In vitro behavior of silica-based xerogels intended as controlled release carriers

Journal of the American Ceramic Society

Volumn 82, Issue 4, 1999, Pages 969-976

  Falaize, Sylvie ^a   Radin, Shulamit ^a   Ducheyne, Paul ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BODY FLUIDS; CALCIUM; COMPOSITION EFFECTS; DIFFUSION IN LIQUIDS; DISSOLUTION; ELECTROLYTES; FLOW OF FLUIDS; HYDROGEN PEROXIDE; IMPLANTS (SURGICAL); PARTICLE SIZE ANALYSIS; PHOSPHORUS; PROTEINS;

XEROGEL;

SILICA GEL;

EID: 0032637428     PISSN: 00027820     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1151-2916.1999.tb01861.x     Document Type: Article

References (30)

1. C. W. Norden, "Antibiotic Prophylaxis in Orthopedic Surgery," Rev. Infect. Dis., 13 [Suppl. 10] S842-S846 (1991).
2. C. N. Cornell and J. M. Lane, "Newest Factors in Fracture Healing," Clin. Orthop., 277, 297-311 (1992).
3. L. A. Whiteside, "Treatment of Infected Total Knee Arthroplasty," Clin. Orthop., 299, 169-72 (1994).
4. M. J. Kraay, V. M. Goldberg, and H. E. Figgie, "Use of an Antibiotic-Impregnated Polymethyl Methacrylate Intramedullary Spacer for Complicated Revision Total Hip Arthroplasty," J. Arthroplasty, 7 (Suppl.) 397-402 (1992).
5. C. N. Cornell, D. Tyndall, S. Waller, J. M. Lane, and B. D. Brause, "Treatment of Experimental Osteomyelitis with Antibiotic-Impregnated Bone Graft Substitute," J. Orthop. Res., 11 [5] 619-26 (1995).
6. W. R. Gombotz, S. C. Pankey, L. S. Bouchard, D. H. Phan, and P. A. Poulakkainen, "Stimulation of Bone Healing by Transforming Growth Factor -Beta 1 Released from Polymeric or Ceramic Implants," J. Appl. Biomater., 5, 141-50 (1994).
7. S. Radin, P. Ducheyne, and T. Kamplain, "A Novel Xerogel Carrier for Controlled Release of Biologically Active Molecules: I, Antibiotics (Vancomycin)" (Abstract), Trans. Soc. Biomater., 21, 289 (1995).
8. S. B. Nicoll, S. Radin, E. M. Santos, R. S. Tuan, and P. Ducheyne, "In Vitro Release Kinetics of Biologically Active Transforming Growth Factor β 1 from a Novel Xerogel Carrier," Biomaterials, 18, 853-59 (1997).
9. E. M. Santos, S. Radin, and P. Ducheyne, "Bioactivity of a Sol - Gel-Derived Material for the Controlled Release of Growth Factors" (Abstract), Transactions of Fifth World Biomaterials Congress (Toronto, Canada, 1996).
10. L. L. Hench, "Bioceramics: From Concept to Clinic," J. Am. Ceram. Soc., 74 [7] 1487-510 (1991).
11. J. E. Geraci and P. E. Hermans, "Vancomycin," Mayo Clin. Proc., 58, 88-91 (1983).
12. S. R. Radin and P. Ducheyne, "The Effect of Calcium Phosphate Ceramic Composition and Structure on in Vitro Behavior. II. Precipitation," J. Biomed. Mater. Res., 27, 35-45 (1993).
13. T. Rae, "Cell Biochemistry in Relation to the Inflammatory Response to Foreign Materials"; pp. 159-81 in Fundamental Aspects of Biocompatibility, Vol. 8. Edited by D. F. Williams. CRC Press, Boca Raton, FL, 1981.
14. P. Tengvall, I. Lundstrom, L. Sjoqvist, H. Elwing, and L. M. Bjursten, "Titanium-Hydrogen Peroxide Interaction: Model Studies of the Influence of the Inflammatory Response on Titanium Implants," Biomaterials, 10 [3] 166-75 (1989).
15. B. J. Tyler and B. D. Ratner, "Variations between Biomer Lots. 2: The Effect of Differences between Lots on in Vitro Enzymatic and Oxidative Degradation of a Commercial Polyurethane," J. Biomed. Mater. Res., 27, 327-34 (1993).
16. 2 Test System for in Vitro Evaluation of Biodegradable Stress Cracking in Polyurethane Elastomers," J. Biomed. Mater. Res., 29, 467-75 (1995).
17. K. E. Healy and P. Ducheyne, "The Mechanisms of Passive Dissolution of Titanium in a Model Physiological Environment," J. Biomed. Mater. Res., 26 [3] 319 (1992).
18. J. K. Heinonen and R. J. Lahti, "A New and Convenient Colorimetric Determination of Inorganic Orthophosphate and Its Application to the Assay of Inorganic Pyrophosphate," Anal. Biochem., 113, 313-17 (1981).
19. C. J. Brinker and G. Scherer, Sol - Gel Science: The Physics and Chemistry of Sol - Gel Processing; pp. 541-46. Academic Press, San Diego, CA, 1990.
20. J. Y. Ying and J. B. Benziger, "Structural Evolution of Alkoxide Silica Gels to Glass: Effect of Catalyst pH," J. Am. Ceram. Soc., 76 [10] 2571-82 (1993).
21. G. H. Nancollas, "In Vitro Studies of Calcium Phosphate Crystallisation"; pp. 157-88 in Biomineralization: Chemical and Biomedical Perspectives. Edited by S. Mann, S. Webb, and B. J. P. Williams. VCH Verlagsgesellschraft, Weinheim, Germany, 1989.
22. G. Pannetier and P. Souchay, Chemical Kinetics, pp. 416-17. Elsevier, Amsterdam, The Netherlands, 1980.
23. T. L. O'Connor and S. A. Greenberg, "The Kinetics for the Solution of Silica in Aqueous Solutions," J. Phys. Chem., 62, 1195-98 (1958).
24. R. K. Iler, The Chemistry of Silica: Solubility, Polymerization, Colloid, and Surface Properties, and Biochemistry. Wiley, New York, 1979.
25. 2 on the Alkali-Silica Reaction," J. Am. Ceram. Soc., 77 [6] 1522-24 (1994).
26. J. D. Wiley, "Aging of Amorphous Silica in Salt Water Solutions"; pp. 149-64 in Soluble Silicates, Vol. 10. Edited by J. S. Falcone. American Chemical Society, Washington, DC, 1982.
27. M. M. Pereira, A. E. Clark, and L. L. Hench, "Calcium Phosphate Formation on Sol - Gel-Derived Bioactive Glasses in vitro," J. Biomed. Mater. Res., 28, 693-98 (1994).
28. P. J. Li, C. Ohtsuki, T. Kokubo, K. Nakanishi, N. Soga, T. Nakamura, and T. Yamamuro, "Apatite Formation Induced by Silica-Gel in a Simulated Body-Fluid," J. Am. Ceram. Soc., 75, 2094-97 (1992).
29. P. Ducheyne, S. Radin, and K. Ishikawa, "The Rate of Calcium Phosphate Precipitation on Metal and Ceramics, and the Relationship to Bioactivity"; pp. 213-18 in Bone-Bonding Materials. Edited by P. Ducheyne, T. Kokubo, and C. A. van Blitterswijk. Reed Healthcare Communications, The Netherlands, 1993.
30. E. Schepers, M. Declercq, P. Ducheyne, and R. Kempeneers, "Bioactive Glass Particulate Material as a Filler for Bone Lesions," Oral Rehabil., 18, 439-52 (1991).