메뉴 건너뛰기




Volumn 2, Issue 1, 2000, Pages 29-41

Pharmacogenomics: The promise of personalized medicine

Author keywords

Pharmacogenomics

Indexed keywords

CYTOCHROME P 450 ENZYME SYSTEM; CYTOCHROME P450; DRUG;

EID: 33947223647     PISSN: 15221059     EISSN: None     Source Type: Journal    
DOI: 10.1208/ps020104     Document Type: Article
Times cited : (184)

References (39)
  • 1
    • 0032522873 scopus 로고    scopus 로고
    • Incidence of adverse drug reactions in hospitalized patients
    • Lazarou J, Pomeranz BH, Corey PN. Incidence of adverse drug reactions in hospitalized patients. JAMA. 1998;279:1200-1205.
    • (1998) JAMA , vol.279 , pp. 1200-1205
    • Lazarou, J.1    Pomeranz, B.H.2    Corey, P.N.3
  • 2
    • 0031823433 scopus 로고    scopus 로고
    • Finding the right drug for the right patient
    • Sadee W. Finding the right drug for the right patient. Pharm Res. 1998;15:959-963.
    • (1998) Pharm Res , vol.15 , pp. 959-963
    • Sadee, W.1
  • 4
    • 50749093820 scopus 로고
    • The incidence of alcaptonuria: A study in chemical individuality
    • Garrod AE. The incidence of alcaptonuria: a study in chemical individuality. Lancet. 1902;ii:1616-1620.
    • (1902) Lancet , vol.2 , pp. 1616-1620
    • Garrod, A.E.1
  • 5
    • 0001470653 scopus 로고
    • Studies in human inheritance
    • Snyder LH. Studies in human inheritance. Ohio J Sci. 1932;32:436-468.
    • (1932) Ohio J Sci , vol.32 , pp. 436-468
    • Snyder, L.H.1
  • 7
    • 0030666917 scopus 로고    scopus 로고
    • Pharmacogenetics: 65 candles on the cake
    • Nebert DW. Pharmacogenetics: 65 candles on the cake. Pharmacogenetics. 1997;7:435-440.
    • (1997) Pharmacogenetics , vol.7 , pp. 435-440
    • Nebert, D.W.1
  • 9
    • 0000616920 scopus 로고
    • Enzymatic deficiency in primaquine-sensitive erythrocytes
    • Carsen PE, Flanagan CL, lokes CE, Alving AS. Enzymatic deficiency in primaquine-sensitive erythrocytes. Science. 1956;124,484-485.
    • (1956) Science , vol.124 , pp. 484-485
    • Carsen, P.E.1    Flanagan, C.L.2    Lokes, C.E.3    Alving, A.S.4
  • 10
    • 0006948626 scopus 로고
    • Metabolism of isoniazid in man as related to the occurrence of peripheral neuritis
    • Hughes HB, Biehl JP, Jones AP, Schmidt, LH. Metabolism of isoniazid in man as related to the occurrence of peripheral neuritis. Am Rev Tuberculosis. 1954;70:266-273.
    • (1954) Am Rev Tuberculosis , vol.70 , pp. 266-273
    • Hughes, H.B.1    Biehl, J.P.2    Jones, A.P.3    Schmidt, L.H.4
  • 11
    • 26444539817 scopus 로고
    • Genetic control of isoniazid metabolism in man
    • Evans DAP, Manley KA, McKusick VA. Genetic control of isoniazid metabolism in man. Br Med J. 1960;2:485-490.
    • (1960) Br Med J , vol.2 , pp. 485-490
    • Evans, D.A.P.1    Manley, K.A.2    McKusick, V.A.3
  • 13
    • 70449136457 scopus 로고
    • Drug reactions, enzymes and biochemical genetics
    • Motulsky AG. Drug reactions, enzymes and biochemical genetics. JAMA. 1957;165:835-837.
    • (1957) JAMA , vol.165 , pp. 835-837
    • Motulsky, A.G.1
  • 14
    • 0018615011 scopus 로고
    • Defective N-oxidation of sparteine in man: A new pharmacogenetic defect
    • Eichelbaum M, Steincke B, Dengler JJ. Defective N-oxidation of sparteine in man: a new pharmacogenetic defect. Eur J Clin Pharmacol. 1977;16:183-187.
    • (1977) Eur J Clin Pharmacol , vol.16 , pp. 183-187
    • Eichelbaum, M.1    Steincke, B.2    Dengler, J.J.3
  • 15
    • 0018822866 scopus 로고
    • Mercaptopurine pharmacogenetics: Monogenic inheritance of erythrocyte thiopurine methyltransferase activity
    • Weinshilboum RM, Sladek SL. Mercaptopurine pharmacogenetics: monogenic inheritance of erythrocyte thiopurine methyltransferase activity. Am J Hum Genet. 1980;32:651-62.
    • (1980) Am J Hum Genet , vol.32 , pp. 651-662
    • Weinshilboum, R.M.1    Sladek, S.L.2
  • 16
    • 0029919807 scopus 로고    scopus 로고
    • Thiopurine S-methyltransferase deficiency: Two nucleotide transitions define the most prevalent mutant allele associated with loss of catalytic activity in Caucasians
    • Tai H, Krynetski EY, Yates CR, et al. Thiopurine S-methyltransferase deficiency: two nucleotide transitions define the most prevalent mutant allele associated with loss of catalytic activity in Caucasians. Am J Hum Genet. 1996;58:694-702.
    • (1996) Am J Hum Genet , vol.58 , pp. 694-702
    • Tai, H.1    Krynetski, E.Y.2    Yates, C.R.3
  • 17
    • 0032895235 scopus 로고    scopus 로고
    • Trastuzumab, a recombinant DNA derived humanized monoclonal antibody, a novel agent for the treatment of metastatic breast cancer
    • Goldenberg MM. Trastuzumab, a recombinant DNA derived humanized monoclonal antibody, a novel agent for the treatment of metastatic breast cancer. Clin Therapeut. 1999;21:309-318.
    • (1999) Clin Therapeut , vol.21 , pp. 309-318
    • Goldenberg, M.M.1
  • 18
    • 0032127350 scopus 로고    scopus 로고
    • Recombinant humanized anti-HER2 antibody (HERCEPTIN) enhances the antitumor activity of paclitaxel and doxorubicin against HER2/neu overexpressing human breast cancer xenografts
    • Baselge J, Norton L, Albanell J, Kim YM, Mendelsohn J. Recombinant humanized anti-HER2 antibody (HERCEPTIN) enhances the antitumor activity of paclitaxel and doxorubicin against HER2/neu overexpressing human breast cancer xenografts. Cancer Res. 1998;58:2825-2831.
    • (1998) Cancer Res , vol.58 , pp. 2825-2831
    • Baselge, J.1    Norton, L.2    Albanell, J.3    Kim, Y.M.4    Mendelsohn, J.5
  • 19
    • 0031438775 scopus 로고    scopus 로고
    • Clinical implications of genetic polymorphisms and drug interactions mediated by cytochrome P450 enzymes
    • Touw DJ. Clinical implications of genetic polymorphisms and drug interactions mediated by cytochrome P450 enzymes. Drug Metab Drug Interact. 1997;14:55-82.
    • (1997) Drug Metab Drug Interact , vol.14 , pp. 55-82
    • Touw, D.J.1
  • 20
    • 0003458803 scopus 로고
    • Genetic factors in drug therapy
    • Cambridge: Cambridge University Press
    • Evans DAP. Genetic factors in drug therapy. In: Clinical and Molecular Pharmacogenetics. Cambridge: Cambridge University Press; 1993.
    • (1993) Clinical and Molecular Pharmacogenetics
    • Evans, D.A.P.1
  • 21
    • 0026817161 scopus 로고
    • Clinical implications of variable antiarrythmic drug metabolism
    • Buchert E, Woosley RL. Clinical implications of variable antiarrythmic drug metabolism. Pharmacogenet. 1992;2:2-11.
    • (1992) Pharmacogenet , vol.2 , pp. 2-11
    • Buchert, E.1    Woosley, R.L.2
  • 22
    • 0027483214 scopus 로고
    • Genetically variable metabolism of antidepressants and neuroleptic drugs in man
    • Dahl AK, Bertilsson, L. Genetically variable metabolism of antidepressants and neuroleptic drugs in man. Pharmacogenet. 1993;3:61-70.
    • (1993) Pharmacogenet , vol.3 , pp. 61-70
    • Dahl, A.K.1    Bertilsson, L.2
  • 23
    • 0032905234 scopus 로고    scopus 로고
    • Clinically significant pharmacokinetic drug interactions with psychoactive drugs: Antidepressants and antipsychotics and the cytochrome P450 system
    • Tanaka E, Hisawa S. Clinically significant pharmacokinetic drug interactions with psychoactive drugs: antidepressants and antipsychotics and the cytochrome P450 system. J Clin Pharm Ther. 1999;24:7-16
    • (1999) J Clin Pharm Ther , vol.24 , pp. 7-16
    • Tanaka, E.1    Hisawa, S.2
  • 25
    • 0028856846 scopus 로고
    • Molecular basis of polymorphic drug metabolism
    • Daly AK. Molecular basis of polymorphic drug metabolism. J Mol Med. 1995;73:39-553.
    • (1995) J Mol Med , vol.73 , pp. 39-553
    • Daly, A.K.1
  • 26
    • 0027983085 scopus 로고
    • Pharmacogenetic phenytyping and genotyping. Present status and future potential
    • Gonzales FJ. Pharmacogenetic phenytyping and genotyping. Present status and future potential. Clin Pharmacokinet. 1994;26:59-70.
    • (1994) Clin Pharmacokinet , vol.26 , pp. 59-70
    • Gonzales, F.J.1
  • 27
    • 0028929553 scopus 로고
    • The application of in vitro models of drug metabolism and toxicity in drug discovery and drug development
    • Ball SE, Scatina JA, Sisenwine SF, Fisher GL. The application of in vitro models of drug metabolism and toxicity in drug discovery and drug development. Drug Chem Toxicity. 1995;18:1-28.
    • (1995) Drug Chem Toxicity , vol.18 , pp. 1-28
    • Ball, S.E.1    Scatina, J.A.2    Sisenwine, S.F.3    Fisher, G.L.4
  • 28
    • 0031726283 scopus 로고    scopus 로고
    • The Environmental Genome Project: Functional analysis of polymorphisms
    • Guengerich F. The Environmental Genome Project: Functional analysis of polymorphisms. Environment Health Perspect. 1998;106:365-368.
    • (1998) Environment Health Perspect , vol.106 , pp. 365-368
    • Guengerich, F.1
  • 29
    • 0032544336 scopus 로고    scopus 로고
    • Genetic variation as a guide to drug development
    • Kleyn PW, Vesell ES. Genetic variation as a guide to drug development. Science. 1998;281:1820-1821.
    • (1998) Science , vol.281 , pp. 1820-1821
    • Kleyn, P.W.1    Vesell, E.S.2
  • 30
    • 0033552467 scopus 로고    scopus 로고
    • Pharmacogenomics
    • Sadee W. Pharmacogenomics. BMJ. 1999;319:1286.
    • (1999) BMJ , vol.319 , pp. 1286
    • Sadee, W.1
  • 31
    • 0033569516 scopus 로고    scopus 로고
    • Pharmacogenomics: Translating functional genomics into rational therapeutics
    • Evans WE, Relling MV. Pharmacogenomics: translating functional genomics into rational therapeutics. Science. 1999;286:487-491.
    • (1999) Science , vol.286 , pp. 487-491
    • Evans, W.E.1    Relling, M.V.2
  • 32
    • 0032903908 scopus 로고    scopus 로고
    • The transcriptional program in the response of human fibroblasts to serum
    • Iyer VR, Eisen MB, Ross DT, et al. The transcriptional program in the response of human fibroblasts to serum. Science. 1999;283,83-87.
    • (1999) Science , vol.283 , pp. 83-87
    • Iyer, V.R.1    Eisen, M.B.2    Ross, D.T.3
  • 34
    • 0001271546 scopus 로고    scopus 로고
    • Integrated capillary electrophoresis devices with an efficient postcolumn reactor in planar quartz and glass chips
    • Fluri KG, Fitzpatrick G, Chiem N, Harrison DJ. Integrated capillary electrophoresis devices with an efficient postcolumn reactor in planar quartz and glass chips. Anal Chem. 1996;68:4285-4290.
    • (1996) Anal Chem , vol.68 , pp. 4285-4290
    • Fluri, K.G.1    Fitzpatrick, G.2    Chiem, N.3    Harrison, D.J.4
  • 35
    • 2842550379 scopus 로고    scopus 로고
    • Integrated microdevice for DNA restriction fragment analysis
    • Jacobson SC, Ramsey SC. Integrated microdevice for DNA restriction fragment analysis. Anal Chem. 1996;68:720-723.
    • (1996) Anal Chem , vol.68 , pp. 720-723
    • Jacobson, S.C.1    Ramsey, S.C.2
  • 36
    • 0032829373 scopus 로고    scopus 로고
    • Cheap DNA arrays-;it's not all smoke and mirrors
    • Blanchard AP, Friend SH. Cheap DNA arrays-;it's not all smoke and mirrors. Nature Biotech. 1999;17:953.
    • (1999) Nature Biotech , vol.17 , pp. 953
    • Blanchard, A.P.1    Friend, S.H.2
  • 37
    • 0002944984 scopus 로고    scopus 로고
    • Big pharma hedges its bets
    • Russo E. Big pharma hedges its bets. The Scientist. 1999;13:1.
    • (1999) The Scientist , vol.13 , pp. 1
    • Russo, E.1
  • 39
    • 0004120124 scopus 로고    scopus 로고
    • New York: Oxford University Press
    • Weber WW. Pharmacogenetics. New York: Oxford University Press; 1997.
    • (1997) Pharmacogenetics
    • Weber, W.W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.