Effects of atorvastatin and ω-3 fatty acids on LDL subfractions and postprandial hyperlipemia in patients with combined hyperlipemia

Nutrition, Metabolism and Cardiovascular Diseases

Volumn 11, Issue 1, 2001, Pages 7-16

  Nordoy A ^a   Hansen, J B ^a   Brox, J ^a   Svensson, B ^a  

^a UNIVERSITY OF TROMSØ   (Norway)

Author keywords

3 fatty acids; Hyperlipemia; LDL subfraction; Statins

Indexed keywords

APOLIPOPROTEIN; ATORVASTATIN; HEPTANOIC ACID DERIVATIVE; HYPOCHOLESTEROLEMIC AGENT; LOW DENSITY LIPOPROTEIN CHOLESTEROL; OMEGA 3 FATTY ACID; PYRROLE DERIVATIVE; TRIACYLGLYCEROL;

ADULT; ARTICLE; BLOOD; BLOOD PRESSURE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG POTENTIATION; FAMILIAL HYPERLIPEMIA; FEMALE; HUMAN; MALE; MIDDLE AGED; POSTPRANDIAL STATE; RANDOMIZED CONTROLLED TRIAL;

ADULT; ANTICHOLESTEREMIC AGENTS; APOLIPOPROTEINS; BLOOD PRESSURE; CHOLESTEROL, LDL; DOUBLE-BLIND METHOD; DRUG SYNERGISM; FATTY ACIDS, OMEGA-3; FEMALE; HEPTANOIC ACIDS; HUMANS; HYPERLIPIDEMIA, FAMILIAL COMBINED; MALE; MIDDLE AGED; POSTPRANDIAL PERIOD; PYRROLES; TRIGLYCERIDES;

EID: 0142036925     PISSN: 09394753     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. Carlson LA, Bøttiger LE (1985) Risk factors for ischemic heart disease in men and women. Results of the 19-year follow up of the Stockholm preventive study. Acta Med Scand 218: 207-211
2. Castelli WP, Garrison RJ, Wilson PW, Abbott RD, Kalousdian S, Kannel WB (1986) Incidence of coronary heart disease and lipoprotein cholesterol levels. The Framingham study. JAMA 256: 2835-2838
3. Jeppesen J, Hein HO, Suandicani P, Gycetalberg F (1997) Relationship of high TG-low HDL and LDL cholesterol to the incidence of ischemic heart disease. An 8-year follow up in the Copenhagen male study. Arterioscl Thromb Vasc Biol 17: 1114-1120
4. Stampfer MJ, Krauss RM, Ma J, Blanche PJ, Holl LG, Sacks FM, Hennekens CH (1996) A prospective study of triglyceride level, low-density lipoprotein particle diameter and risk of myocardial infarction. JAMA 276: 882-888
5. Manninen V, Tenkanen L, Korshinen P, Huttunen JK, Manttari M, Heinonen OP, Frick MH (1992) Joint effects of serum triglyceride and LDL cholesterol and HDL cholesterol concentrations on coronary heart disease risk in the Helsinki Heart Study: implications for treatment. Circulation 85: 3745-3752
6. Assmann G, Schultz H (1992) Relation of high density lipoprotein cholesterol and triglycerides to incidence of coronary artery disease: the PROCAM experience. Am J Cardiol 20: 733-737
7. Lamarche B, Despoes JP, Moorjami S, Canten B, Dagenais GR, Lupien PJ (1996) Triglycerides and HDL cholesterol as risk factors for ischemic heart diseases: results form the Quebec Cardiovascular Study. Atherosclerosis 119: 235-245
8. Lamarche B, Tchernof A, Moorjani S, Cantin B, Dagenais GR, Lupien PS, Despres JP (1997) Small dense, low-density lipoprotein particles as a predictor of the risk of ischemic heart disease in men. Circulation 95: 69-75
9. Reaven GM (1988) Banting lecture 1988; role of insulin resistance in human disease. Diabetes 37: 1595-1607
10. Harris WS (1989) Fish oils and plasma lipid and lipoprotein metabolism in humans: a critical review. J Lipid Res 30: 785-807
11. Nordøy A, Hatcher L, Ullmann DL, Connor WE (1993) Individual effects of dietary saturated fatty acids and fish oil on plasma lipids and lipoproteins in normal men. Am J Clin Nutr 57: 634-639
12. Yu-Poth S, Zhao G, Etherton T, Naglak M, Jonnalagadda S, Kvis-Etherton PM (1999) Effects of the National Cholesterol Education Program on cardiovascular disease risk factors: a metaanalysis. Am J Clin Nutr 69: 632-646
13. Bignen FCH, Festkens EJM, Caspersen CJ, Nagelkerke N, Mosterd WL, Kromhout D (1999) Baseline and previous physical activity in relation to mortality in elderly men. Am J Epidemiol 150: 1289-1296
14. Nordøy A, Bønaa KH, Nilsen H, Hansen JB, Ingebretsen OC (1998) Effects of simvastatin and omega-3 fatty acids on plasma lipoproteins and lipid peroxidation in patients with combined hyperlipidemia. J Intern Med 243: 163-170
15. Nordøy A, Bønaa KH, Sandset PM, Hansen JB, Nilsen H (2000) Effect of ω-3 fatty acids and simvastatin on hemostatic risk factors and postprandial hyperlipemia in patients with combined hyperlipemia. Arterioscler Thromb Vasc Biol 20: 259-265
16. Marckmann P, Grønbæk M (1999) Fish consumption and coronary heart disease mortality. A systematic review of prospective cohort studies. Eur J Clin Nutr 53: 585-590
17. Burr ML, Fehily AM, Gilbert JF, Rogers S, Holliday RM, Sweetnam PM, Elevood PC, Deadman NM (1989) Effects of changes in fat, fish and fibre intakes on death and myocardial reinfarction: diet and reinfarction trial (DART) Lancet ii: 757-761
18. GISSI-PrevenzioneInvestigators (1999) Dietary supplementation with ω-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Lancet ii: 447-455
19. Dart A, Jerums G, Nicholson G, d'Emden M, Hamilton-Craig I, Tallis G, Best J, West M, Sullivan D, Bracs P, Black D, (1997) A multicenter, double-blind, one-year study comparing safety and efficacy of atorvastatin versus simvastatin in patients with hypercholesterolemia. Am J Cardiol 80: 39-44
20. Redgrave TG, Roberts DC, West CE (1975) Separation of plasma lipoproteins by density-gradient ultracentrifugation. Ann Biochem 65: 42-49
21. Griffin BA, Caslake MJ, Yip B, Tait GW, Packard CJ, Sheperd J (1990) Rapid isolation of low density lipoprotein (LDL) subfractions from plasma by density gradient ultracentrifugation. Atherosclerosis 83: 59-67
22. Bengtsson Olivecrona G, Olivecrona T (1992) Assay of lipoprotein lipase and hepatic lipase in Lipoprotein analysis: a practical approach. In: Carolyn A, Converse E. Skinner R (Eds), IRL Press, Oxford, pp 169-185
23. Patch JR, Karlin JR, Scott LW, Smith C, Gotto A (1983) Inverse relationship between blood levels of high density lipoproteins and magnitude of postprandial lipemia. Proc Natl Acad Sci USA 80: 1449-1453
24. SAS Institute Inc. (1987) SAS/STAT Guide for personal computers, Version 6. Cory, NC:SAS Institute Inc
25. Hansen JB, Lyngmo V, Svensson B, Nordøy A (1993) Inhibition of exercise induced shortening of bleeding time by fish oil in familial hypercholesterolemia. Arterioscler Thromb 1: 98-104
26. Contacos C, Barker P, Sullivan DR (1993) Effect of pravastatin and ω-3 fatty acids on plasma lipids and lipoproteins in patients with combined hyperlipidemia. Arterioscler Thromb 13: 1755-1762
27. Baumstark MW, Frey I, Berg A, Keul J (1992) Influence of n-3 fatty acids from fish oils on concentration of high- and low density lipoprotein subfractions and their lipid and apolipoprotein composition. Clin Biochem 25: 338-340
28. Suzukawa M, Abbey M, Horve PRC, Nestel PJ (1995) Effects of fish oil fatty acids on low density lipoprotein size, oxidability, and uptake by macrophages. J Lipid Res 36: 473-482
29. Hoogerbrugge N, Jansen H (1999) Atorvastatin increases low-density lipoprotein size and enhances high-density lipoprotein cholesterol concentration in male, but not in female patients with familial hypercholesterolemia. Atherosclerosis 146: 167-174
30. Gurrin M, Lassel TS, LeGoff W, Farnier M, Chapman MJ (2000) Action of atorvastatin in combined hyperlipemia. Arterioscler Thromb Vasc Biol 20: 189-196
31. Simonsen T, Nordøy A, Sjunneskog C, Lyngmo V (1988) The effect of cod liver oil in two populations with low and high intake of dietary fish. Acta Med Scand 223: 491-498
32. Harris WS, Connor WE, Alam N, Illingworth PR (1988) Reduction of postprandial triglyceridemia in humans by dietary n-3 fatty acids. J Lipid Res 29: 1451-1460
33. Marckmann P, Bladbjerg EM, Jespersen J (1997) Dietary fish oil (4 g daily) and cardiovascular risk (markers) in healthy men. Arterioscler Thromb Vasc Biol 17: 3384-3391
34. Nestel PJ, Connor WE, Reandon MF, Connor S, Wong S, Boston R (1984) Suppression by diets rich in fish oil of very low density lipoprotein production in man. J Clin Invest 74: 82-89
35. Weintraub MS, Zechner R, Brown A, Eisenberg S, Breslow JL (1988) Dietary polyunsaturated fatty acids of the ω-3 series reduce postprandial lipoprotein levels. J Clin Invest 82: 1884-1893
36. Harris WS, Connor WE, Alam N, Illingworth PR (1997) Reduction of postprandial triglyceridemia in humans by dietary n-3 fatty acids. Am J Clin Nutr 66: 254-260
37. Harris WS, Hustvedt BE, Hagen E, Green MH, Lu GP, Drevon CA (1997) n-3 fatty acids in chylomicron metabolism in the rat. J Lipid Res 138: 503-515
38. Kasim-Karakas SE, Herrmann R, Alenario R (1995) Effects of omega-3 fatty acids on intravascular lipolysis of very low density lipoproteins in humans. Metabolism 44: 1223-1230
39. Minihane AM, Khan S, Leigh-Firbank EC, Talmud P, Wright JW, Murphy MC, Griffin BA, Williams CM (2000) Apo E polymorphism and fish oil supplementation in subjects with an atherogenic lipoprotein phenotype (ALP). Arterioscler Thromb Vasc Biol 20: 1990-1997