Li, R.A.2    Backx, P.H.3
  • 47
  • 48
    • 0027078665 scopus 로고
    • Structure-activity relationships of μ-conotoxin GIIIA: Structure determination of active and inactive sodium channel blocker peptide by NMR and simulated annealing calculations
    • Wakamatsu, K., D. Kohda, H. Hatanaka, J. M. Lancelin, Y. Ishida, M. Oya, H. Nakamura, F. Inagaki, and K. Sato. 1992. Structure-activity relationships of μ-conotoxin GIIIA: structure determination of active and inactive sodium channel blocker peptide by NMR and simulated annealing calculations. Biochemistry. 31:12577-12584.
    • (1992) Biochemistry , vol.31 , pp. 12577-12584
    • Wakamatsu, K.1    Kohda, D.2    Hatanaka, H.3    Lancelin, J.M.4    Ishida, Y.5    Oya, M.6    Nakamura, H.7    Inagaki, F.8    Sato, K.9
  • 49
    • 0026045546 scopus 로고
    • Multiple gating modes and the effect of modulating factors on the μ1 sodium channel
    • Zhou, J., J. F. Potts, J. S. Trimmer, W. S. Agnew, and F. J. Sigworth. 1991. Multiple gating modes and the effect of modulating factors on the μ1 sodium channel. Neuron. 7:775-785.
    • (1991) Neuron , vol.7 , pp. 775-785
    • Zhou, J.1    Potts, J.F.2    Trimmer, J.S.3    Agnew, W.S.4    Sigworth, F.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.