The Propeptide of the Transforming Growth Factor-β Superfamily Member, Macrophage Inhibitory Cytokine-1 (MIC-1), Is a Multifunctional Domain That Can Facilitate Protein Folding and Secretion

Journal of Biological Chemistry

Volumn 276, Issue 20, 2001, Pages 16911-16918

  Fairlie, W Douglas ^a   Zhang, Hong Ping ^a   Wu, Wan M ^a   Pankhurst, Susan L ^a   Bauskin, Asne R ^a   Russell, Patricia K ^a   Brown, Peter K ^a   Breit, Samuel N ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH KINETICS; MUTAGENESIS; PROTEINS;

COTRANSFECTION;

BIOCHEMISTRY;

CHIMERIC PROTEIN; INHIBITOR PROTEIN; MACROPHAGE INHIBITORY CYTOKINE 1; MUTANT PROTEIN; PROPEPTIDE; PROTEIN PRECURSOR; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; ACTIVIN; BONE MORPHOGENETIC PROTEIN; CYTOKINE; HYBRID PROTEIN; INHIBIN; OSTEOGENIC PROTEIN 1; PLAB PROTEIN; PRIMER DNA;

ANIMAL CELL; ARTICLE; CHIMERA; CHO CELL; DELETION MUTANT; GENETIC TRANSFECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; PROTEIN SYNTHESIS; AMINO ACID SEQUENCE; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; GLYCOSYLATION; HAMSTER; HUMAN; METABOLISM; MOLECULAR GENETICS; MOUSE; PHYSIOLOGY; POLYMERASE CHAIN REACTION; PROTEIN PROCESSING; PROTEIN SECONDARY STRUCTURE;

ANIMALIA; MURINAE;

ACTIVINS; AMINO ACID SEQUENCE; ANIMALS; BONE MORPHOGENETIC PROTEINS; CHO CELLS; CRICETINAE; CYTOKINES; DNA PRIMERS; GLYCOSYLATION; HUMANS; INHIBINS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; PROTEIN FOLDING; PROTEIN PRECURSORS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT FUSION PROTEINS; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA;

EID: 0035907346     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M010000200     Document Type: Article

References (33)

1. Bootcov, M. R., Bauskin, A. R., Valenzuela, S. M., Moore, A. G., Bansal, M., He, X. Y., Zhang, H. P., Donnellan, M., Mahler, S., Pryor, K., Walsh, B. J., Nicholson, R. C., Fairlie, W. D., Por, S. B., Robbins, J. M., and Breit, S. N. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 11514-11519
2. Fairlie, W. D., Moore, A. G., Bauskin, A. R., Russell, P. K., Zhang, H. P., and Breit, S. N. (1999) J. Leukocyte Biol. 65, 2-5
3. Lawton, L. N., Bonaldo, M. F., Jelenc, P. C., Qiu, L., Baumes, S. A., Marcelino, R. A., de Jesus, G. M., Wellington, S., Knowles, J. A., Warburton, D., Brown, S., and Soares, M. B. (1997) Gene (Amst.) 203, 17-26
4. Paralkar, V. M., Vail, A. L., Grasser, W. A., Brown, T. A., Xu, H., Vukicevic, S., Ke, H. Z., Qi, H., Owen, T. A., and Thompson, D. D. (1998) J. Biol. Chem. 273, 13760-13767
5. Bottner, M., Suter-Crazzolara, C., Schober, A., and Unsicker, K. (1999) Cell Tissue Res. 297, 103-110
6. Hromas, R., Hufford, M., Sutton, J., Xu, D., Li, Y., and Lu, L. (1997) Biochim. Biophys. Acta 1354, 40-44
7. Yokoyama-Kobayashi, M., Saeki, M., Sekine, S., and Kato, S. (1997) J. Biochem. (Tokyo) 122, 622-626
8. Moore, A. G., Brown, D. A., Fairlie, W. D., Bauskin, A. R., Brown, P. K., Munier, M. L. C., Russell, P. K., Salmonsen, L. A., Wallace, E. M., and Breit, S. N. (2000) J. Clin. Endrinol. Metab., 85, 4781-4789
9. Li, P.-X., Wong, J., Ayed, A., Duc, N., Brade, A. M., Arrowsmith, C., Austin, R. C., and Klamutt, H. J. (2000) J. Biol. Chem. 275, 20127-20135
10. Tan, M., Wang, Y., Guan, K., and Sun, Y. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 109-114
11. Kannan, K., Amariglio, N., Rechavi, G., and Givol, D. (2000) FEBS Lett. 470, 77-82
12. Bauskin, A. R., Zhang, H.-P., Fairlie, W. D., Russell, P. K., Moore, A. G., Brown, D. A., Stanley, K. K., and Breit, S. N. (2000) EMBO J. 19, 2212-2220
13. Fairlie, W. D., Zhang, H.-P., Brown, P. K., Russell, P. K., Bauskin, A. R., and Breit, S. N. (2000) Gene (Amst.) 254, 67-76
14. Wilson, C. A., di Clemente, N., Ehrenfels, C., Pepinsky, R. B., Josso, N., Vigier, B., and Cate, R. L. (1993) Mol. Endocrinol. 7, 247-257
15. Israel, D. I., Nove, J., Kerns, K. M., Moutsatsos, I. K., and Kaufman, R. J. (1992) Growth Factors 7, 139-150
16. Gray, A. M., and Mason, A. J. (1990) Science 247, 1328-1330
17. Sha, X., Yang, L., and Gentry, L. E. (1991) J. Cell Biol. 114, 827-839
18. Brunner, A. M., Lioubin, M. N., Marquardt, H., Malacko, A. R., Wang, W. C., Shapiro, R. A., Neubauer, M., Cook, J., Madisen, L., and Purchio, A. F. (1992) Mol. Endocrinol. 6, 1691-1700
19. Lopez, A. R., Cook, J., Deininger, P. L., and Derynck, R. (1992) Mol. Cell. Biol. 12, 1674-1679
20. Brunner, A. M., Marquardt, H., Malacko, A. R., Lioubin, M. N., and Purchio, A. F. (1989) J. Biol. Chem. 264, 13660-13664
21. Mason, A. J. (1994) Mol. Endocrinol. 8, 325-332
22. Amatayakul-Chantler, S., Qian, S. W., Gakenheimer, K., Bottinger, E. P., Roberts, A. B., and Sporn, M. B. (1994) J. Biol. Chem. 269, 27687-27691
23. Fairlie, W. D., Russell, P. K., Wu, W. M., Moore, A. G., Zhang, H.-P., Brown, P. K., Bauskin, A. R., and Breit, S. N. (2001) Biochemistry 40, 65-73
24. Griffith, D. L., Keck, P. C., Sampath, T. K., Rueger, D. C., and Carlson, W. D. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 878-883
25. Daopin, S., Piez, K. A., Ogawa, Y., and Davies, D. R. (1992) Science 257, 369-373
26. Hinck, A. P., Archer, S. J., Qian, S. W., Roberts, A. B., Sporn, M. B., Weatherbee, J. A., Tsang, M. L., Lucas, R., Zhang, B. L., Wenker, J., and Torchia, D. A. (1996) Biochemistry 35, 8517-8534
27. Mittl, P. R., Priestle, J. P., Cox, D. A., McMaster, G., Cerletti, N., and Grutter, M. G. (1996) Protein Sci. 5, 1261-1271
28. Scheufler, C., Sebald, W., and Hulsmeyer, M. (1999) J. Mol. Biol. 287, 103-115
29. Eigenbrot, C., and Gerber, N. (1997) Nat. Struct. Biol. 4, 435-438
30. Burmester, J. K., Qian, S. W., Ohlsen, D., Phan, S., Sporn, M. B., and Roberts, A. B. (1998) Growth Factors 15, 231-242
31. Burmester, J. K., Qian, S. W., Roberts, A. B., Huang, A., Amatayakul-Chantler, S., Suardet, L., Odartchenko, N., Madri, J. A., and Sporn, M. B. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 8628-8632
32. Strelau, J., Sullivan, A., Bottner, M., Lingor, P., Falkenstein, E., Suter-Crazzolara, C., Galter, D., Jaszai, J., Krieglstein, K., and Unsicker, K. (2000) J. Neurosci. 20, 8597-8603
33. Jones, W. K., Richmond, E. A., White, K., Sasak, H., Kusmik, W., Smart, J., Oppermann, H., Rueger, D. C., and Tucker, R. F. (1994) Growth Factors 11, 215-225