Delayed induction of p38 MAPKs in reactive astrocytes in the brain of mice after KA-induced seizure

Molecular Brain Research

Volumn 94, Issue 1-2, 2001, Pages 157-165

  Che, Yongzhe ^a   Yu, Young Mi ^a   Han, Pyung Lim ^b   Lee, Ja Kyeong ^a  

^a Inha University School of Medicine   (South Korea)

^b Ewha Womans University School of Medicine   (South Korea)

Author keywords

Astrocyte; Delayed neuronal death; Gliosis; p38 MAPK; Status epilepticus

Indexed keywords

7 NITROINDAZOLE; ARGININE; ISOPROTEIN; KAINIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE SYNTHASE INHIBITOR; SYNAPTOPHYSIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; ASTROCYTOSIS; CELL LOSS; CELLULAR DISTRIBUTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG INDUCED DISEASE; ENZYME INDUCTION; HIPPOCAMPUS; IMMUNOREACTIVITY; MALE; MOUSE; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; SEIZURE;

ANIMALS; ANTIBODY SPECIFICITY; ASTROCYTES; BEHAVIOR, ANIMAL; CELL DEATH; EXCITATORY AMINO ACID AGONISTS; GLIOSIS; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; KAINIC ACID; MALE; MICE; MICE, INBRED BALB C; MITOGEN-ACTIVATED PROTEIN KINASES; NEURONS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; STATUS EPILEPTICUS;

EID: 0035914187     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(01)00233-9     Document Type: Article

References (31)

1. Determination of kainic acid-induced release of nitric oxide using a novel hemoglobin trapping technique with microdialysis
2. Nitric oxide superoxide, and peroxynitrite: The good, the bad and the ugly
3. Electrographic, clinical and pathological alterations following systemic administration of kainic acid, bicuculline or pentetrazole: Metabolic mapping using the deoxyglucose method with special reference to the pathology of epilepsy
4. The p38/ERK mitogen-activated protein kinase pathway regulates interleukin-6 synthesis response to tumor necrosis factor
5. Methods for antagonizing glutamate neurotoxicity
6. Neurotoxic action of kainic acid
7. Blockade of p38 mitogen-activated protein kinase pathway inhibits inducible nitric-oxide synthase expression in mouse astrocyte
8. Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures
9. Resistance to neurotoxicity in cortical cultures from neuronal nitric oxide synthase-deficient mice
10. p38 Kinase is activated in the Alzheimer's disease brain
11. p38 MAPK signaling cascades in inflammatory disease
12. Characterization of the structure and function of a new mitogen-activated protein kinase (p38β)
13. Microglial and astroglial reactions to ischemic and kainic acid-induced lesions of the rat hippocampus
14. Activation and involvement of p38 mitogen-activated protein kinase in glutamate-induced apoptosis in rat cerebellar granule cells
15. Apoptosis induced by withdrawal of trophic factors is mediated by p38 mitogen-activated protein kinase
16. Dynamic expression of SEK1 suggests multiple roles of the gene during embryogenesis and in adult brain of mice
17. Constitutive activity and Differential localization of p38 MAPKs in adult mouse brain
18. Proinflammatory cytokine-induced and chemical mediator-induced IL-8 expression in human bronchial epithelial cells through p38 mitogen-activated protein kinase-dependent pathway
19. Inhibition of neuronal (type 1) nitric oxide synthase prevents hyperaemia and hippocampal lesions resulting from kainate-induced seizures
20. Nitric oxide promotes seizure activity in kainate-treated rats
21. Astrocyte responses to CNS injury
22. Neuroprotective effects of 7-nitroindazole in the gerbil model of global cerebral ischemia
23. p38 mitogen activated protein kinase regulates endothelial VCAM-1 expression at the post-transcriptional level
24. Tumor necrosis factor alpha-induced E-selectin expression is activated by the nuclear factor-kappaB and c-Jun N-terminal kinase/p38 mitogen-activated protein kinase pathways
25. Involvement of free radicals in excitotoxicity in vivo
26. Kainic acid-induced seizure: Dose-relationship of behavioural, neurochemical and histopathological changes
27. Kainic acid-induced seizure: Neurochemical and histopathological changes
28. Kainic acid seizures in the rat
29. MAPK in microglia after ischemia
30. 2+: A novel ionic mediator of neural injury in brain disease
31. Opposing effects of ERK and JNK-p38 kinase MAP kinases on apoptosis