Cutting edge: The absence of C3 demonstrates a role for complement in Th2 effector functions in a murine model of pulmonary allergy

Journal of Immunology

Volumn 167, Issue 8, 2001, Pages 4141-4145

  Drouin, S M ^a   Corry, D B ^a   Kildsgaard, J ^a   Wetsel, R A ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; COMPLEMENT COMPONENT C3; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G1; INTERLEUKIN 4;

AIRWAY OBSTRUCTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTHMA; BRONCHUS HYPERREACTIVITY; CELL ACTIVATION; CONTROLLED STUDY; EFFECTOR CELL; IMMUNOGLOBULIN PRODUCTION; LOEFFLER PNEUMONIA; LUNG LAVAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TH2 CELL;

EID: 0035887610     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.167.8.4141     Document Type: Article

References (33)

1. Immunologic basis of antigen-induced airway hyperresponsiveness
2. Bronchial reactivity to inhaled histamine: A method and clinical survey
3. Relation between airway responsiveness and serum IgE in children with asthma and in apparently normal children
4. The relationship between airway inflammation and bronchial hyperresponsiveness
5. Eosinophilic inflammation in asthma
6. Bronchoalveolar eosinophilia during allergen-induced late asthmatic reactions
7. IL-12/IL-13 axis in allergic asthma
8. Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity
9. Requirements for allergen-induced airway hyperreactivity in T and B cell-deficient mice
10. 2
11. IL-4 is required to generate and sustain in vivo IgE responses
12. Complementing asthma
13. Complement anaphylatoxins (C3a, C4a, C5a) and their receptors (C3aR, C5aR/CD88) as therapeutic targets in inflammation
14. ELISA of complement C3a in bronchoalveolar lavage fluid
15. Effect of exercise on complement activity
16. A role for the C3a anaphylatoxin receptor in the effector phase of asthma
17. Genome-wide search for asthma susceptibility loci in a founder population: The Collaborative Study on the Genetics of Asthma
18. Cutting edge: Guinea pigs with a natural C3a-receptor defect exhibit decreased bronchoconstriction in allergic airway disease: Evidence for an involvement of the C3a anaphylatoxin in the pathogenesis of asthma
19. Trimellitic anhydride-induced allergic response in the guinea pig lung involves antibody-dependent and -independent complement system activation
20. Trimellitic anhydride-induced allergic response in the lung: Role of the complement system in cellular changes
21. Expression of the complement anaphylatoxin C3a and C5a receptors on bronchial epithelial and smooth muscle cells in models of sepsis and asthma
22. Genetic disruption of the murine complement C3 promoter region generates deficient mice with extrahepatic expression of C3 mRNA
23. A murine model of allergic bronchopulmonary aspergillosis with elevated eosinophils and IgE
24. Interleukin-10 is a natural suppressor of cytokine production and inflammation in a murine model of allergic bronchopulmonary aspergillosis
25. A comparison of C3a and C5a-mediated stable adhesion of rolling eosinophils in postcapillary venules and transendothelial migration in vitro and in vivo
26. C3d of complement as a molecular adjuvant: Bridging innate and acquired immunity
27. Mechanism and regulation of immunoglobulin isotype switching
28. Selective suppression of IL-12 production by chemoattractants
29. Identification of complement factor 5 as a susceptibility locus for experimental allergic asthma
30. + T cells, eosinophils, and mast cells in bronchial biopsies obtained from atopic and nonatopic (intrinsic) asthmatics
31. Requirements for C5a receptormediated IL-4 and IL-13 production and leukotriene C4 generation in human basophils
32. Activated human T lymphocytes express a functional C3a receptor
33. Crry/p65, a membrane complement regulatory protein, has costimulatory properties on mouse T cells