ErbB-4 activation inhibits apoptosis in PC12 cells

Neuroscience

Volumn 107, Issue 2, 2001, Pages 353-362

  Erlich, S ^a   Goldshmit, Y ^a   Lupowitz, Z ^a   Pinkas Kramarski, R ^a  

^a TEL AVIV UNIVERSITY   (Israel)

Author keywords

Epidermal growth factor; ErbB HER family; Neu differentiation factor; Neuregulin; Signal transduction; Tyrosine kinase

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 4; NERVE GROWTH FACTOR; NEU DIFFERENTIATION FACTOR; NEUROTROPHIC FACTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN; PROTEIN KINASE B; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL STRAIN; CELL SURVIVAL; CONTROLLED STUDY; NERVE CELL DIFFERENTIATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; RAT; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; APOPTOSIS; CELL SURVIVAL; CULTURE MEDIA, SERUM-FREE; EPIDERMAL GROWTH FACTOR; NERVE GROWTH FACTOR; NEUREGULINS; PC12 CELLS; PRECIPITIN TESTS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0035900613     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(01)00350-5     Document Type: Article

References (59)

1. The selective and inducible activation of endogenous PI 3-kinase in PC12 cells results in efficient NGF-mediated survival but defective neurite outgrowth
2. Trophic factors and neuronal survival
3. The neu oncogene encodes an epidermal growth factor receptor-related protein
4. Epidermal growth factor-related peptides activate distinct subsets of ErbB receptors and differ in their biological activities
5. Effects of GGF/neuregulins on neuronal survival and neurite outgrowth correlate with erbB2/neu expression in developing rat retina
6. Purification and preliminary characterization of a glial growth factor from the bovine pituitary
7. GGF/neuregulin is a neuronal signal that promotes the proliferation and survival and inhibits the differentiation of oligodendrocyte progenitors
8. Nerve growth factor prevents vinblastine destructive effects on sympathetic ganglia in newborn mice
9. Comparison of rapid changes in surface morphology and coated pit formation of PC12 cells in response to nerve growth factor, epidermal growth factor, and dibutyryl cyclic AMP
10. Aria, a protein that stimulates acetylcholine receptor synthesis, also induces tyrosine phosphorylation of a 185-kDa muscle transmembrane protein
11. + channels in cultured chick muscle is increased by ARIA, an acetylcholine receptor-inducing activity
12. Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene
13. Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells
14. Neu differentiation factor is a neuron-glia signal and regulates survival, proliferation, and maturation of rat Schwann cell precursors
15. Activation of HER4 by heparin-binding EGF-like growth factor stimulates chemotaxis but not proliferation
16. Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor
17. Nerve growth factor prevents the death and stimulates the neuronal differentiation of clonal PC12 pheochromocytoma cells in serum-free medium
18. Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor
19. Axonal interactions regulate Schwann cell apoptosis in developing peripheral nerve: Neuregulin receptors and the role of neuregulins
20. Nerve growth factor inhibits apoptosis induced by tumor necrosis factor in PC12 cells
21. Dimerization of cell surface receptors in signal transduction
22. Inhibitors of p38 mitogen-activated protein kinase promote neuronal survival in vitro
23. Nerve growth factor-induced alteration in the response of PC12 pheochromocytoma cells to epidermal growth factor
24. Nerve growth factor induces survival and differentiation through two distinct signaling cascades in PC12 cells
25. Isolation and characterization of ErbB-3, a third member of the ErbB/epidermal growth factor receptor family: Evidence for overexpression in a subset of human mammary tumors
26. Glial growth factors are alternatively spliced erbB-2 ligands expressed in the nervous system
27. Stimulation of neurite outgrowth in PC12 cells by EGF and KCl depolarization: A Ca(2+)-independent phenomenon
28. Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
29. Nerve growth factor withdrawal-induced cell death in neuronal PC12 cells resembles that in sympathetic neurons
30. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
31. Neural expression and chromosomal mapping of Neu differentiation factor to 8p12-p21
32. Roles of neuregulin in synaptogenesis between mossy fibers and cerebellar granule cells
33. Isolation of the neu/HER-2 stimulatory ligand: A 44 kd glycoprotein that induces differentiation of mammary tumor cells
34. Neu and its ligands: From an oncogene to neural factors
35. ErbB receptors and EGF-like ligands: Cell lineage determination and oncogenesis through combinatorial signaling
36. Differential expression of NDF/neuregulin receptors ErbB-3 and ErbB-4 and involvement in inhibition of neuronal differentiation
37. Brain neurons and glial cells express NDF/heregulin-a survival factor for astrocytes
38. Diversification of Neu differentiation factor and epidermal growth factor signaling by combinatorial receptor interactions
39. Structure and function of Neu differentiation factors
40. Ligand-specific activation of HER-4/p180erbB4, a fourth member of the epidermal growth factor receptor family
41. Molecular cloning and expression of an additional epidermal growth factor receptor-related gene
42. Schwann cell growth factors
43. Neuregulin induces GABA(A) receptor subunit expression and neurite outgrowth in cerebellar granule cells
44. Betacellulin activates the epidermal growth factor receptor and erbB-4, and induces cellular response pattern distinct from those stimulated by epidermal growth factor or neuregulin-β
45. The cellular response to neuregulins is governed by complex interactions of the erbB receptor family
46. Neuregulin and erbB receptors play a critical role in neuronal migration
47. Glial growth factor restricts mammalian neural crest stem cells to a glial fate
48. Epiregulin is a potent pan-ErbB ligand that preferentially activates heterodimeric receptor complexes
49. Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells
50. Signal transduction by receptors with tyrosine kinase activity
51. A role for the acetylcholine receptor-inducing protein ARIA in oligodendrocyte development
52. ErbB-4 activation promotes neurite outgrowth in PC12 cells
53. A reciprocal cell-cell interaction mediated by NT-3 and neuregulins controls the early survival and development of sympathetic neuroblasts
54. Neu Differentiation Factor: A transmembrane glycoprotein containing an EGF domain and an immunoglobulin homology unit
55. Mapping of atypical protein kinase C within the nerve growth factor signaling cascade: Relationship to differentiation and survival of PC12 cells
56. Overexpression of atypical PKC in PC12 cells enhances NGF responsiveness and survival through an NF-kappaB dependent pathway
57. The erbB-related growth factor receptors
58. Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor