The heterocyclic amine, 3-amino-1,4-dimethyl-5H-pyrido[4,3-b]indole induces apoptosis in cocultures of rat parenchymal and nonparenchymal liver cells

Toxicology and Applied Pharmacology

Volumn 177, Issue 1, 2001, Pages 59-67

  Ashida, Hitoshi ^a   Kihara, Kaori ^a   Nonaka, Yuji ^a   Fukuda, Itsuko ^a   Shiotani, Bunsyo ^a   Hashimoto, Takashi ^a  

^a KOBE UNIVERSITY   (Japan)

Author keywords

Apoptosis; Hepatocytes; Heterocyclic amine; Nonparenchymal cells; Rat; Trp P 1

Indexed keywords

3 AMINO 1,4 DIMETHYL 5H PYRIDO[4,3 B]INDOLE; CASPASE 3; CASPASE 8; CASPASE 9; CASPASE INHIBITOR; CYTOCHROME C; DNA FRAGMENT; ENDONUCLEASE; HETEROCYCLIC AMINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIVER PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BID; PROTEIN KINASE C; PROTEIN P53; PYRROLIDINE DITHIOCARBAMATE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; COCULTURE; CONTROLLED STUDY; ENZYME ACTIVATION; INCUBATION TIME; LIVER CELL; LIVER MITOCHONDRION; LIVER PARENCHYMA; MALE; NONHUMAN; PROTEIN DEGRADATION; PROTEIN DNA BINDING; PROTEIN EXPRESSION; RAT; WESTERN BLOTTING;

EID: 0035891488     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1006/taap.2001.9290     Document Type: Article

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