Up-regulation of a thermogenesis-related gene (UCP1) and down-regulation of PPARγ and aP2 genes in adipose tissue: Possible features of the antiobesity effects of a β3-adrenergic agonist

Biochemical Pharmacology

Volumn 61, Issue 12, 2001, Pages 1471-1478

  Margareto, Javier ^a   Larrarte, Eider ^a   Marti, Amelia ^a   Martinez, J Alfredo ^a  

^a UNIVERSITY OF NAVARRA   (Spain)

Author keywords

Adipogenesis; AP2; Diet induced obesity; Peroxisome proliferator activated transcription factor; Retinoid X receptors; Thermogenesis; Uncoupling proteins; 3 Adrenergic agonist

Indexed keywords

BETA ADRENERGIC RECEPTOR STIMULATING AGENT; FATTY ACID BINDING PROTEIN; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; RECEPTOR SUBUNIT; RETINOIC ACID RECEPTOR; RETINOID X RECEPTOR; TERTATOLOL; UNCOUPLING PROTEIN 1; UNCOUPLING PROTEIN 2; UNCOUPLING PROTEIN 3;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY MASS; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; FEMALE; GENE EXPRESSION REGULATION; GENE FUNCTION; GENETIC TRANSCRIPTION; LIPID DIET; LIPID STORAGE; LIPOLYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR DOWN REGULATION; RECEPTOR GENE; THERMOGENESIS; TISSUE LEVEL; WEIGHT GAIN; WHITE ADIPOSE TISSUE;

ADAPTOR PROTEIN COMPLEX 2; ADAPTOR PROTEIN COMPLEX ALPHA SUBUNITS; ADAPTOR PROTEINS, VESICULAR TRANSPORT; ADIPOSE TISSUE; ADRENERGIC BETA-AGONISTS; ANIMALS; ANTI-OBESITY AGENTS; BODY TEMPERATURE; BODY WEIGHT; CARRIER PROTEINS; DOWN-REGULATION; FEMALE; ION CHANNELS; LEPTIN; MEMBRANE PROTEINS; MITOCHONDRIAL PROTEINS; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC, BETA-3; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, RETINOIC ACID; RETINOID X RECEPTORS; RNA, MESSENGER; TRANSCRIPTION FACTORS; UP-REGULATION;

EID: 0035877169     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(01)00562-7     Document Type: Article

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