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Volumn 3, Issue 8, 2001, Pages 1133-1136

A novel traceless resin-bound guanidinylating reagent for secondary amines to prepare N,N-disubstituted guanidines

Author keywords

[No Author keywords available]

Indexed keywords

AMINE; GUANIDINE; GUANIDINE DERIVATIVE; URETHAN;

EID: 0035912357     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol015576n     Document Type: Article
Times cited : (47)

References (34)
  • 1
    • 0033936203 scopus 로고    scopus 로고
    • The list of cited references contains only very few examples of biologically active guanidine-containing molecules and is by no means complete, (a) Yamamoto, T.; Hori, M.; Watanabe, I.; Harada, K. Chem. Pharm. Bull. 2000, 48, 843-849.
    • (2000) Chem. Pharm. Bull. , vol.48 , pp. 843-849
    • Yamamoto, T.1    Hori, M.2    Watanabe, I.3    Harada, K.4
  • 13
    • 0041787953 scopus 로고    scopus 로고
    • note
    • The contents were found to be N 2.15%, S 1.47%, and F 2.88%. From these values, a loading of 0.49 mmol/g was deduced. Starting with a resin with an initial loading of 0.6 mmol/g, this loading represents an 89% yield over two steps.
  • 14
    • 0042790142 scopus 로고    scopus 로고
    • note
    • Primary aliphatic and aromatic amines can be quantitatively converted to the corresponding guanidines rapidly and in high purities. However, in this paper only secondary amines will be discussed.
  • 33
    • 0041787951 scopus 로고    scopus 로고
    • note
    • 2 146.0924, found 146.0919.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.