Two Functionally Distinct Steps Mediate High Affinity Binding of U1A Protein to U1 Hairpin II RNA

Journal of Biological Chemistry

Volumn 276, Issue 24, 2001, Pages 21476-21481

  Katsamba, Phinikoula S ^a   Myszka, David G ^b   Laird Offringa, Ite A ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CONCENTRATION (PROCESS); DNA; ELECTROSTATICS; ENZYME KINETICS; RNA; SUBSTITUTION REACTIONS;

MUTANTS;

PROTEINS;

DNA BINDING PROTEIN; DOUBLE STRANDED RNA; PROTEIN; PROTEIN U1A; RNA; U1 HAIRPIN II RNA; UNCLASSIFIED DRUG; ARGININE; LYSINE; RECOMBINANT PROTEIN; RNA BINDING PROTEIN; SMALL NUCLEAR RIBONUCLEOPROTEIN; SMALL NUCLEAR RNA; U1 SMALL NUCLEAR RNA; U1A PROTEIN;

AMINO ACID SUBSTITUTION; ARTICLE; BETA SHEET; BINDING AFFINITY; COMPLEX FORMATION; HYDROGEN BOND; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN RNA BINDING; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; RECEPTOR BINDING; RNA STRUCTURE; TARGET CELL; AMINO ACID SEQUENCE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; ELECTRICITY; GENETIC PROCEDURES; HUMAN; KINETICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PROTEIN CONFORMATION; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARGININE; BASE SEQUENCE; BINDING SITES; BIOSENSING TECHNIQUES; ELECTROSTATICS; HUMANS; HYDROGEN BONDING; KINETICS; LYSINE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NUCLEIC ACID CONFORMATION; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; RIBONUCLEOPROTEIN, U1 SMALL NUCLEAR; RNA, SMALL NUCLEAR; RNA-BINDING PROTEINS;

EID: 0035877589     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M101624200     Document Type: Article

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