Distinct substrate preference of human and mouse N-methylpurine-DNA glycosylases

Carcinogenesis

Volumn 17, Issue 10, 1996, Pages 2177-2182

  Roy, Rabindra ^a   Kennel, S J ^a,b   Mitra, Sankar ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

^b OAK RIDGE NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 METHYLADENINE; 7 METHYLGUANINE; DNA GLYCOSYLTRANSFERASE; GUANINE DERIVATIVE; HYBRID PROTEIN; PURINE DERIVATIVE; RECOMBINANT PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SPECIFICITY; ESCHERICHIA COLI; HUMAN; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANIMALS; DNA GLYCOSYLASES; DNA REPAIR; HUMANS; MICE; N-GLYCOSYL HYDROLASES; RECOMBINANT PROTEINS; SPECIES SPECIFICITY; SUBSTRATE SPECIFICITY;

EID: 0029829188     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/17.10.2177     Document Type: Article

References (39)

1. Beranek, D.T. (1990) Distribution of methyl and ethyl adducts following alkylation with monofunctional alkylating agents. Mutat. Res., 231, 11-30.
2. Boiteux, S., Huisman, O. and Laval, J. (1984) 3-Methyladenine residues in DNA induce the SOS function SfiA in Escherichia coli. EMBO J., 25, 2569-2573
3. Larson, K., Sahm, J., Shenkar, R. and Strauss, B. (1985) Methylation-induced blocks to in vitro DNA replication. Mutat. Res., 150, 77-84.
4. Randall, S.K., Eritja, R., Kaplan, B.E., Petruska, J. and Goodman, M.F. (1987) Nucleotide insertion kinetics opposite abasic lesions in DNA. J. Biol. Chem., 262, 6864-6870.
5. Loeb, L.A. and Preston, B.D. (1986) Mutagenesis by apurinic/apyrimidinic sites. Annu. Rev. Genet., 20, 201-230.
6. Lindahl, T., Sedgwick, B., Seckiguchi, M. and Nakabeppu, Y. (1988) Regulation and expression of the adaptive response to alkylating agents. Annu. Rev. Biochem., 57, 133-157.
7. Volkert, M.R. (1988) Adaptive response of Escherichia coli to alkylation damage. Environ. Mol. Mutagen., 11, 241-255.
8. Bjelland, S. and Seeberg, E. (1987) Purification and characterization of 3-methyladenine DNA glycosylase 1 from Escherichia coli. Nucleic Acids Res., 15, 2787-2801.
9. Saparbaev, M. and Laval, J. (1994) Excision of hypoxanthine from DNA containing dIMP residues by the Escherichia coli, yeast, rat and human alkylpurine DNA glycosylases. Proc. Natl Acad. Sci. USA, 91, 5873-5877.
10. 6-ethenoadenine when present in DNA. Nucleic Acids Res., 23, 3750-3755.
11. 2,3-ethenoguanine from chloroacetaldehyde-treated DNA by Escherichia coli 3-methyladenine-DNA glycosylase. Proc. Natl Acad Sci. USA, 89, 9331-9334.
12. Bjelland, S., Birkeland, N.K., Benneche, T., Volden, G. and Seeberg, E. (1994) DNA glycosylase activities for thymine residues oxidized in the methyl group are functions of the AlkA enzyme in Escherichia coli. J. Biol. Chem., 269, 30489-30495.
13. Chakravarti, D., Ibeanu, G.C., Tano, K. and Mitra, S. (1991) Cloning and expression in Escherichia coli of human cDNA encoding the DNA repair protein N-methylpurine-DNA glycosylase. J. Biol. Chem., 266, 15710-15715.
14. Engelward, B.P., Boosalis, M.J., Chen, B.J., Deng, Z., Siciliano, M.J. and Samson, L.D. (1993) Cloning and characterization of a mouse 3-methyladenine/7-methylguanine/3-methylguanme DNA-glycosylase cDNA whose gene maps to chromosome 11. Carcinogenesis, 14, 175-181.
15. Bessho, T., Roy, R., Yamamoto, K., Kasai, H., Nishimura, S., Tano, K. and Mitra, S. (1993) Repair of 8-hydroxyguanine in DNA by mammalian N-methylpurine-DNA glycosylase. Proc. Natl Acad. Sci. USA, 90, 8901-8904.
16. Dosanjh, M.K., Chenna, A., Kim, E., Frankel-Conrat, H., Samson, L. and Singer, B. (1994) All four known cyclic adducts formed in DNA by the vinyl chloride metabolite chloroacetaldehyde are released by a human DNA glycosylase. Proc. Natl Acad. Sci. USA, 91, 1024-1028.
17. 6-ethenoadenine is preferred over 3-methyladenine as substrate by a cloned human N-methylpurine-DNA glycosylase (3-methyladenine-DNA glycosylase, MPG). Biochemistry, 33, 1624-1628.
18. Gallagher, P.E. and Brent, T.P. (1984) Further purification and characterization of human 3-methyladenine-DNA glycosylase. Evidence for broad specificity. Biochim. Biophys. Acta, 782, 394-401.
19. 6-alkylguanines or 1-alkyladenines. Proc. Natl Acad. Sci. USA, 78, 856-860.
20. Samson, L., Derfler, B., Boosalis, M. and Call, K. (1991) Cloning and characterization of a 3-methyladenine DNA glycosylase cDNA from human cells whose gene maps to chromosome 16. Proc. Natl Acad. Sci. USA, 88, 9127-9131.
21. O'Connor, T.R. and Laval, F. (1990) Isolation and structure of a cDNA expressing a mammalian 3-methyladenine-DNA glycosylase. EMBO J., 9, 3337-3342.
22. Tatsuka, M., Ibeanu, G.C., Izumi, T., Narayan, S., Ramana, C.V., Kim, N.K., Kang, W., Roy, G. and Mitra, S. (1995) Structural organization of the mouse DNA repair gene, N-methylpurine-DNA glycosylase. DNA Cell Biol., 14, 37-45.
23. Vickers, M.A., Vyas, P., Harris, P.C., Simmons, D.L. and Higgs, D.R. (1993) Structure of the human 3-methyladenine DNA glycosylase gene and localization close to the 16p telomere. Proc. Natl Acad. Sci. USA, 90, 3437-3441.
24. O'Connor, T.R. (1993) Purification and characterization of human 3-methyladenine-DNA glycosylase. Nucleic Acids Res., 21, 5561-5569.
25. Mitra, S., Roy, R., Tano, K., Ibeanu, G.C., Dunn, W.C., Kim, N.K., Natarajan, A.T., Hartenstein, B. and Kaina, B. (1993) Alkylation damage repair in mammalian genomes. In Bohr, V., Wassermann, K. and Kraemer, K.H. (eds), Alfred Benzon Symposium 35: DNA Repair Mechanism. Copenhagen, pp. 328-342.
26. Volkert, M.R., Nguyen, D.C. and Beard, K.C. (1986) Escherichia coli gene induction by alkylation treatment. Genetics, 112, 11-26.
27. Vieira, J. and Messing, J. (1982) The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers. Gene, 19, 259-268.
28. Chetsanga, C.J. and Lindahl, T. (1979) Release of 7-methylguanine residues whose imidazole rings have been opened from damaged DNA by a DNA glycosylase from Escherichia coli. Nucleic Acids Res., 6, 3673-3684.
29. Roy, R., Brooks, C. and Mitra, S. (1994) Purification and biochemical characterization of recombinanl N-methylpurine-DNA glycosylase of the mouse. Biochemistry, 33, 15131-15140.
30. Tatsuka, M., Mitsui, H., Wada, M., Nagata, A., Nojima, H. and Okayama,H. (1992) Elongation factor-1 alpha gene determines susceptibility to transformation. Nature, 359, 333-336.
31. Sanger, F., Nicklen, S. and Coulson, A.R. (1977) DNA sequencing with chain-terminating inhibitors. Proc. Natl Acad. Sci. USA, 74, 5463-5467.
32. Dente, L., Cesareni, G. and Cortese, R. (1983) pEMBL: a new family of single stranded plasmid. Nucleic Acids Res., 11, 1645-1655.
33. Sayers, J.R., Schmidt, W. and Eckstein, F. (1988) 5′ → 3′ Exonudeases in phosphorothioate-based oligonucleotide-directed mutagenesis. Nucleic Adds Res., 16, 791-802.
34. 6-methylguanine in DNA in inbred mice. Mech. Ageing Dev., 48, 43-52.
35. Abe, M., Goto, T., Kennel, S.J., Wolfenbarger, D., Macy, S.D., Weiss, D.T. and Solomon, A. (1993) Production and immunodiagnostic applications of antihuman light chain monoclonal antibodies. Am. J. Clin. Pathol., 100, 67-74.
36. Smith, P.K. et al. (1985) Measurement of protein using bicinchoninic acid. Anal. Biochem., 150, 76-85.
37. Tchou, J., Kasai, H., Shibutani, S., Chung, M.-H., Laval, J., Grollman, A.P. and Nishimura, S. (1991) 8-Oxoguanine (8-hydroxyguanine) DNA glycosylase and its substrate specificity. Proc. Natl Acad. Sci. USA, 88, 4690-4694.
38. de Oliveira, R., van der Kemp, P.A., Geiger, T.D., Nehls, P. and Boiteux, S. (1994) Formamidopyrimidine DNA glycosylase in the yeast Saccharomyces cerevisiae. Nucleic Acids Res., 22, 3760-3764.
39. Teo, I., Sedgwick, B., Demple, B., Li, B. and Lindahl, T. (1984) Induction of resistance to alkylating agents in E.coli: the ada+ gene product serves both as a regulatory protein and as an enzyme for repair of mutagenic damage. EMBO J., 3, 2151-2157.