메뉴 건너뛰기




Volumn 348, Issue 9026, 1996, Pages 519-524

Zileuton

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; BRONCHODILATING AGENT; HISTAMINE; LEUKOTRIENE; LEUKOTRIENE B4; LEUKOTRIENE E4; LIPOXYGENASE; PROSTAGLANDIN; THROMBOXANE; ZILEUTON;

EID: 0030600338     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(95)12297-4     Document Type: Article
Times cited : (103)

References (38)
  • 1
    • 0025288071 scopus 로고
    • Has the prevalence of asthma increased in children? Evidence from the national study of health and growth 1973-1986
    • 1 Burney PGJ, Chinn S, Rona RJ. Has the prevalence of asthma increased in children? Evidence from the national study of health and growth 1973-1986. BMJ 1990; 300: 1306-10.
    • (1990) BMJ , vol.300 , pp. 1306-1310
    • Burney, P.G.J.1    Chinn, S.2    Rona, R.J.3
  • 2
    • 0023775707 scopus 로고
    • International trends in asthma mortality: 1970 to 1985
    • 2 Jackson RJ, Sears MR, Beaglehole R, et al. International trends in asthma mortality: 1970 to 1985. Chest 1988; 94: 914-18.
    • (1988) Chest , vol.94 , pp. 914-918
    • Jackson, R.J.1    Sears, M.R.2    Beaglehole, R.3
  • 3
    • 0026566147 scopus 로고
    • The economic evaluation of asthma in the United States
    • 3 Weiss KB, Gergen PJ, Hodgson TA. The economic evaluation of asthma in the United States. N Engl J Med 1992; 326: 862-66.
    • (1992) N Engl J Med , vol.326 , pp. 862-866
    • Weiss, K.B.1    Gergen, P.J.2    Hodgson, T.A.3
  • 4
    • 0025223381 scopus 로고
    • Regular inhaled beta-agonist treatment in bronchial asthma
    • 4 Sears MR, Taylor DR, Print CG, et al. Regular inhaled beta-agonist treatment in bronchial asthma. Lancet 1990; 336: 1391-96.
    • (1990) Lancet , vol.336 , pp. 1391-1396
    • Sears, M.R.1    Taylor, D.R.2    Print, C.G.3
  • 6
    • 0025810991 scopus 로고
    • The potential roles of leukotrienes in bronchial asthma
    • 6 Piacentini GL, Kaliner MA. The potential roles of leukotrienes in bronchial asthma. Am Rev Respir Dis 1991; 143: S96-99.
    • (1991) Am Rev Respir Dis , vol.143
    • Piacentini, G.L.1    Kaliner, M.A.2
  • 7
    • 0019971503 scopus 로고
    • Slow reacting substances, leukotrienes C4 and D4, increase the release of mucus from human airways in vitro
    • 7 Marom Z, Shellhamer JH, Back MK, et al. Slow reacting substances, leukotrienes C4 and D4, increase the release of mucus from human airways in vitro. Am Rev Respir Dis 1982; 126: 449-51.
    • (1982) Am Rev Respir Dis , vol.126 , pp. 449-451
    • Marom, Z.1    Shellhamer, J.H.2    Back, M.K.3
  • 8
    • 0028566488 scopus 로고
    • The role of leukotrienes in inflammation
    • 8 Henderson WR. The role of leukotrienes in inflammation. Ann Intern Med 1994; 121: 684-97.
    • (1994) Ann Intern Med , vol.121 , pp. 684-697
    • Henderson, W.R.1
  • 9
    • 0019254822 scopus 로고
    • Leukotrienes are potent constrictors of human bronchi
    • 9 Dahlen SE, Hedqvist P, Hammarstrom S, et al. Leukotrienes are potent constrictors of human bronchi. Nature 1980; 228: 484-86.
    • (1980) Nature , vol.228 , pp. 484-486
    • Dahlen, S.E.1    Hedqvist, P.2    Hammarstrom, S.3
  • 10
    • 0025164256 scopus 로고
    • Leukotrienes and other products of the 5-lipoxygenase pathway
    • 10 Lewis RA, Austen KF, Soberman RJ. Leukotrienes and other products of the 5-lipoxygenase pathway. N Engl J Med 1990; 323: 645-55.
    • (1990) N Engl J Med , vol.323 , pp. 645-655
    • Lewis, R.A.1    Austen, K.F.2    Soberman, R.J.3
  • 11
    • 0025284206 scopus 로고
    • 4 in bronchoalveolar lavage fluid from atopic asthmatics after endobronchial allergen challenge
    • 4 in bronchoalveolar lavage fluid from atopic asthmatics after endobronchial allergen challenge. Am Rev Respir Dis 1990; 142: 112-19.
    • (1990) Am Rev Respir Dis , vol.142 , pp. 112-119
    • Wenzel, S.E.1    Larsen, G.L.2    Johnston, K.3
  • 13
    • 0026526828 scopus 로고
    • Increased excretion of leukotriene E4 during aspirin-induced asthma
    • 13 Knapp HR, Sladek K, FitzGerald GA. Increased excretion of leukotriene E4 during aspirin-induced asthma. J Lab Clin Invest 1992; 119: 48-51.
    • (1992) J Lab Clin Invest , vol.119 , pp. 48-51
    • Knapp, H.R.1    Sladek, K.2    FitzGerald, G.A.3
  • 14
    • 0000966697 scopus 로고
    • Allergen challenge of lung tissue from asthmatics elicits bronchial constriction that correlates with the release of leukotrienes C4, D4, and E4
    • 14 Dahlen SE, Hannson G, Hedqvist P, et al. Allergen challenge of lung tissue from asthmatics elicits bronchial constriction that correlates with the release of leukotrienes C4, D4, and E4. Proc Natl Acad Sci USA 1983; 80: 1712-16.
    • (1983) Proc Natl Acad Sci USA , vol.80 , pp. 1712-1716
    • Dahlen, S.E.1    Hannson, G.2    Hedqvist, P.3
  • 15
    • 0027369276 scopus 로고
    • The effect of inhibition of 5-lipoxygenase by zileuton in mild to moderate asthma
    • 15 Israel E, Rubin P, Kemp JP, et al. The effect of inhibition of 5-lipoxygenase by zileuton in mild to moderate asthma. Ann Intern Med 1993; 119: 1059-66.
    • (1993) Ann Intern Med , vol.119 , pp. 1059-1066
    • Israel, E.1    Rubin, P.2    Kemp, J.P.3
  • 16
    • 0025685169 scopus 로고
    • Reduced allergen-induced nasal congestion and leukotriene synthesis with an orally active 5-lipoxygenase inhibitor
    • 16 Knapp HR. Reduced allergen-induced nasal congestion and leukotriene synthesis with an orally active 5-lipoxygenase inhibitor. N Engl J Med 1990; 323: 1745-48.
    • (1990) N Engl J Med , vol.323 , pp. 1745-1748
    • Knapp, H.R.1
  • 17
    • 0026459721 scopus 로고
    • Zileuton, a 5-lipoxygenase inhibitor in rheumatoid arthritis
    • 17 Weinblatt ME, Kremer JM, Coblyn JS, et al. Zileuton, a 5-lipoxygenase inhibitor in rheumatoid arthritis. J Rheumatol 1992; 19: 1537-41.
    • (1992) J Rheumatol , vol.19 , pp. 1537-1541
    • Weinblatt, M.E.1    Kremer, J.M.2    Coblyn, J.S.3
  • 18
    • 0028933151 scopus 로고
    • A pilot study of zileuton, a novel selective 5-lipoxygenase inhibitor, in patients with systemic lupus erythematosus
    • 18 Hackshaw KV, Shi Y, Brandwein SR, et al. A pilot study of zileuton, a novel selective 5-lipoxygenase inhibitor, in patients with systemic lupus erythematosus. J Rheumatol 1995; 22: 462-68.
    • (1995) J Rheumatol , vol.22 , pp. 462-468
    • Hackshaw, K.V.1    Shi, Y.2    Brandwein, S.R.3
  • 19
    • 0027340363 scopus 로고
    • Leukotriene E4 and granulocyte infiltration into asthmatic airways
    • 19 Laitinen LA, Laitinen A, Haahtela T, et al. Leukotriene E4 and granulocyte infiltration into asthmatic airways. Lancet 1993; 341: 989-90.
    • (1993) Lancet , vol.341 , pp. 989-990
    • Laitinen, L.A.1    Laitinen, A.2    Haahtela, T.3
  • 20
    • 0025735202 scopus 로고
    • The role of leukotriene antagonists and inhibitors in the treatment of airway disease
    • 20 Busse WW, Gaddy JN. The role of leukotriene antagonists and inhibitors in the treatment of airway disease. Am Rev Respir Dis 1991; 143: S103-07.
    • (1991) Am Rev Respir Dis , vol.143
    • Busse, W.W.1    Gaddy, J.N.2
  • 21
    • 0025021789 scopus 로고
    • Identification and isolation of a membrane protein necessary for leukotriene production
    • 21 Miller DK, Gillard JW, Vickers PJ, et al. Identification and isolation of a membrane protein necessary for leukotriene production. Nature 1990; 343: 278-81.
    • (1990) Nature , vol.343 , pp. 278-281
    • Miller, D.K.1    Gillard, J.W.2    Vickers, P.J.3
  • 22
    • 0023177955 scopus 로고
    • Leukotrienes and lipoxins: Structures, biosynthesis, and biological effects
    • 22 Samuelsson B, Dahlen SE, Lindgren JA, et al. Leukotrienes and lipoxins: structures, biosynthesis, and biological effects. Science 1987; 237: 1171-76.
    • (1987) Science , vol.237 , pp. 1171-1176
    • Samuelsson, B.1    Dahlen, S.E.2    Lindgren, J.A.3
  • 23
    • 0022378008 scopus 로고
    • In vivo metabolism of leukotriene C4 in man: Urinary excretion of leukotriene E4
    • 23 Orning L, Kaijser L, Hammerstrom S. In vivo metabolism of leukotriene C4 in man: urinary excretion of leukotriene E4. Biochem Biophys Res Commun 1985; 130: 214-20.
    • (1985) Biochem Biophys Res Commun , vol.130 , pp. 214-220
    • Orning, L.1    Kaijser, L.2    Hammerstrom, S.3
  • 24
    • 0022346874 scopus 로고
    • Identification and characterization of leukotriene D4 receptors in adult and fetal human lung
    • 24 Lewis MA, Mong S, Vessella RL, et al. Identification and characterization of leukotriene D4 receptors in adult and fetal human lung. Biochem Pharmacol 1985; 34: 3411-17.
    • (1985) Biochem Pharmacol , vol.34 , pp. 3411-3417
    • Lewis, M.A.1    Mong, S.2    Vessella, R.L.3
  • 25
    • 0026517149 scopus 로고
    • The discovery and development of zileuton: An orally active 5-lipoxygenase inhibitor
    • 25 Bell RL, Young PR, Albert D, et al. The discovery and development of zileuton: an orally active 5-lipoxygenase inhibitor. Int J Immunopharmacol 1992; 14: 505-10.
    • (1992) Int J Immunopharmacol , vol.14 , pp. 505-510
    • Bell, R.L.1    Young, P.R.2    Albert, D.3
  • 26
    • 0026332275 scopus 로고
    • Pharmacokinetics, safety, and ability to diminish leukotriene synthesis by zileuton, an inhibitor of 5-lipoxygenase
    • 26 Rubin P, Dubé L, Braeckman R, et al. Pharmacokinetics, safety, and ability to diminish leukotriene synthesis by zileuton, an inhibitor of 5-lipoxygenase. AAS 1991; 35: 103-16.
    • (1991) AAS , vol.35 , pp. 103-116
    • Rubin, P.1    Dubé, L.2    Braeckman, R.3
  • 27
    • 0028896856 scopus 로고
    • Stereoselective glucuronidation of zileuton isomers by human hepatic microsomes
    • 27 Sweeny DJ, Nellans HN. Stereoselective glucuronidation of zileuton isomers by human hepatic microsomes. Drug Metab Disp 1995; 23: 149-53.
    • (1995) Drug Metab Disp , vol.23 , pp. 149-153
    • Sweeny, D.J.1    Nellans, H.N.2
  • 28
    • 0025647031 scopus 로고
    • The effects of a 5-lipoxygenase inhibitor on asthma induced by cold, dry air
    • 28 Israel E, Dermarkarian R, Rosenberg M, et al. The effects of a 5-lipoxygenase inhibitor on asthma induced by cold, dry air. N Engl J Med 1990; 323: 1740-44.
    • (1990) N Engl J Med , vol.323 , pp. 1740-1744
    • Israel, E.1    Dermarkarian, R.2    Rosenberg, M.3
  • 29
    • 0029113871 scopus 로고
    • Effect of chronic 5-lipoxygenase inhibition on airway hyperresponsiveness in asthmatic subjects
    • 29 Fischer AR, McFadden CA, Frantz R, et al. Effect of chronic 5-lipoxygenase inhibition on airway hyperresponsiveness in asthmatic subjects. Am J Respir Crit Care Med 1995; 152: 1203-07.
    • (1995) Am J Respir Crit Care Med , vol.152 , pp. 1203-1207
    • Fischer, A.R.1    McFadden, C.A.2    Frantz, R.3
  • 30
    • 0026078163 scopus 로고
    • Effect of a 5-lipoxygenase inhibitor on leukotriene generation and airway responses after allergen challenge in asthmatic patients
    • 30 Hui KP, Taylor IK, Taylor GW, et al. Effect of a 5-lipoxygenase inhibitor on leukotriene generation and airway responses after allergen challenge in asthmatic patients. Thorax 1991; 46: 184-89.
    • (1991) Thorax , vol.46 , pp. 184-189
    • Hui, K.P.1    Taylor, I.K.2    Taylor, G.W.3
  • 31
    • 0026541707 scopus 로고
    • Mechanisms of aspirin sensitivity
    • 31 Lee TH. Mechanisms of aspirin sensitivity. Am Rev Respir Dis 1992; 145: 534-36.
    • (1992) Am Rev Respir Dis , vol.145 , pp. 534-536
    • Lee, T.H.1
  • 32
    • 0027762572 scopus 로고
    • The pivotal role of 5-lipoxygenase products in the reaction of aspirin-sensitive asthmatics to aspirin
    • 32 Israel E, Fischer AR, Rosenberg MA, et al. The pivotal role of 5-lipoxygenase products in the reaction of aspirin-sensitive asthmatics to aspirin. Am Rev Respir Dis 1993; 148: 1447-51.
    • (1993) Am Rev Respir Dis , vol.148 , pp. 1447-1451
    • Israel, E.1    Fischer, A.R.2    Rosenberg, M.A.3
  • 33
    • 0028643629 scopus 로고
    • Direct evidence for a role of the mast cell in the nasal response to aspirin in aspirin-sensitive asthma
    • 33 Fischer AR, Rosenberg MA, Lilly CM, et al. Direct evidence for a role of the mast cell in the nasal response to aspirin in aspirin-sensitive asthma. J Allergy Clin Immunol 1994; 94: 1046-56.
    • (1994) J Allergy Clin Immunol , vol.94 , pp. 1046-1056
    • Fischer, A.R.1    Rosenberg, M.A.2    Lilly, C.M.3
  • 34
    • 0029915834 scopus 로고    scopus 로고
    • Effect of treatment with zileuton, a 5-lipoxygenase inhibitor, in patients with asthma
    • 34 Israel E, Cohn J, Dubé L, et al. Effect of treatment with zileuton, a 5-lipoxygenase inhibitor, in patients with asthma. JAMA 1996; 275: 931-36.
    • (1996) JAMA , vol.275 , pp. 931-936
    • Israel, E.1    Cohn, J.2    Dubé, L.3
  • 35
  • 36
    • 0029123159 scopus 로고
    • Effect of 5-lipoxygenase inhibition on bronchoconstriction and airway inflammation in nocturnal asthma
    • 36 Wenzel SE, Trudeau JB, Kaminsky DA, et al. Effect of 5-lipoxygenase inhibition on bronchoconstriction and airway inflammation in nocturnal asthma. Am J Respir Crit Care Med 1995; 152: 897-905.
    • (1995) Am J Respir Crit Care Med , vol.152 , pp. 897-905
    • Wenzel, S.E.1    Trudeau, J.B.2    Kaminsky, D.A.3
  • 37
    • 0025349364 scopus 로고
    • Selective 5-lipoxygenase inhibition in ulcerative colitis
    • 37 Laursen LS, Naesdal J, Bukhave K, et al. Selective 5-lipoxygenase inhibition in ulcerative colitis. Lancet 1990; 335: 683-85.
    • (1990) Lancet , vol.335 , pp. 683-685
    • Laursen, L.S.1    Naesdal, J.2    Bukhave, K.3
  • 38
    • 0028914603 scopus 로고
    • The effect of zileuton on antipyrine and indocyanine green disposition
    • 38 St Peter JV, Braeckman RA, Granneman GR, et al. The effect of zileuton on antipyrine and indocyanine green disposition. Clin Pharmacol Ther 1995; 57: 299-308.
    • (1995) Clin Pharmacol Ther , vol.57 , pp. 299-308
    • St Peter, J.V.1    Braeckman, R.A.2    Granneman, G.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.