Differential Utilization of Enzyme-Substrate Interactions for Acylation but Not Deacylation during the Catalytic Cycle of Kex2 Protease

Journal of Biological Chemistry

Volumn 276, Issue 42, 2001, Pages 38394-38399

  Rockwell, Nathan C ^a,b,c   Fuller, Robert S ^a  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^b STANFORD UNIVERSITY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLATION; ESTERS; PHYSIOLOGY; SUBSTRATES;

BINDING;

ENZYMES;

AMIDE; ARGININE; ESTER; KEX2 PROTEINASE; LYSINE; PROTEINASE; SERINE PROTEINASE; SUBTILISIN; UNCLASSIFIED DRUG; FURIN; KEX2 PROTEIN, S CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEIN;

ACYLATION; AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CATALYSIS; DEACYLATION; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN PROCESSING; SACCHAROMYCES CEREVISIAE; STEADY STATE; BINDING SITE; CHEMICAL MODEL; CHEMISTRY; DOSE RESPONSE; ENZYMOLOGY; FLUOROMETRY; KINETICS; METABOLISM; PROTEIN BINDING;

EUKARYOTA; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

ACYLATION; ARGININE; BINDING SITES; CATALYSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; FLUOROMETRY; FURIN; KINETICS; LYSINE; MODELS, CHEMICAL; PROPROTEIN CONVERTASES; PROTEIN BINDING; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SUBSTRATE SPECIFICITY; SUBTILISINS;

EID: 0035914365     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M105782200     Document Type: Article

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