-
1
-
-
0027711598
-
Oligonucleotide analogs containing dephospho-internucleoside linkages
-
Uhlmann, E. and Peyman, A. (1993) Oligonucleotide analogs containing dephospho-internucleoside linkages. Methods Mol. Biol., 20, 355-389.
-
(1993)
Methods Mol. Biol.
, vol.20
, pp. 355-389
-
-
Uhlmann, E.1
Peyman, A.2
-
2
-
-
0025941284
-
Sequence-selective DNA recognition by synthetic ligands
-
Nielsen, P.E. (1991) Sequence-selective DNA recognition by synthetic ligands. Bioconjug. Chem., 2, 1-12.
-
(1991)
Bioconjug. Chem.
, vol.2
, pp. 1-12
-
-
Nielsen, P.E.1
-
3
-
-
0041582974
-
Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide
-
Zamecnik, P.C. and Stephenson, M.L. (1978) Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide. Proc. Natl Acad. Sci. USA, 75, 280-284.
-
(1978)
Proc. Natl Acad. Sci. USA
, vol.75
, pp. 280-284
-
-
Zamecnik, P.C.1
Stephenson, M.L.2
-
4
-
-
0033990403
-
Progress in antisense technology: The end of the beginning
-
Crooke, S.T. (2000) Progress in antisense technology: the end of the beginning. Methods Enzymol., 313, 3-45.
-
(2000)
Methods Enzymol.
, vol.313
, pp. 3-45
-
-
Crooke, S.T.1
-
5
-
-
0345706517
-
Antisense oligonucleotides
-
Mesmaeker, A., Haner, R., Martin, P. and Moser, H. (1995) Antisense oligonucleotides Acc. Chem. Res., 28, 366-374.
-
(1995)
Acc. Chem. Res.
, vol.28
, pp. 366-374
-
-
Mesmaeker, A.1
Haner, R.2
Martin, P.3
Moser, H.4
-
6
-
-
0027254030
-
Antisense oligonucleotides made of 2'-O-alkyl RNA: Their properties and applications in RNA biochemistry
-
Lamond, A.I. and Sproat, B.S. (1993) Antisense oligonucleotides made of 2'-O-alkyl RNA: their properties and applications in RNA biochemistry. FEBS Lett., 325, 123-127.
-
(1993)
FEBS Lett.
, vol.325
, pp. 123-127
-
-
Lamond, A.I.1
Sproat, B.S.2
-
7
-
-
0032168909
-
Hybridization of peptide nucleic acid
-
Ratilainen, T., Holmen, A.,Tuite, E., Haaima, G., Christensen, L., Nielsen, P.E. and Norden, B. (1998) Hybridization of peptide nucleic acid. Biochemistry, 37, 12331-12342.
-
(1998)
Biochemistry
, vol.37
, pp. 12331-12342
-
-
Ratilainen, T.1
Holmen, A.2
Tuite, E.3
Haaima, G.4
Christensen, L.5
Nielsen, P.E.6
Norden, B.7
-
8
-
-
0033517730
-
Triplex formation of chemically modified homopyrimidine oligonucleotides: Thermodynamic and kinetic studies
-
Torigoe, H., Shimizume, R., Sarai, A. and Shindo, H. (1999) Triplex formation of chemically modified homopyrimidine oligonucleotides: thermodynamic and kinetic studies. Biochemistry, 38, 14653-14659.
-
(1999)
Biochemistry
, vol.38
, pp. 14653-14659
-
-
Torigoe, H.1
Shimizume, R.2
Sarai, A.3
Shindo, H.4
-
9
-
-
0028908157
-
Relative stabilities of triple helices composed of combinations of DNA, RNA and 2'-O-methyl-RNA backbones: Chimeric circular oligonucleotides as probes
-
Wang, S. and Kool, E.T. (1995) Relative stabilities of triple helices composed of combinations of DNA, RNA and 2'-O-methyl-RNA backbones: chimeric circular oligonucleotides as probes. Nucleic Acids Res., 23, 1157-1164.
-
(1995)
Nucleic Acids Res.
, vol.23
, pp. 1157-1164
-
-
Wang, S.1
Kool, E.T.2
-
10
-
-
0032750621
-
2'-carbohydrate modifications in antisense oligonucleotide therapy: Importance of conformation, configuration and conjugation
-
Manoharan, M. (1999) 2'-carbohydrate modifications in antisense oligonucleotide therapy: importance of conformation, configuration and conjugation. Biochim. Biophys. Acta, 1489, 117-130.
-
(1999)
Biochim. Biophys. Acta
, vol.1489
, pp. 117-130
-
-
Manoharan, M.1
-
11
-
-
0030727765
-
The ups and downs of nucleic acid duplex stability: Structure-stability studies on chemically-modified DNA:RNA duplexes
-
Freier, S.M. and Altmann, K.H. (1997) The ups and downs of nucleic acid duplex stability: structure-stability studies on chemically-modified DNA:RNA duplexes. Nucleic Acids Res., 25, 4429-4443.
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 4429-4443
-
-
Freier, S.M.1
Altmann, K.H.2
-
12
-
-
0027479864
-
Uniformly modified 2'-deoxy-2'-fluoro phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targets
-
Kawasaki, A.M., Casper, M.D., Freier, S.M., Lesnik, E.A., Zounes, M.C., Cummins, L.L., Gonzalez, C. and Cook, P.D. (1993) Uniformly modified 2'-deoxy-2'-fluoro phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targets. J. Med. Chem., 36, 831-841.
-
(1993)
J. Med. Chem.
, vol.36
, pp. 831-841
-
-
Kawasaki, A.M.1
Casper, M.D.2
Freier, S.M.3
Lesnik, E.A.4
Zounes, M.C.5
Cummins, L.L.6
Gonzalez, C.7
Cook, P.D.8
-
13
-
-
0033053332
-
Crystal structure and improved antisense properties of 2'-O-(2-methoxyethyl)-RNA
-
Teplova, M., Minasov, G., Tereshko, V., Inamati, G.B., Cook, P.D., Manoharan, M. and Egli, M. (1999) Crystal structure and improved antisense properties of 2'-O-(2-methoxyethyl)-RNA. Nat. Struct. Biol., 6, 535-539.
-
(1999)
Nat. Struct. Biol.
, vol.6
, pp. 535-539
-
-
Teplova, M.1
Minasov, G.2
Tereshko, V.3
Inamati, G.B.4
Cook, P.D.5
Manoharan, M.6
Egli, M.7
-
14
-
-
0026323898
-
Synthesis and biophysical and biological evaluation of 2'-modified antisense oligonucleotides
-
Guinosso, C., Hoke, G., Frier, S., Martin, J., Ecker, D., Mirabelli, C., Crooke, S. and Cook, P. (1991) Synthesis and biophysical and biological evaluation of 2'-modified antisense oligonucleotides. Nucl. Nucl., 10, 259-262.
-
(1991)
Nucl. Nucl.
, vol.10
, pp. 259-262
-
-
Guinosso, C.1
Hoke, G.2
Frier, S.3
Martin, J.4
Ecker, D.5
Mirabelli, C.6
Crooke, S.7
Cook, P.8
-
15
-
-
0029955524
-
Stereoselective synthesis of 2'-O-(2-methoxyethyl)ribonucleosides
-
Martin, P. (1996) Stereoselective synthesis of 2'-O-(2-methoxyethyl)ribonucleosides. Helv. Chim. Acta, 79, 1930-1938.
-
(1996)
Helv. Chim. Acta
, vol.79
, pp. 1930-1938
-
-
Martin, P.1
-
16
-
-
0030463954
-
2'-O-aminopropyl ribonucleotides: A zwitterionic modification that enhances the exonuclease resistance and biological activity of antisense oligonucleotides
-
Griffey, R.H., Monia, B.P., Cummins, L.L., Freier, S., Greig, M.J., Guinosso, C.J., Lesnik, E., Manalili, S.M., Mohan, V., Owens, S. et al. (1996) 2'-O-aminopropyl ribonucleotides: a zwitterionic modification that enhances the exonuclease resistance and biological activity of antisense oligonucleotides. J. Med. Chem., 39, 5100-5109.
-
(1996)
J. Med. Chem.
, vol.39
, pp. 5100-5109
-
-
Griffey, R.H.1
Monia, B.P.2
Cummins, L.L.3
Freier, S.4
Greig, M.J.5
Guinosso, C.J.6
Lesnik, E.7
Manalili, S.M.8
Mohan, V.9
Owens, S.10
-
17
-
-
12644302203
-
Pharmacokinetic properties of several novel oligonucleotide analogs in mice
-
Crooke, S., Graham, M., Zukerman, J., Brooks, D., Conklin, B., Cummins, L., Greig, M., Guinosso, C., Kornburst, D., Manoharan, M. et al. (1996) Pharmacokinetic properties of several novel oligonucleotide analogs in mice. J. Pharmacol. Exp. Ther., 277, 923-937.
-
(1996)
J. Pharmacol. Exp. Ther.
, vol.277
, pp. 923-937
-
-
Crooke, S.1
Graham, M.2
Zukerman, J.3
Brooks, D.4
Conklin, B.5
Cummins, L.6
Greig, M.7
Guinosso, C.8
Kornburst, D.9
Manoharan, M.10
-
18
-
-
0027204049
-
Oligodeoxynucleotides containing 2'-O-modified adenosine: Synthesis and effects on stability of DNA:RNA duplexes
-
Lesnik, E.A., Guinosso, C.J., Kawasaki, A.M., Sasmor, H., Zounes, M., Cummins, L.L., Ecker, D.J., Cook, P.D. and Freier, S.M. (1993) Oligodeoxynucleotides containing 2'-O-modified adenosine: synthesis and effects on stability of DNA:RNA duplexes. Biochemistry, 32, 7832-7838.
-
(1993)
Biochemistry
, vol.32
, pp. 7832-7838
-
-
Lesnik, E.A.1
Guinosso, C.J.2
Kawasaki, A.M.3
Sasmor, H.4
Zounes, M.5
Cummins, L.L.6
Ecker, D.J.7
Cook, P.D.8
Freier, S.M.9
-
19
-
-
0030463954
-
2'-O-aminopropyl ribonucleotides: A zwitterionic modification that enhances the exonuclease resistance and biological activity of antisense oligonucleotides
-
Griffey, R.H., Monia, B.P., Cummins, L.L., Freier, S., Greig, M.J., Guinosso, C.J., Lesnik, E., Manalili, S.M., Mohan, V., Owens, S. et al. (1996) 2'-O-aminopropyl ribonucleotides: a zwitterionic modification that enhances the exonuclease resistance and biological activity of antisense oligonucleotides. J. Med. Chem., 39, 5100-5109.
-
(1996)
J. Med. Chem.
, vol.39
, pp. 5100-5109
-
-
Griffey, R.H.1
Monia, B.P.2
Cummins, L.L.3
Freier, S.4
Greig, M.J.5
Guinosso, C.J.6
Lesnik, E.7
Manalili, S.M.8
Mohan, V.9
Owens, S.10
-
20
-
-
0027168725
-
Evaluation of 2'-modified oligonucleotides containing 2'-deoxy gaps as antisense inhibitors of gene expression
-
Monia, B.P., Lesnik, E.A., Gonzalez, C., Lima, W.F., McGee, D., Guinosso, C.J., Kawasaki, A.M., Cook, P.D. and Freier, S.M. (1993) Evaluation of 2'-modified oligonucleotides containing 2'-deoxy gaps as antisense inhibitors of gene expression. J. Biol. Chem., 268, 14514-14522.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 14514-14522
-
-
Monia, B.P.1
Lesnik, E.A.2
Gonzalez, C.3
Lima, W.F.4
McGee, D.5
Guinosso, C.J.6
Kawasaki, A.M.7
Cook, P.D.8
Freier, S.M.9
-
21
-
-
0013769174
-
Theory of the effects of concentration and chain length on helix-coil equilibria in two-stranded nucleic acids
-
Applequist, J. and Damle, V. (1963) Theory of the effects of concentration and chain length on helix-coil equilibria in two-stranded nucleic acids. J. Chem. Phys., 39, 2719-2721.
-
(1963)
J. Chem. Phys.
, vol.39
, pp. 2719-2721
-
-
Applequist, J.1
Damle, V.2
-
22
-
-
0024804759
-
Absorbance melting curves of RNA
-
Puglisi, J.D. and Tinoco, I.,Jr (1989) Absorbance melting curves of RNA. Methods Enzymol., 180, 304-325.
-
(1989)
Methods Enzymol.
, vol.180
, pp. 304-325
-
-
Puglisi, J.D.1
Tinoco I., Jr.2
-
23
-
-
0029121625
-
Relative thermodynamic stability of DNA, RNA and DNA:RNA hybrid duplexes: Relationship with base composition and structure
-
Lesnik, E.A. and Freier, S.M. (1995) Relative thermodynamic stability of DNA, RNA and DNA:RNA hybrid duplexes: relationship with base composition and structure. Biochemistry, 34, 10807-10815.
-
(1995)
Biochemistry
, vol.34
, pp. 10807-10815
-
-
Lesnik, E.A.1
Freier, S.M.2
-
25
-
-
0027469785
-
Sensitive fluorescence-based lhermodynamic and kinetic measurements of DNA hybridization in solution
-
Morrison, L.E. and Stols, L.M. (1993) Sensitive fluorescence-based lhermodynamic and kinetic measurements of DNA hybridization in solution. Biochemistry, 32, 3095-3104.
-
(1993)
Biochemistry
, vol.32
, pp. 3095-3104
-
-
Morrison, L.E.1
Stols, L.M.2
-
26
-
-
0034604217
-
Thermodynamics of sequence-specific binding of PNA to DNA
-
Ratilainen, T., Holmen, A., Tuite, E., Nielsen, P.E. and Norden, B. (2000) Thermodynamics of sequence-specific binding of PNA to DNA. Biochemistry, 39, 7781-7791.
-
(2000)
Biochemistry
, vol.39
, pp. 7781-7791
-
-
Ratilainen, T.1
Holmen, A.2
Tuite, E.3
Nielsen, P.E.4
Norden, B.5
-
27
-
-
0023201684
-
Stereochemical features controlling binding and intrinsic activity properties of benzodiazepine-receptor ligands
-
Borea, P.A., Gilli, G., Bertolasi, V. and Ferretti, V. (1987) Stereochemical features controlling binding and intrinsic activity properties of benzodiazepine-receptor ligands. Mol. Pharmacol., 31, 334-344.
-
(1987)
Mol. Pharmacol.
, vol.31
, pp. 334-344
-
-
Borea, P.A.1
Gilli, G.2
Bertolasi, V.3
Ferretti, V.4
-
28
-
-
0342618762
-
Kinetics for hybridization of peptide nucleic acids (PNA) with DNA and RNA studied with the BlAcore technique
-
Jensen, K.K., Orum, H., Nielsen, P.E. and Norden, B. (1997) Kinetics for hybridization of peptide nucleic acids (PNA) with DNA and RNA studied with the BlAcore technique. Biochemistry, 36, 5072-5077.
-
(1997)
Biochemistry
, vol.36
, pp. 5072-5077
-
-
Jensen, K.K.1
Orum, H.2
Nielsen, P.E.3
Norden, B.4
-
29
-
-
0026621339
-
Implication of RNA structure on antisense oligonucleotide hybridization kinetics
-
Lima, W.F., Monia, B.P., Ecker, D.J. and Freier, S.M. (1992) Implication of RNA structure on antisense oligonucleotide hybridization kinetics. Biochemistry, 31, 12055-12061.
-
(1992)
Biochemistry
, vol.31
, pp. 12055-12061
-
-
Lima, W.F.1
Monia, B.P.2
Ecker, D.J.3
Freier, S.M.4
-
30
-
-
0030018227
-
Ionic effects on the stability conformation of peptide nucleic acid complexes
-
Tomac, S., Sarkar, M., Ratilainen, T., Wittung, P., Nielsen, P., Norden, B. and Graslund, A. (1996) Ionic effects on the stability conformation of peptide nucleic acid complexes. J. Am. Chem. Soc., 118, 5544-5552.
-
(1996)
J. Am. Chem. Soc.
, vol.118
, pp. 5544-5552
-
-
Tomac, S.1
Sarkar, M.2
Ratilainen, T.3
Wittung, P.4
Nielsen, P.5
Norden, B.6
Graslund, A.7
-
31
-
-
1542606746
-
Kinetic measurements of DNA hybridization on an oligonucleotide-immobilized 27-MHz quartz crystal microbalance
-
Okahata, Y., Kawase, M., Niikura, K., Ohtake, F., Furusawa, H. and Ebara, Y. (1998) Kinetic measurements of DNA hybridization on an oligonucleotide-immobilized 27-MHz quartz crystal microbalance. Anal. Chem., 70, 1288-1296.
-
(1998)
Anal. Chem.
, vol.70
, pp. 1288-1296
-
-
Okahata, Y.1
Kawase, M.2
Niikura, K.3
Ohtake, F.4
Furusawa, H.5
Ebara, Y.6
|