Epiregulin is a potent Pan-ErbB ligand that preferentially activates heterodimeric receptor complexes

Journal of Biological Chemistry

Volumn 273, Issue 17, 1998, Pages 10496-10505

  Shelly, Maya ^a   Pinkas Kramarski, Ronit ^a   Guarino, Bradley C ^b   Waterman, Hadassa ^a   Wang, Ling Mei ^c   Lyass, Ljuba ^d   Alimandi, Mauricio ^c   Kuo, Angera ^c   Bacus, Sarah S ^d   Pierce, Jacalyn H ^c   Andrews, Glenn C ^b   Yarden, Yosef ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

^d Advanced Cellular Diagnostics Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR; EPIREGULIN; INTERLEUKIN 3; LIGAND; TYROSINE KINASE RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; CELL DIFFERENTIATION; CELL LINE; CELL PROLIFERATION; LIGAND BINDING; MITOGENESIS; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RECEPTOR DOWN REGULATION;

ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL DIFFERENTIATION; CELL LINE; CHO CELLS; CRICETINAE; DIMERIZATION; DOWN-REGULATION; ENZYME ACTIVATION; EPIDERMAL GROWTH FACTOR; LIGANDS; PHOSPHORYLATION; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; TYROSINE;

EID: 0032562561     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.17.10496     Document Type: Article

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