Structural Analyses of a Malate Dehydrogenase with a Variable Active Site

Journal of Biological Chemistry

Volumn 276, Issue 33, 2001, Pages 31156-31162

  Bell, Jessica K ^a   Yennawar, Hemant P ^b   Wright, S Kirk ^c,d   Thompson, James R ^a   Viola, Ronald E ^c   Banaszak, Leonard J ^a,e  

^a UNIVERSITY OF MINNESOTA   (United States)

^b PENNSYLVANIA STATE UNIVERSITY   (United States)

^c UNIVERSITY OF TOLEDO   (United States)

^d UNIVERSITY OF WISCONSIN MADISON   (United States)

^e 6 155 Jackson Hall ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CATALYSIS; GENETIC ENGINEERING; HYDROGEN BONDS; KETONES; MOLECULAR STRUCTURE; OXIDATION; STRUCTURAL ANALYSIS;

BINARY COMPLEXES; OXALOACETATE;

ENZYMES;

ARGININE; CARBOXYL GROUP; CARBOXYLIC ACID; GUANIDINE DERIVATIVE; HYDROXYL GROUP; KETONE; MALATE DEHYDROGENASE; NICOTINAMIDE ADENINE DINUCLEOTIDE; OXALOACETIC ACID; OXOACID; PYRUVIC ACID; SULFATE;

ARTICLE; BINDING SITE; CATALYSIS; CHEMICAL MODIFICATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME CONFORMATION; ENZYME SPECIFICITY; ENZYME STRUCTURE; HYDROGEN BOND; MOLECULAR MODEL; NONHUMAN; OXIDATION; PRIORITY JOURNAL; STRUCTURE ANALYSIS; X RAY ANALYSIS; AUDIOVISUAL EQUIPMENT; CHEMISTRY; CRYSTALLOGRAPHY; PROTEIN CONFORMATION;

BINDING SITES; CRYSTALLOGRAPHY; MALATE DEHYDROGENASE; MODELS, STRUCTURAL; NAD; PROTEIN CONFORMATION; PYRUVIC ACID;

EID: 0035903166     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M100902200     Document Type: Article

References (21)

1. Hall, M. D., and Banaszak, L. J. (1993) J. Mol. Biol. 232, 213-222
2. Chapman, A. D. M., Cortes, A., Dafforn, T. R., Clarke, A. R., and Brady, R. L. (1999) J. Mol. Biol. 285, 703-712
3. Birktoft, J. J., and Banaszak, L. J. (1983) J. Biol. Chem. 258, 472-482
4. Wilks, H. M., Hart, K. W., Feeney, R., Dunn, C. R., Muirhead, H., Chia, W. N., Barstow, D. A., Atkinson, T., Clarke, A. R., and Holbrook, J. J. (1988) Science 242, 1541-1544
5. Nicholls, D., Miller, J., Scawen, M., Clarke, A. R., Holbrook, J. J., Atkinson, T. and Goward, C. (1992) Biochem. Biophys. Res. Commun. 189, 1057-1062
6. Wright, S. K., and Viola, R. E. (2001) J. Biol. Chem. 276, 31151-31155
7. Hall, M., Levitt, D., McAlister-Henn, L., and Banaszak, L. J. (1991) J. Mol. Biol. 220, 551-553
8. Navaza, J. (1994) Acta Crystallogr. Sect. A 50, 157-163
9. Castellano, E., Oliva, G., and Navaza, J. (1992) J. Appl. Crystallogr. 25, 281-284
10. Brunger, A. T., Adams, P. D., Clore, G. M., Delano, W. L., Gros, P., Grossekunstleve, R. W., Jiang, J. S., Kuszewski, J., Nilges, M., Pannu, N. S., Read, R. J., Rice, L. M., Simonson, T., and Warren, G. L. (1998) Acta Crystallogr. Sect. D Biol. Crystallogr. 54, 905-921
11. Jones, T., Zou, J., Cowan, S., and Kjeldgaard, M. (1991) Acta Crystallogr. Sect. A 47, 110-119
12. Kleywegt, G. J., and Jones, T. A. (1998) Acta Crystallogr. Sect. D Biol. Crystallogr. 54, 1119-1131
13. Vriend, G. (1990) J. Mol. Graph. 8, 52-56
14. Rodriguez, R., Chinea, G., Lopez, N., Pons, T., and Vriend, G. (1998) Comput. Appl. Biosci. 14, 523-528
15. Laskowski, R., MacArthur, M., Moss, D., and Thornton, J. M. (1993) J. Appl. Crystallogr. 26, 283-291
16. Otwinowski, Z., and Minor, W. (1997) Methods Enzymol. 276, 307-326
17. Evans, S. V. (1993) J. Mol. Graph. 11, 134-138
18. Wright, S. K., Kish, M. M., and Viola, R. E. (2000) J. Biol. Chem. 275, 31689-31694
19. Hall, M., Levitt, D., and Banaszak, L. J. (1992) J. Mol. Biol. 226, 867-882
20. Birktoft, J. J., Rhodes, G., and Banaszak, L. J. (1989) Biochemistry 28, 6065-6081
21. Kabsch, W., and Sander, C. (1983) Biopolymers 22, 2577-2637