Ageing and the mismatch repair system

Mechanisms of Ageing and Development

Volumn 121, Issue 1-3, 2001, Pages 173-179

  Yehuda, Arie Ben ^a   Globerson, Amiela ^b   Krichevsky, Svetlana ^a   Bar On, Hanoch ^a   Kidron, Miriam ^a   Friedlander, Yechiel ^a   Friedman, Gideon ^a   Ben Yehuda, Dina ^a  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^b WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Aging; Microsatellite instability (MSI); Mismatch repair (MMR)

Indexed keywords

DNA BASE;

AGED; AGING; BASE MISPAIRING; CANCER SUSCEPTIBILITY; CARCINOGENESIS; COMPARATIVE STUDY; CORRELATION FUNCTION; DNA DAMAGE; DNA REPAIR; GENETIC STABILITY; HUMAN; IMMUNE SYSTEM; MICROSATELLITE INSTABILITY; PRIORITY JOURNAL; REVIEW;

EID: 0035915787     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0047-6374(00)00208-6     Document Type: Article

References (21)

1. DNA damage and mutation: Contributors to the age-related alterations in T cell-mediated immune responses?
2. Microsatellite instability and p53 mutations in therapy-related leukemia suggest imitator phenotype
3. Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyper-recombination and predisposition to cancer
4. Mismatch repair defects in human carcinogenesis
5. The human imitator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer
6. Loss of the wild type MLHI gene is a feature of HNPCC
7. Biochemistry and genetics of eukaryotic mismatch repair
8. Microsatellite instability: Marker of a mutator phenotype
9. Frameshift mutator mutations
10. Inactivation of the type 11 TGF-beta receptor in colon cancer cells with microsatellite instability
11. Mechanisms and biological effects of mismatch repair
12. Mutations of two PMS homologues in hereditary nonpolyposis colon cancer
13. Age-associated increase of spontaneous mutant frequency and molecular nature of mutation in new-born and old lacZ-transgenic mouse
14. Mutations of GTBP in genetically unstable cells
15. Mismatch repair deficiency in phenotypically normal human cells
16. Cancer of the microsatellite imitator phenotype
17. Hypermutation in IgV genes from mice deficient in the MLH I mismatch repair protein
18. Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite imitator phenotype
19. Base selection, proof reading and mismatch repair during DNA replication in E. coli
20. CpG island methylation phenotype in cororectal cancer
21. Abundant class of human DNA polymorphism which can be typed using the polymerase chain reaction