Prodigiosin-induced apoptosis in human colon cancer cells

Life Sciences

Volumn 68, Issue 17, 2001, Pages 2025-2036

  Montaner, Beatriz ^a   Pérez Tomás, Ricardo ^a,b  

^a UNIVERSITY OF BARCELONA   (Spain)

^b Pavelló Central 5a Planta LR 51 C ^*  (Spain)

Author keywords

Apoptosis; Cancer cell lines; Chemotherapy; Colon; Prodigiosin

Indexed keywords

DNA FRAGMENT; PRODIGIOSIN;

ANALYTIC METHOD; ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER CHEMOTHERAPY; CELL STRAIN; CELL STRUCTURE; CELL VIABILITY; COLON CARCINOMA; CONTROLLED STUDY; DRUG EFFECT; DRUG PURIFICATION; DRUG STRUCTURE; HUMAN; HUMAN CELL; IC 50; MOUSE; NONHUMAN; RAT;

3T3 CELLS; ADENOCARCINOMA; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; BENZIMIDAZOLES; CASPASES; CELL SURVIVAL; COLONIC NEOPLASMS; DNA; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME ACTIVATION; FLUORESCENT DYES; HUMANS; MICE; PRODIGIOSIN; SERRATIA MARCESCENS; TETRAZOLIUM SALTS; THIAZOLES; TUMOR CELLS, CULTURED;

SERRATIA MARCESCENS;

EID: 0035896188     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(01)01002-5     Document Type: Article

References (37)

1. Chemoprevention of colorectal cancer
2. Lovastatin augments sulindac-induced apoptosis in colon cancer cells and potentiates chemopreventive effects of sulindac
3. Aspirin induces cell death and caspase-dependent phosphatidylserine externalization in HT-29 human colon adenocarcinoma cells
4. Role of adjuvant therapy in surgically resected colorectal carcinoma
5. Novel chemotherapeutic agents for gastrointestinal cancers
6. The medical treatment of colorectal cancer: Actual status and new developments
7. Therapy for early-stage colorectal cancer
8. Apoptosis and the dilemma of cancer chemotherapy
9. Disruption of p53 in human cancer cells alters the responses to therapeutic agents
10. Social controls on cell survival and cell death
11. An evolutionary perspective on apoptosis
12. Apoptosis. Its significance in cancer and cancer therapy
13. Perspectives series: Host/pathogen interactions. Apoptosis in bacterial pathogenesis
14. Macrophage killing is an essential virulence mechanism of Salmonella typhimurium
15. Salmonella spp. are cytotoxic for cultured macrophages
16. Salmonella typhimurium invasion induces apoptosis in infected macrophages
17. Characterization of a streptococcal antitumor glycoprotein (SAGP)
18. Characterization of the new immunosuppressive drug undecylprodigiosin in human lymphocytes
19. - symporter, induces apoptosis in human and rat hepatocellular cancer cell lines in vitro and inhibits the growth of hepatocellular carcinoma xenografts in nude mice
20. Induction of apoptosis of activated murine spleenic T cells by cycloprodigiosin hydrochloride, a novel immunosuppressant
21. Total synthesis of prodigiosin, prodigiosene, and desmethoxyprodigiosin: Diels-Alder reactions of heterocyclic azadienes and development of an effective palladium (II)-promoted 2,2′-bipyrrole coupling procedure
22. Prodigiosin formation by Serratia marcescens in a chemostat
23. Isolation and characterization of Serratia marcescens mutants defective in prodigiosin biosynthesis
24. Thiamine-induced formation of the monopyrrole moiety of prodigiosin
25. Prodigiosin from the supernatant of Serratia marcescens induces apoptosis in hematopoietic cancer cell lines
26. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
27. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
28. Involvement of CED-3/ICE proteases in the apoptosis of B-chronic lymphocytic leukemia cells
29. - symporters that uncouple proton translocators
30. Prodigiosins uncouple lysosomal vacuolar-type ATPase through promotion of H+/Cl- symport
31. New immunosuppressive drug PNU156804 blocks IL-2-dependent proliferation and NF-kappa B and AP-1 activation
32. Association of p53 mutations with short survival in colorectal cancer
33. p53 nuclear overexpression: An independent predictor of survival in lymph node - Positive colorectal cancer patients
34. Apoptosis, p53, and tumor cell sensitivity to anticancer agents
35. Beta-lapachone induces cell cycle arrest and apoptosis in human colon cancer cells
36. Evidence of reciprocity of bcl-2 and p53 expression in human colorectal adenomas and carcinomas
37. BCL-2 expression in human colorectal adenomas and carcinomas