Alkyl-substituted silica gel as a carrier in the controlled release of dexmedetomidine

Journal of Controlled Release

Volumn 76, Issue 3, 2001, Pages 227-238

  Kortesuo, Pirjo ^a   Ahola, Manja ^b   Kangas, Minna ^b   Leino, Tiina ^a   Laakso, Sirpa ^a   Vuorilehto, Lauri ^a   Yli Urpo, Antti ^b   Kiesvaara, Juha ^a   Marvola, Martti ^c  

^a ORION CORPORATION   (Finland)

^b UNIVERSITY OF TURKU   (Finland)

^c UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Alkyl substituted silica xerogel; Dexmedetomidine; In vivo; Sol gel processed silica xerogel

Indexed keywords

DEXMEDETOMIDINE; DIMETHYLDIETHOXYSILANE; DRUG CARRIER; SILANE DERIVATIVE; SILICA GEL; SILICATE; TETRAETHOXYSILANE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED DRUG RELEASE; DOG; DOSE RESPONSE; DOSE TIME EFFECT RELATION; DRUG DEGRADATION; DRUG FORMULATION; DRUG SCREENING; DRUG STRUCTURE; PRIORITY JOURNAL; SUSTAINED DRUG RELEASE;

ALKYLATION; ANIMALS; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; DELAYED-ACTION PREPARATIONS; DEXMEDETOMIDINE; DOGS; DRUG CARRIERS; DRUG IMPLANTS; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; PARTICLE SIZE; SILICON DIOXIDE; SOLUBILITY;

EID: 0035914223     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(01)00428-X     Document Type: Article

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