cDNA cloning and characterization of rat C5a anaphylatoxin receptor

Microbiology and Immunology

Volumn 41, Issue 7, 1997, Pages 575-580

  Akatsu, Hiroyasu ^a,b   Miwa, Takashi ^a,b   Sakurada, Chikai ^a,c   Fukuoka, Yoshihiro ^d,e   Ember, Julia A ^d   Yamamoto, Takayuki ^a   Hugli, Tony E ^d   Okada, Hidechika ^b  

^a Fukushimura Hospital   (Japan)

^b NAGOYA CITY UNIV MEDICAL SCHOOL   (Japan)

^c DAIICHI UNIVERSITY OF PHARMACY   (Japan)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

^e TOHOKU UNIVERSITY   (Japan)

Author keywords

C5a receptor (C5aR); cDNA cloning; Lipopolysaccharide (LPS)

Indexed keywords

ANAPHYLATOXIN; COMPLEMENT COMPONENT C5A; COMPLEMENT RECEPTOR; COMPLEMENTARY DNA;

ANAPHYLAXIS; ARTICLE; BINDING COMPETITION; GENE SEQUENCE; HUMAN; MOLECULAR CLONING; NONHUMAN; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; TISSUE DISTRIBUTION;

EID: 0030872386     PISSN: 03855600     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1348-0421.1997.tb01894.x     Document Type: Article

References (15)

1. Cochrane, C.G., and Muller-Eberhard, H.J. 1968. The derivation of two distinct anaphylatoxin activities from the third and fifth components of human complement. J. Exp. Med. 127: 371-386.
2. Fernandez, H.N., Henson, P.M., Otani, A., and Hugli, T.E. 1978. Chemotactic response to human C3a and C5a anaphylatoxins. I. Evaluation of C3a and C5a leukotaxis in vitro and under stimulated in vivo conditions. J. Immunol. 120: 109-115.
3. Fukuoka, Y., and Hugli, T.E. 1988. Demonstration of a specific C3a receptor on guinea pig platelets. J. Immunol. 140: 3496-3501.
4. Gasque, P., Chan, P., Fontaine, M., Ischenko, A., Lamacz, M., Götze, O., and Morgan, P. 1995. Identification and characterization of the complement C5a anaphylatoxin receptor on human astrocytes. J. Immunol. 155: 4882-4889.
5. Gerard, C., Bao, L., Orozco, O., Pearson, M., Kunz, D., and Gerard, N.P. 1992. Strucrural diversity in the extracellular faces of peptidergic G-protein-coupled receptors. Molecular cloning of the mouse C5a anaphylatoxin receptor. J. Immunol. 149: 2600-2606.
6. Gerard, N.P., and Gerard, C. 1991. The chemotactic receptor for human C5a anaphyla-toxin. Nature 349: 614-617.
7. Goldstein, I.M., and Weissmann, G. 1974. Generation of C5-derived lysosomal enzymereleasing activity (C5a) by lysates of leukocyte lysosomes. J. Immunol. 113: 1583-1588.
8. Haviland, D.L., McCoy, R.L., Whitehead, W.T., Akama, H., Molmenti, E.P., Brown, A., Haviland, J.C., Parks, W.C., Perlmutter, D.H., and Wetsel, R.A. 1995. Cellular expression of the C5a anaphylatoxin receptor (C5aR): demonstration of C5aR on nonmyeloid cells of the liver and lung. J. Immunol. 154: 1861-1869.
9. Höpken, U.E., Bao, L., Gerard, N.P., and Gerard, C. 1996. The C5a chemoattractant receptor mediates mucosal defence to infection. Nature 383: 86-89.
10. Perret, J.J., Raspe, E., Vassart, G., and Parmentier, M. 1992. Cloning and functional expression of the canine anaphylatoxin C5a receptor. Evidence for high interspecies variability. Biochem. J. 288: 911-917.
11. Prossnitz, E.R., Quehenberger, O., Cochrane, C.G., and Ye, R.D. 1991. Transmembrane signalling by the N-formyl peptide receptor in stably transfected fibroblasts. Biochem. Biophys. Res. Commun. 179: 471-476.
12. Robbins, R.A., Russ, W.D., Rasmussen, J.K., and Clayton, M.M. 1987. Activation of the complement system in the adult respiratory distress syndrome. Am. Rev. Respir. Dis. 135: 651-658.
13. Sacks, T., Moldow, C.F., Craddock, P.R., Bowers, T.K., and Jacob, H.S. 1978. Oxygen radicals mediate cell damage by complement-stimulated granulocytes. An in vitro model of immune vascular damage. J. Clin. Invest. 61: 1161-1167.
14. Shin, H.S., Snyderman, R., Friedman, E., Mellors, A., and Mayer, M.M. 1968. Chemotactic and anaphylatoxic fragment cleaved from the fifth component of guinea pig complement. Science 162: 361-363.
15. Thomas, P.S. 1983. Hybridization of denatured RNA transferred or dotted nitrocellulose paper. Methods Enzymol. 100: 255-266.