Allele-specific non-CpG methylation of the Nf1 gene during early mouse development

Developmental Biology

Volumn 240, Issue 2, 2001, Pages 585-598

  Haines, Thomas R ^a   Rodenhiser, David I ^a   Ainsworth, Peter J ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Allele specific; Development; Methylation; Mouse; Neurofibromatosis; Non CpG

Indexed keywords

BISULFITE; CYTOSINE; DINUCLEOTIDE; GENE PRODUCT; NEUROFIBROMIN; PROTEIN NF1; UNCLASSIFIED DRUG;

ALLELE; ALLELISM; ANIMAL TISSUE; ARTICLE; CPG ISLAND; EMBRYO DEVELOPMENT; GENE LOCATION; GENE SEQUENCE; METHYLATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OOCYTE; OVULATION; PRIORITY JOURNAL; SPERM;

DROSOPHILA; MURINAE;

EID: 0035894537     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1006/dbio.2001.0504     Document Type: Article

References (47)

1. Differential H4 acetylation of paternal and maternal chromatin precedes DNA replication and differential transcriptional activity in pronuclei of 1-cell mouse embryos
2. Identification and characterization of sporadic and inherited mutations in exon 31 of the neurofibromatosis (NF1) gene
3. Example of somatic mosaicism in a series of de novo neurofibromatosis type 1 cases due to a maternally derived deletion
4. Site and sequence specific DNA methylation in the neurofibromatosis (NFL) gene includes C5839T: The site of the recurrent substitution mutation in exon 31
5. Regulation of transcriptional activity during the first and second cell cycles in the preimplantation mouse embryo
6. DNA and total protamine masses in individual sperm from fertile mammalian subjects
7. Endogenous transcription occurs at the 1-cell stage in the mouse embryo
8. The ontogeny of allele-specific methylation associated with imprinted genes in the mouse
9. High sensitivity mapping of methylated cytosines
10. The characteristics of DNA methylation in an in vitro DNA synthesizing system from mouse fibroblasts
11. Methylation levels of maternal and paternal genomes during preimplantation development
12. Drosophila proteins related to vertebrate DNA (5-cytosine) methyltransferases
13. Paternal origin of new mutations in von Recklinghausen neurofibromatosis
14. Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
15. Mechanism of DNA demethylation in vertebrates and its biological significance
16. Developmental pattern of gene-specific DNA methylation in the mouse embryo and germ line
17. Mechanistic aspects of genome-wide demethylation in the preimplantation mouse embryo
18. DNA methylation and cancer
19. Sex differences in mutational rate and mutational mechanism in the NF1 gene in neurofibromatosis type 1 patients
20. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
21. DNA methylation in Drosophila melanogaster
22. Demethylation of the zygotic paternal genome
23. Bisulfite genomic sequencing-derived methylation profile of the xist gene throughout early mouse development
24. Temporal and regional changes in DNA methylation in the embryonic, extraembryonic and germ cell lineages during mouse embryo development
25. Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
26. DNA methyltransferase Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
27. Variable effects of DNA-synthesis inhibitors upon DNA methylation in mammalian cells
28. A modified improved method for bisulfite based cytosine methylation analysis
29. Active demethylation of the paternal genome in the mouse zygote
30. Reporter gene expression in G2 of the 1-cell mouse embryo
31. Non-CpG methylation is prevalent in embryonic stem cells and be mediated by DNA methyltransferase 3a
32. DNA methylation and gene function
33. DNA methylation from embryo to adult
34. Homonucleotide tracts, short repeats and CpG/CpNpG motifs are frequent sites for heterogeneous mutations in the neurofibromatosis type 1 (NF1) tumour-suppressor gene
35. Methylation of mouse DNA in vivo: di- and tripyrimidime sequences containing 5-methylcytosine
36. DNA methylation
37. Preferential mutation of the neurofibromatosis type 1 gene in paternally derived chromosomes
38. Imprinting and the initiation of gene silencing in the germ line
39. The methyl-CpG-binding protein MeCP2 is essential for embryonic development in the mouse
40. The establishment and maintenance of DNA methylation patterns in mouse somatic cells
41. Cytosine methylation and mammalian development
42. Bisulfite sequencing in preimplantation embryos: DNA methylation profile of the upstream region of the mouse imprinted H19 Gene
43. The majority of methylated deoxycytidines in human DNA are not in the CpG dinucleotide
44. Epigenetics: Regulation through repression
45. Regulation of gene expression in the mouse oocyte and early preimplantation embryo: Developmental changes in Sp1 and TATA box-binding protein, TBP
46. The mutational burden of 5-methylcytosine
47. A candidate mammalian DNA methyltransferase related to pmt1p of fission yeast