Hsp70 and antifibrillogenic peptides promote degradation and inhibit intracellular aggregation of amyloidogenic light chains

Journal of Cell Biology

Volumn 152, Issue 4, 2001, Pages 705-715

  Dul, Jeanne L ^a   Davis, David P ^a   Williamson, Edward K ^a   Stevens, Fred J ^b   Argon, Yair ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b ARGONNE NATIONAL LABORATORY   (United States)

Author keywords

Amyloidosis; BiP; Fibril assembly; Immunoglobulin; Proteasome

Indexed keywords

HEAT SHOCK PROTEIN 70; IMMUNOGLOBULIN LIGHT CHAIN; PEPTIDE DERIVATIVE; PROTEASOME;

AMYLOIDOSIS; ANIMAL CELL; ARTICLE; BIOACCUMULATION; CELL STRAIN COS1; CONTROLLED STUDY; ELECTRON MICROSCOPY; ENDOPLASMIC RETICULUM; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; AMYLOIDOSIS; ANIMALS; BENCE JONES PROTEIN; CARRIER PROTEINS; CELL COMPARTMENTATION; COS CELLS; CYSTEINE ENDOPEPTIDASES; CYTOSOL; HEAT-SHOCK PROTEINS; HSP70 HEAT-SHOCK PROTEINS; IMMUNOGLOBULIN LIGHT CHAINS; MODELS, BIOLOGICAL; MOLECULAR CHAPERONES; MOLECULAR SEQUENCE DATA; MULTIENZYME COMPLEXES; MUTATION; ORGANELLES; PEPTIDES; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; SOLUBILITY;

ANIMALIA;

EID: 0035911163     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.152.4.705     Document Type: Article

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