Contribution of anaphylatoxin C5a to late airway responses after repeated exposure of antigen to allergic rats

Journal of Immunology

Volumn 167, Issue 8, 2001, Pages 4651-4660

  Abe, M ^a   Shibata, K ^a   Akatsu, H ^a   Shimizu, N ^a   Sakata, N ^a   Katsuragi, T ^a   Okada, H ^a  

^a FUKUOKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C3A; COMPLEMENT COMPONENT C3A [DEARGININE]; COMPLEMENT COMPONENT C5A; COMPLEMENT COMPONENT C5A RECEPTOR; COMPLEMENT COMPONENT C5A RECEPTOR ANTAGONIST; COMPLEMENT COMPONENT C5A[DEARGININE]; COMPLEMENT INHIBITOR; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT 1; MESSENGER RNA; NAFAMSTAT MESILATE; OVALBUMIN; SOLUBLE COMPLEMENT RECEPTOR 1; UNCLASSIFIED DRUG;

ALLERGIC ASTHMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN ANTIBODY COMPLEX; ARTICLE; BRONCHUS MUCOSA; CONTROLLED STUDY; CYTOKINE PRODUCTION; EOSINOPHIL; IMMUNOPHARMACOLOGY; LUNG RESISTANCE; MALE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; RAT; RECEPTOR UPREGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS;

EID: 0035887920     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.167.8.4651     Document Type: Article

References (37)

1. Inflammatory mediators of asthma: An update
2. Bronchial provocation test in the etiologic diagnosis and analysis of asthma
3. Neutrophil chemotactic activity in antigen-induced late asthmatic reactions
4. Bronchoalveolar eosinophilia during allergen-induced late asthmatic reactions
5. Eosinophilic inflammation in asthma
6. Treatment of chronic stable asthma with drugs active on the 5-lipoxygenase pathway
7. Asthma: From bronchoconstriction to airways inflammation and remodeling
8. Repeated allergen challenge as a new research model for studying allergic reactions
9. Absence of late airway response despite increased airway responsiveness and eosinophilia in a murine model of asthma
10. Late asthmatic responses
11. Effect of local allergen priming on early, late, delayed-phase, and epicutaneous skin reactions
12. Role of the complement system in pulmonary disorders
13. A role for the C3a anaphylatoxin receptor in the effector phase of asthma
14. Guinea pigs with a natural C3a-receptor defect exhibit decreased bronchoconstriction in allergic airway disease: Evidence for an involvement of the C3a anaphylatoxin in the pathogenesis of asthma
15. Structure and function of anaphylatoxins
16. C5a-mediated release of interleukin 6 by human monocytes
17. Identification of neutrophil chemotactic factors in bronchoalveolar lavage fluid of asthmatic patients
18. Is complement activation a factor in bronchial asthma?
19. Soluble human complement receptor type 1: In vivo inhibitor of complement suppressing post-ischemic myocardial inflammation and necrosis
20. Therapeutic inhibition of the complement system
21. Systemic complement system depletion does not inhibit cellular accumulation in antihistamine pretreated allergic guinea pig lung
22. Development of C5a receptor antagonists: Differential loss of functional responses
23. Glucocorticoid- mediated gene suppression of rat cytokine-induced neutrophil chemoattractant CINC/gro, a member of the interleukin-8 family, through impairment of NF-κB activation
24. Isolation of three anaphylatoxins from complement-activated human serum
25. Diagnostic complement fixation
26. Use of an analog on-line computer for the evaluation of pulmonary resistance and dynamic compliance in the anesthetized dog
27. Cloning and characterization of rat C3a receptor: Differential expression of rat C3a and C5a receptors by LPS stimulation
28. cDNA cloning and characterization of rat C5a anaphylatoxin receptor
29. Pulmonary function changes and increased Th-2 cytokine expression and nuclear factor kB activation in the lung after sensitization and allergen challenge in brown Norway rats
30. 4 receptor antagonist on antigen-induced pulmonary reaction
31. Immunologic studies in allergen-induced latephase asthmatic reactions
32. Late-phase inflammation: Influence on morbidity
33. Identification of complement factor 5 as a susceptibility locus for experimental allergic asthma
34. Cross-desensitization of receptors for peptide chemoattractants, characterization of a new form of leukocyte regulation
35. Neutrophil priming by cytokines and vitamin D binding protein (Gc-globulin): Impact on C5a-mediated chemotaxis, degranulation and respiratory burst
36. Differential production of chemokines and their role in neutrophil infiltration in rat allergic inflammation
37. Intratracheal administration of anaphylatoxin C5a potentiates antigen-induced pulmonary reactions through the prolonged production of cysteinyl-leukotrienes