Maintenance of Cdc42 GDP-bound state by Rho-GDI inhibits MAP kinase activation by the exchange factor Ras-GRF. Evidence for Ras-GRF function being inhibited by Cdc42-GDP but unaffected by Cdc42-GTP

Journal of Biological Chemistry

Volumn 276, Issue 24, 2001, Pages 21878-21884

  Arozarena, Imanol ^a   Matallanas, David ^a   Crespo, Piero ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; ENZYME INHIBITION; ENZYME KINETICS; MOLECULAR BIOLOGY;

INHIBITORY EFFECTS;

BIOCHEMISTRY;

ACK1 PROTEIN; GEF DBL PROTEIN; GROWTH HORMONE RELEASING FACTOR; GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATASE; GUANOSINE TRIPHOSPHATE; IONOMYCIN; LYSOPHOSPHATIDIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; MIXED LINEAGE KINASE 3; P21 ACTIVATED KINASE 1; PROTEIN; PROTEIN CDC42; RAS PROTEIN; RHO FACTOR; UNCLASSIFIED DRUG; WASP PROTEIN; LYSOPHOSPHOLIPID; RECOMBINANT PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHO GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME MECHANISM; GENE OVEREXPRESSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; SIGNAL TRANSDUCTION; ANIMAL; CELL STRAIN COS1; CERCOPITHECUS; GENETIC TRANSFECTION; KINETICS; METABOLISM; PHYSIOLOGY; SITE DIRECTED MUTAGENESIS;

ANIMALIA;

ANIMALS; CDC42 GTP-BINDING PROTEIN; CERCOPITHECUS AETHIOPS; COS CELLS; GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; IONOMYCIN; KINETICS; LYSOPHOSPHOLIPIDS; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASES; MUTAGENESIS, SITE-DIRECTED; RAS-GRF1; RECOMBINANT PROTEINS; RHO GTP-BINDING PROTEINS; TRANSFECTION;

EID: 0035877781     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M011383200     Document Type: Article

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