Direct interaction of a brain voltage-gated K+ channel with syntaxin 1a: Functional impact on channel gating

Journal of Neuroscience

Volumn 21, Issue 6, 2001, Pages 1964-1974

  Fili, Oded ^a   Michaelevski, Itzhak ^a   Bledi, Yaniv ^b   Chikvashvili, Dodo ^a   Singer Lahat, Dafna ^a   Boshwitz, Hassia ^b   Linial, Michal ^b   Lotan, Ilana ^a  

^a TEL AVIV UNIVERSITY   (Israel)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Gating; K+ channel; Kv channel; Kv1.1 subunits; Kv subunits; Potassium channel; Rat brain synaptosomes; SNARE complex; Syntaxin 1A; Xenopus oocytes

Indexed keywords

NEUROTRANSMITTER; POTASSIUM CHANNEL; PROTEIN SUBUNIT; SYNAPTOSOMAL ASSOCIATED PROTEIN 25; SYNAPTOTAGMIN; SYNTAXIN;

ANIMAL CELL; ARTICLE; BRAIN SYNAPTOSOME; CHANNEL GATING; CONCENTRATION RESPONSE; CONTROLLED STUDY; GENE OVEREXPRESSION; NERVE CELL EXCITABILITY; NEUROTRANSMITTER RELEASE; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; XENOPUS;

EID: 0035869482     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.21-06-01964.2001     Document Type: Article

References (57)

1. The biochemistry of neurotransmitter secretion
2. SNAREs and the specificity of transport vesicle targeting
3. Syntaxin: A synaptic protein implicated in docking of synaptic vesicles at presynaptic active zones
4. Syntaxin modulation of calcium channels in cortical synaptosomes as revealed by botulinum toxin C1
5. Functional impact of syntaxin on gating of N-type and Q-type calcium channels
6. 2+ channels
7. Members of the SNARE hypothesis are associated with cortical granule exocytosis in the sea urchin egg
8. Expression of exogenous ion channels and neurotransmitter receptors in RNA-injected xenopus oocytes
9. A conformational switch in syntaxin during exocytosis: Role of mune18
10. + channel inactivation, spike broadening, and after-hyperpolarization in Kvbeta1.1-deficient mice with impaired learning
11. Neurotransmitter release: Four years of SNARE complexes
12. SNAREs and NSF in targeted membrane fusion
13. Increase in syntaxin 1B and glutamate release in mossy fibre terminals following induction of LTP in the dentate gyrus: A candidate molecular mechanism underlying transsynaptic plasticity
14. Depolarization affects the binding properties of muscarinic acetylcholine receptors and their interaction with proteins of the exocytotic apparatus
15. Phosphorylation by protein kinase A of RCK1 K+ channels expressed in Xenopus oocytes
16. G protein modulation of N-type calcium channels is facilitated by physical interactions between syntaxin 1A and Gβγ
17. Inactivation of a voltage-dependent K+ channel by beta subunit. Modulation by a phosphorylation-dependent interaction between the distal C terminus of alpha subunit and cytoskeleton
18. Fast inactivation of a brain K+ channel composed of Kv1.1 and Kvbeta1.1 subunits modulated by G protein beta gamma subunits
19. Regulation of RCK1 currents with a cAMP analog via enhanced protein synthesis and direct channel phosphorylation
20. Deletion of the N-terminus of a K+ channel brings about short-term modulation by cAMP and beta 1-adrenergic receptor activation
21. Phosphorylation of a K+ channel alpha subunit modulates the inactivation conferred by a beta subunit. Involvement of cytoskeleton
22. Activation of a metabotropic glutamate receptor and protein kinase C reduce the extent of inactivation of the K+ channel Kv1.1/Kvbeta1.1 via dephosphorylation of Kv1.1
23. A tobacco syntaxin with a role in hormonal control of guard cell ion channels
24. SNARE proteins: Why so many, why so few?
25. Deciphering neuronal secretion: Tools of the trade
26. Voltage-dependent interaction between the muscarinic ACh receptor and proteins of the exocytotic machinery
27. Ion channels in presynaptic nerve terminals and control of transmitter release
28. Reversible antisense inhibition of Shaker-like Kv1.1 potassium channel expression impairs associative memory in mouse and rat
29. Expression and functional role of syntaxin 1/HPC-1 in pancreatic beta cells. Syntaxin 1A, but not 1B, plays a negative role in regulatory insulin release pathway
30. Syntaxin 1A inhibits CFTR chloride channels by means of domain-specific protein-protein interactions
31. Rapid kinetics of potassiumevoked release of acetylcholine from rat brain synaptosomes: Analysis by rapid superfusion
32. Modulation by protein kinase C activation of rat brain delayedrectifier K+ channel expressed in Xenopus oocytes
33. Syntaxin 1A inhibits regulated CFTR trafficking in Xenopus oocytes
34. Regulation of the amiloride-sensitive epithelial sodium channel by syntaxin 1A
35. Inactivation properties of voltage-gated K+ channels altered by presence of beta-subunit
36. Isoform-specific interaction of the alpha1A subunits of brain Ca2+ channels with the presynaptic proteins syntaxin and SNAP-25
37. + channel α- and β-subunit polypeptides in rat brain
38. Presynaptic potassium channels
39. Short-term synaptic plasticity is altered in mice lacking synapsin I
40. Direct interaction between synaptotagmin and the intracellular loop I-II of neuronal voltage-sensitive sodium channels
41. Interaction of syntaxins with the amiloride-sensitive epithelial sodium channel
42. Membrane trafficking in the presynaptic nerve terminal
43. Cellular and subcellular localization of syntaxin-like immunoreactivity in the rat striatum and cortex
44. Presynaptic A-current based on heteromultimeric K+ channels detected in vivo
45. Identification of a syntaxin-binding site on N-type calcium channels
46. Calcium-dependent interaction of N-type calcium channels with the synaptic core complex
47. Physical link and functional coupling of presynaptic calcium channels and the synaptic vesicle docking/fusion machinery
48. Beta subunits promote K+ channel surface expression through effects early in biosynthesis
49. Acquired neuromyotonia: Evidence for autoantibodies directed against K+ channels of peripheral nerves
50. Modal behavior of the Kv1.1 channel conferred by the Kvbeta1.1 subunit and its regulation by dephosphorylation of Kv1.1
51. Imaging plasma membrane proteins in large membrane patches of Xenopus oocytes
52. SNAP receptors implicated in vesicle targeting and fusion
53. The synaptic vesicle cycle: A cascade of proteinprotein interactions
54. P/Q-type calcium channels mediate the activity-dependent feedback of syntaxin-1A
55. Immunohistochemical localization of five members of the Kv1 channel subunits: Contrasting subcellular locations and neuron-specific co-localizations in rat brain
56. Functional interaction of syntaxin and SNAP-25 with voltage-sensitive L- and N-type Ca2+ channels
57. The voltage sensitive Lc-type Ca2+ channel is functionally coupled to the exocytotic machinery