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Volumn 113, Issue 15-16, 2001, Pages 566-572

Current concepts in pharmacokinetics and their implications for clinical medicine

Author keywords

Clinical pharmacodynamics; Clinical pharmacokinetics; Current concepts; Drug dosing

Indexed keywords

BIOAVAILABILITY; DOSE RESPONSE; DRUG MONITORING; HUMAN; METABOLIC CLEARANCE RATE; PHARMACOKINETICS; REVIEW; TISSUE DISTRIBUTION;

EID: 0035899673     PISSN: 00435325     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (9)

References (71)
  • 2
    • 0006891905 scopus 로고
    • Ueber die bedingungen für die akkumulation indifferenter narkotika (theoretische berechnungen)
    • Widmark E, Tandberg J (1924) Ueber die Bedingungen für die Akkumulation indifferenter Narkotika (theoretische Berechnungen). Biochem Z 147: 358-369
    • (1924) Biochem Z , vol.147 , pp. 358-369
    • Widmark, E.1    Tandberg, J.2
  • 4
    • 0001351283 scopus 로고
    • Studies of urea excretion: II. Relationship between urine volume and the rate of urinary excretion by normal adults
    • Moller E, McIntosh F, VanSlyke D (1929) Studies of urea excretion: II. Relationship between urine volume and the rate of urinary excretion by normal adults. J Clin Invest 6: 427-434
    • (1929) J Clin Invest , vol.6 , pp. 427-434
    • Moller, E.1    McIntosh, F.2    VanSlyke, D.3
  • 5
    • 0033624618 scopus 로고    scopus 로고
    • Evolution of pharmacokinetics and pharmacokinetic/dynamic correlations during the 20th century
    • Hochhaus G, Barrett JS, Derendorf H (2000) Evolution of pharmacokinetics and pharmacokinetic/dynamic correlations during the 20th century. J Clin Pharmacol 40: 908-917
    • (2000) J Clin Pharmacol , vol.40 , pp. 908-917
    • Hochhaus, G.1    Barrett, J.S.2    Derendorf, H.3
  • 7
    • 0033791083 scopus 로고    scopus 로고
    • Botulinumtoxin: Vom gift zum medikament: Ein historischer rückblick
    • Kreyden OP, Geiges ML, Böni R, Burg G (2000) Botulinumtoxin: Vom Gift zum Medikament: Ein historischer Rückblick. Botulinumtoxin: from poison to medicine. A historical review. Der Hautarzt 51: 733-737
    • (2000) Der Hautarzt , vol.51 , pp. 733-737
    • Kreyden, O.P.1    Geiges, M.L.2    Böni, R.3    Burg, G.4
  • 8
    • 0029026230 scopus 로고
    • Approaching a century and after: Morbidity and potentially drug induced disease
    • Fletcher AP (1995) Approaching a century and after: morbidity and potentially drug induced disease. Adverse Drug React Toxicol Rev 14: 45-64
    • (1995) Adverse Drug React Toxicol Rev , vol.14 , pp. 45-64
    • Fletcher, A.P.1
  • 9
    • 0019872135 scopus 로고
    • Medicines then and now
    • Laurence DR (1981) Medicines then and now. Nature 293:13-15
    • (1981) Nature , vol.293 , pp. 13-15
    • Laurence, D.R.1
  • 10
    • 0014212924 scopus 로고
    • Mass drug catastrophes and the roles of science and technology
    • Modell W (1967) Mass drug catastrophes and the roles of science and technology. Science 156: 346-351
    • (1967) Science , vol.156 , pp. 346-351
    • Modell, W.1
  • 11
    • 0025001856 scopus 로고
    • Historical perspectives on anesthetic-related cardiac arrest and resuscitation
    • Somerson SJ (1990) Historical perspectives on anesthetic-related cardiac arrest and resuscitation. AANA J 58: 288-295
    • (1990) AANA J , vol.58 , pp. 288-295
    • Somerson, S.J.1
  • 12
    • 0017283822 scopus 로고
    • Syphilis therapy: An historical perspective
    • Kampmeier RH (1976) Syphilis therapy: an historical perspective. J Am Vener Dis Assoc 3 (2 Pt 2): 99-108
    • (1976) J Am Vener Dis Assoc , vol.3 , Issue.2 PT 2 , pp. 99-108
    • Kampmeier, R.H.1
  • 13
    • 0029031907 scopus 로고
    • Neurosyphilis, or chronic heavy metal poisoning: Karen Blixen's lifelong disease
    • Weismann K (1995) Neurosyphilis, or chronic heavy metal poisoning: Karen Blixen's lifelong disease. Sex Transm Dis 22/3: 137-144
    • (1995) Sex Transm Dis , vol.22 , Issue.3 , pp. 137-144
    • Weismann, K.1
  • 15
    • 0022931406 scopus 로고
    • Historical notes on the therapy of depression
    • Haenel T (1986) Historical notes on the therapy of depression. Schweiz Med Wochenschr 116: 1652-1659
    • (1986) Schweiz Med Wochenschr , vol.116 , pp. 1652-1659
    • Haenel, T.1
  • 16
    • 0029118886 scopus 로고
    • Mozart and medicine in the eighteenth century
    • Jenkins JS (1995) Mozart and medicine in the eighteenth century. J R Soc Med 88/7: 408P-413P
    • (1995) J R Soc Med , vol.88 , Issue.7
    • Jenkins, J.S.1
  • 17
    • 0026236718 scopus 로고
    • The medical history and death of Mozart
    • Jenkins JS (1991) The medical history and death of Mozart. J R Coll Physicians Lond 25/4: 351-353
    • (1991) J R Coll Physicians Lond , vol.25 , Issue.4 , pp. 351-353
    • Jenkins, J.S.1
  • 19
    • 0014191372 scopus 로고
    • Mercury poisoning in Mozart, Beethoven and Schubert?
    • Scheidt W (1967) Mercury poisoning in Mozart, Beethoven and Schubert? Med Klin 62/5: 195-196
    • (1967) Med Klin , vol.62 , Issue.5 , pp. 195-196
    • Scheidt, W.1
  • 20
    • 0020534143 scopus 로고
    • Digitalis poisoning: Historical and forensic aspects
    • Burchell HB (1983) Digitalis poisoning: historical and forensic aspects. J Am Coll Cardiol 1(2 Pt 1): 506-516
    • (1983) J Am Coll Cardiol , vol.1 , Issue.2 PART 1 , pp. 506-516
    • Burchell, H.B.1
  • 21
    • 0031567970 scopus 로고    scopus 로고
    • The pre-flexnerian reports: Mark Twain's criticism of medicine in the United States
    • Ober KP (1997) The Pre-Flexnerian reports: Mark Twain's criticism of medicine in the United States. Ann Intern Med 126: 157-163
    • (1997) Ann Intern Med , vol.126 , pp. 157-163
    • Ober, K.P.1
  • 23
    • 0033663713 scopus 로고    scopus 로고
    • An evolution of drug development and clinical pharmacology during the 20th century
    • Heath G, Colburn WA (2000) An evolution of drug development and clinical pharmacology during the 20th century. J Clin Pharmacol 40/9: 918-929
    • (2000) J Clin Pharmacol , vol.40 , Issue.9 , pp. 918-929
    • Heath, G.1    Colburn, W.A.2
  • 24
    • 0027429687 scopus 로고
    • Therapeutic drug monitoring in cancer management
    • Galpin AJ, Evans WE (1993) Therapeutic drug monitoring in cancer management. Clin Chem 39 (11 Pt 2): 2419-2430
    • (1993) Clin Chem , vol.39 , Issue.11 PART 2 , pp. 2419-2430
    • Galpin, A.J.1    Evans, W.E.2
  • 25
    • 0031955468 scopus 로고    scopus 로고
    • Clinical pharmacokinetics in the 21st century. Does the evidence support definitive outcomes?
    • Ensom MH, Davis GA, Cropp CD, Ensom RJ (1998) Clinical pharmacokinetics in the 21st century. Does the evidence support definitive outcomes? Clin Pharmacokinet 34/4: 265-279
    • (1998) Clin Pharmacokinet , vol.34 , Issue.4 , pp. 265-279
    • Ensom, M.H.1    Davis, G.A.2    Cropp, C.D.3    Ensom, R.J.4
  • 26
    • 0032545976 scopus 로고    scopus 로고
    • Conventional compared with individualized chemotherapy for childhood acute lymphoblastic leukemia
    • Evans WE, Relling MV, Rodman JH, Crom WR, Boyett JM, Pui CH (1998) Conventional compared with individualized chemotherapy for childhood acute lymphoblastic leukemia. N Engl J Med 338/8: 499-505
    • (1998) N Engl J Med , vol.338 , Issue.8 , pp. 499-505
    • Evans, W.E.1    Relling, M.V.2    Rodman, J.H.3    Crom, W.R.4    Boyett, J.M.5    Pui, C.H.6
  • 27
    • 0028831358 scopus 로고
    • The importance of pharmacokinetic/pharmacodynamic surrogate markers to outcome. Focus on antibacterial agents
    • Hyatt JM, McKinnon PS, Zimmer GS, Schentag JJ (1995) The importance of pharmacokinetic/pharmacodynamic surrogate markers to outcome. Focus on antibacterial agents. Clin Pharmacokinet 28/2: 143-160
    • (1995) Clin Pharmacokinet , vol.28 , Issue.2 , pp. 143-160
    • Hyatt, J.M.1    McKinnon, P.S.2    Zimmer, G.S.3    Schentag, J.J.4
  • 28
    • 0029036770 scopus 로고
    • Drug therapy
    • Rochon PA, Gurwitz JH (1995) Drug therapy. Lancet 346 (8966): 32-36
    • (1995) Lancet , vol.346 , Issue.8966 , pp. 32-36
    • Rochon, P.A.1    Gurwitz, J.H.2
  • 29
    • 0032522873 scopus 로고    scopus 로고
    • Incidence of adverse drug reactions in hospitalized patients: A meta-analysis of prospective studies
    • Lazarou J, Pomeranz BH, Corey PN (1998) Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies. JAMA 279/15: 1200-1205
    • (1998) JAMA , vol.279 , Issue.15 , pp. 1200-1205
    • Lazarou, J.1    Pomeranz, B.H.2    Corey, P.N.3
  • 30
    • 0032522594 scopus 로고    scopus 로고
    • Drugs and adverse drug reactions: How worried should we be?
    • Bates DW (1998) Drugs and adverse drug reactions: how worried should we be? JAMA 279/15: 1212
    • (1998) JAMA , vol.279 , Issue.15 , pp. 1212
    • Bates, D.W.1
  • 31
    • 0032542820 scopus 로고    scopus 로고
    • Adverse drug reactions remain a major cause of death
    • Bonn D (1998) Adverse drug reactions remain a major cause of death. Lancet 351 (9110): 1183
    • (1998) Lancet , vol.351 , Issue.9110 , pp. 1183
    • Bonn, D.1
  • 32
    • 0033663712 scopus 로고    scopus 로고
    • Adverse drug rections: A review of relevant factors
    • Ajayi F, Sun H, Perry J (2000) Adverse drug rections: a review of relevant factors. J Clin Pharmacol 40: 1093-1101
    • (2000) J Clin Pharmacol , vol.40 , pp. 1093-1101
    • Ajayi, F.1    Sun, H.2    Perry, J.3
  • 33
    • 0029835506 scopus 로고    scopus 로고
    • Economic evaluations of clinical pharmacy services-1988-1995
    • The Publications Committee of the American College of Clinical Pharmacy
    • Schumock GT, Meek PD, Ploetz PA, Vermeulen LCPo AL, Zhang WY (1996) Economic evaluations of clinical pharmacy services-1988-1995. The Publications Committee of the American College of Clinical Pharmacy. Pharmacotherapy 16/6: 1188-1208
    • (1996) Pharmacotherapy , vol.16 , Issue.6 , pp. 1188-1208
    • Schumock, G.T.1    Meek, P.D.2    Ploetz, P.A.3    Vermeulen, L.C.4    Po, A.L.5    Zhang, W.Y.6
  • 34
    • 0032753835 scopus 로고    scopus 로고
    • Clinical pharmacy saves money and lives-so what's new?
    • Angaran DM (1999) Clinical pharmacy saves money and lives-so what's new? Pharmacotherapy 19/12: 1352-1353
    • (1999) Pharmacotherapy , vol.19 , Issue.12 , pp. 1352-1353
    • Angaran, D.M.1
  • 35
    • 0019922166 scopus 로고
    • Documented effectiveness of clinical pharmacy services
    • Gibson FM, Hyneck ML, Scherrer JJ (1982) Documented effectiveness of clinical pharmacy services. Am J Hosp Pharm 39/11: 1902-1903
    • (1982) Am J Hosp Pharm , vol.39 , Issue.11 , pp. 1902-1903
    • Gibson, F.M.1    Hyneck, M.L.2    Scherrer, J.J.3
  • 36
    • 0039852179 scopus 로고    scopus 로고
    • Clinical pharmacokinetics during drug development
    • Eldon MA (1996) Clinical pharmacokinetics during drug development. Appl Clin Trials 5: 56-64
    • (1996) Appl Clin Trials , vol.5 , pp. 56-64
    • Eldon, M.A.1
  • 37
    • 0002907225 scopus 로고    scopus 로고
    • Tissue distribution measurements during clinical drug development
    • Müller M, Eichler HG (1999) Tissue distribution measurements during clinical drug development. Appl Clin Trials 8: 56-60
    • (1999) Appl Clin Trials , vol.8 , pp. 56-60
    • Müller, M.1    Eichler, H.G.2
  • 38
    • 0032551211 scopus 로고    scopus 로고
    • What lessons can be learnt from withdrawal of mibefradil from the market?
    • Po AL, Zhang WY (1998) What lessons can be learnt from withdrawal of mibefradil from the market? Lancet 351: 1829-1830
    • (1998) Lancet , vol.351 , pp. 1829-1830
    • Po, A.L.1    Zhang, W.Y.2
  • 39
    • 0002008964 scopus 로고
    • Clinical pharmacokinetics: The use of plasma concentrations of drugs
    • Melmon KL, Morelli HF (eds) Macmillan, New York
    • Sheiner LB, Tozer TN (1978) Clinical pharmacokinetics: the use of plasma concentrations of drugs. In: Melmon KL, Morelli HF (eds) Clinical pharmacology: basic principles of therapeutics. Macmillan, New York, pp 71-109
    • (1978) Clinical Pharmacology: Basic Principles of Therapeutics , pp. 71-109
    • Sheiner, L.B.1    Tozer, T.N.2
  • 40
    • 0023219734 scopus 로고
    • Transport of molecules in the tumor interstitium: A review
    • Jain RK (1987) Transport of molecules in the tumor interstitium: a review. Cancer Res 47: 3039-3051
    • (1987) Cancer Res , vol.47 , pp. 3039-3051
    • Jain, R.K.1
  • 41
    • 0031747280 scopus 로고    scopus 로고
    • The next frontier of molecular medicine: Delivery of therapeutics
    • Jain RK (1998) The next frontier of molecular medicine: delivery of therapeutics. Nat Med 4: 655-657
    • (1998) Nat Med , vol.4 , pp. 655-657
    • Jain, R.K.1
  • 42
    • 0034672531 scopus 로고    scopus 로고
    • Microdialysis in clinical drug delivery studies
    • Müller M (2000) Microdialysis in clinical drug delivery studies. Adv Drug Deliv Rev 45/2-3: 255-269
    • (2000) Adv Drug Deliv Rev , vol.45 , Issue.2-3 , pp. 255-269
    • Müller, M.1
  • 43
    • 0034913471 scopus 로고    scopus 로고
    • Microdialysis - A novel tool for clinical studies of ani-infectives
    • in press
    • Joukhadar C, Derendorf H, Müller M (2001) Microdialysis - a novel tool for clinical studies of ani-infectives. Eur J Clin Pharmacol (in press)
    • (2001) Eur J Clin Pharmacol
    • Joukhadar, C.1    Derendorf, H.2    Müller, M.3
  • 45
    • 0030819215 scopus 로고    scopus 로고
    • Basic concepts of pharmacokinetic/pharmacodynamic (PK/PD) modelling
    • Meibohm B, Derendorf H (1997) Basic concepts of pharmacokinetic/pharmacodynamic (PK/PD) modelling. Int J Clin Pharmacol Ther 35: 401-413
    • (1997) Int J Clin Pharmacol Ther , vol.35 , pp. 401-413
    • Meibohm, B.1    Derendorf, H.2
  • 46
    • 0030782631 scopus 로고    scopus 로고
    • Pharmacokinetic-pharmacodynamic modelling of the in vitro anti-infective effect of piperacillin-tazobactam combinations
    • Dalla Costa T, Nolting A, Rand K, Derendorf H (1997) Pharmacokinetic-pharmacodynamic modelling of the in vitro anti-infective effect of piperacillin-tazobactam combinations. Int J Clin Pharmacol Ther 35: 426-433
    • (1997) Int J Clin Pharmacol Ther , vol.35 , pp. 426-433
    • Dalla Costa, T.1    Nolting, A.2    Rand, K.3    Derendorf, H.4
  • 47
    • 0023145387 scopus 로고
    • Rate of increase in the plasma concentration of nifedipine as a major determinant of its hemodynamic effects in humans
    • Kleinbloesem CH, van Brummelen P, Danhof M, Faber H, Urquhart J, Breimer DD (1987) Rate of increase in the plasma concentration of nifedipine as a major determinant of its hemodynamic effects in humans. Clin Pharmacol Ther 41/1: 26-30
    • (1987) Clin Pharmacol Ther , vol.41 , Issue.1 , pp. 26-30
    • Kleinbloesem, C.H.1    Van Brummelen, P.2    Danhof, M.3    Faber, H.4    Urquhart, J.5    Breimer, D.D.6
  • 48
    • 0024539308 scopus 로고
    • Prospective randomized comparison of continuous infusion fluorouracil with a conventional bolus schedule in metastatic colorectal carcinoma: A Mid-Atlantic Oncology Program Study
    • Lokich JJ, Ahlgren JD, Gullo JJ, Philips JA, Fryer JG A (1989) prospective randomized comparison of continuous infusion fluorouracil with a conventional bolus schedule in metastatic colorectal carcinoma: a Mid-Atlantic Oncology Program Study. J Clin Oncol 7/4: 425-432
    • (1989) J Clin Oncol , vol.7 , Issue.4 , pp. 425-432
    • Lokich, J.J.1    Ahlgren, J.D.2    Gullo, J.J.3    Philips, J.A.4    Fryer, J.G.5
  • 49
    • 0031788714 scopus 로고    scopus 로고
    • The application of population pharmacokinetics to the drug development process
    • Jackson KA, Rosenbaum SE (1998) The application of population pharmacokinetics to the drug development process. Drug Dev Ind Pharm 24: 1155-1162
    • (1998) Drug Dev Ind Pharm , vol.24 , pp. 1155-1162
    • Jackson, K.A.1    Rosenbaum, S.E.2
  • 51
    • 0029821530 scopus 로고    scopus 로고
    • The Gulf War, stress and a leaky blood-brain barrier
    • Hanin I (1996) The Gulf War, stress and a leaky blood-brain barrier. Nat Med 2/12: 1307-1308
    • (1996) Nat Med , vol.2 , Issue.12 , pp. 1307-1308
    • Hanin, I.1
  • 52
    • 0028231298 scopus 로고
    • Association of intratumoral pharmacokinetics of fluorouracil with clinical response
    • Presant CA, Wolf W, Waluch V, Wiseman C, Kennedy P, Blayney D, Brechner RR (1994) Association of intratumoral pharmacokinetics of fluorouracil with clinical response. Lancet 343 (8907): 184-187
    • (1994) Lancet , vol.343 , Issue.8907 , pp. 184-187
    • Presant, C.A.1    Wolf, W.2    Waluch, V.3    Wiseman, C.4    Kennedy, P.5    Blayney, D.6    Brechner, R.R.7
  • 56
    • 0031409699 scopus 로고    scopus 로고
    • The role of positron emission tomography in pharmacokinetic analysis
    • Fischman AJ, Alpert NM, Babich JW, Rubin RH (1997) The role of positron emission tomography in pharmacokinetic analysis. Drug Metab Rev 29: 923-956
    • (1997) Drug Metab Rev , vol.29 , pp. 923-956
    • Fischman, A.J.1    Alpert, N.M.2    Babich, J.W.3    Rubin, R.H.4
  • 57
    • 0031933749 scopus 로고    scopus 로고
    • Drug distribution - The forgotten relative of clinical pharmacokinetics
    • Eichler HG, Müller M (1998) Drug distribution - the forgotten relative of clinical pharmacokinetics. Clin Pharmacokinet 34: 95-99
    • (1998) Clin Pharmacokinet , vol.34 , pp. 95-99
    • Eichler, H.G.1    Müller, M.2
  • 58
    • 0030942858 scopus 로고    scopus 로고
    • Application of microdialysis in pharmacokinetic studies
    • Elmquist WF, Sawchuk RJ (1997) Application of microdialysis in pharmacokinetic studies. Pharm Res 14: 267-288
    • (1997) Pharm Res , vol.14 , pp. 267-288
    • Elmquist, W.F.1    Sawchuk, R.J.2
  • 59
    • 70449136457 scopus 로고
    • Drug reactions, enzymes and biochemical genetics
    • Motulsky AG (1957) Drug reactions, enzymes and biochemical genetics. JAMA 165: 835-836
    • (1957) JAMA , vol.165 , pp. 835-836
    • Motulsky, A.G.1
  • 60
    • 0014403645 scopus 로고
    • Genetic control of drug levels in man: Antipyrine
    • Vesell ES, Page JG (1968) Genetic control of drug levels in man: antipyrine. Science 161 (836): 72-73
    • (1968) Science , vol.161 , Issue.836 , pp. 72-73
    • Vesell, E.S.1    Page, J.G.2
  • 61
    • 0014433956 scopus 로고
    • Genetic control of drug levels in man: Phenylbutazone
    • Vesell ES, Page JG (1968) Genetic control of drug levels in man: phenylbutazone. Science 159 (822): 1479-1480
    • (1968) Science , vol.159 , Issue.822 , pp. 1479-1480
    • Vesell, E.S.1    Page, J.G.2
  • 62
    • 0033668881 scopus 로고    scopus 로고
    • Advances in pharmacogenetics and pharmacogenomics
    • Vesell ES (2000) Advances in pharmacogenetics and pharmacogenomics. J Clin Pharmacol 40/9: 930-938
    • (2000) J Clin Pharmacol , vol.40 , Issue.9 , pp. 930-938
    • Vesell, E.S.1
  • 63
    • 0000616920 scopus 로고
    • Enzymatic deficiency in primaquine-sensitive erythrocytes
    • Carsen PE, Flanagan CL, Iokes CE, Alving AS (1956) Enzymatic deficiency in primaquine-sensitive erythrocytes. Science 124: 484-485
    • (1956) Science , vol.124 , pp. 484-485
    • Carsen, P.E.1    Flanagan, C.L.2    Iokes, C.E.3    Alving, A.S.4
  • 65
    • 33947223647 scopus 로고    scopus 로고
    • Pharmacogenomics: The promise of personalized medicine
    • article 4
    • Mancinelli L, Cronin M, Sadee W (2000) Pharmacogenomics: The Promise of Personalized Medicine. (http://www.pharmsci.org/ScientificJournals/pharmsci/ journal/4.html) AAPS Pharmsci 2(1) article 4
    • (2000) AAPS Pharmsci , vol.2 , Issue.1
    • Mancinelli, L.1    Cronin, M.2    Sadee, W.3
  • 67
    • 0035798916 scopus 로고    scopus 로고
    • Efficacy of inhaled human insulin in type 1 diabetes mellitus: A randomised proof-of-concept study
    • Skyler JS, Cefalu WT, Kourides IA, Landschulz WH, Balagtas CC, Cheng SL, Gelfand RA for The Inhaled Insulin Phase II Study Group (2001) Efficacy of inhaled human insulin in type 1 diabetes mellitus: a randomised proof-of-concept study. Lancet 357: 9253: 331
    • (2001) Lancet , vol.357 , Issue.9253 , pp. 331
    • Skyler, J.S.1    Cefalu, W.T.2    Kourides, I.A.3    Landschulz, W.H.4    Balagtas, C.C.5    Cheng, S.L.6    Gelfand, R.A.7
  • 68
    • 0033611506 scopus 로고    scopus 로고
    • A controlled-release microchip
    • Santini JT, Cima MJ, Langer R (1999) A controlled-release microchip. Nature 397/6717: 335-338
    • (1999) Nature , vol.397 , Issue.6717 , pp. 335-338
    • Santini, J.T.1    Cima, M.J.2    Langer, R.3
  • 69
    • 0035235171 scopus 로고    scopus 로고
    • Targeted systemic chemotherapy using magnetic liposomes with incorporated adriamycin for osteosarcoma in hamsters
    • Kubo T, Sugita T, Shimose S, Nitta Y, Ikuta Y, Murakami T (2001) Targeted systemic chemotherapy using magnetic liposomes with incorporated adriamycin for osteosarcoma in hamsters. Int J Oncol 18/1: 121-125
    • (2001) Int J Oncol , vol.18 , Issue.1 , pp. 121-125
    • Kubo, T.1    Sugita, T.2    Shimose, S.3    Nitta, Y.4    Ikuta, Y.5    Murakami, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.