A novel solid-phase synthesis of highly diverse guanidines: Reactions of primary amines attached to the T2* linker

Organic Letters

Volumn 2, Issue 23, 2000, Pages 3563-3565

  Dahmen, Stefan ^a   Bräse, Stefan ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE; DIAZONIUM COMPOUND; GUANIDINE DERIVATIVE; RESIN; TRIAZENE DERIVATIVE;

ARTICLE; CHEMISTRY; SYNTHESIS;

AMINES; DIAZONIUM COMPOUNDS; GUANIDINES; RESINS, SYNTHETIC; TRIAZENES;

EID: 0034676628     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol006440c     Document Type: Article

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31. The compound was characterized by MS spectroscopy. As the formation of the dimeric compound on solid support is unlikely because of the moderate loading of the Merrifield resin used (0.93 mmol/g for the starting material), the dimerization has presumably taken place under the acidic cleavage conditions.
32. A strong anion-exchange resin (Lewatit MP 5080, Merck Darmstadt) was used in methanol.