Depletion of systemic macrophages by liposome-encapsulated clodronate attenuates striatal macrophage invasion and neurodegeneration following local endotoxin infusion in gerbils

Brain Research

Volumn 892, Issue 1, 2001, Pages 13-26

  Zito, Mark A ^a   Koennecke, Lutz A ^a   McAuliffe, Matthew J ^a   McNally, Bevin ^a   Van Rooijen, Nico ^b   Heyes, Melvyn P ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

Animal model; Inflammation; Macrophage; Migroglia; Neurodegeneration

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CLODRONIC ACID; LIPOSOME;

ANIMAL EXPERIMENT; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CORPUS STRIATUM; GERBIL; INFLAMMATION; MACROPHAGE MIGRATION; MACROPHAGE MIGRATION INHIBITION; MICROGLIA; MONOCYTE; MOUSE; NERVE DEGENERATION; NEUROLOGIC DISEASE; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; STAINING;

ANALYSIS OF VARIANCE; ANIMALS; CLODRONIC ACID; CORPUS STRIATUM; DRUG CARRIERS; ENDOTOXINS; GERBILLINAE; INFUSIONS, PARENTERAL; LEUKOCYTES; LIPOPOLYSACCHARIDES; LIPOSOMES; MACROPHAGES; MICE; MICE, INBRED C57BL; NERVE DEGENERATION; SALMONELLA;

EID: 0035895842     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(00)03135-8     Document Type: Article

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