Solid-phase synthesis of 3H-Quinazolin-4-ones based on an aza Wittig-mediated annulation strategy

Synlett

Volumn , Issue 12, 1998, Pages 1405-1407

  Villalgordo, José M ^a,b   Obrecht, Daniel ^a,c   Chucholowsky, Alexander ^a  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

^b Facultat de Medicina   (Spain)

^c Polyphor Ltd   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0001003013     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-1998-1971     Document Type: Article

References (27)

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26. 3) data for compound 11d: 8.25-8.15 (m, 1H, arom.); 7.7-7.6 (m, 1H, arom.); 7.55-7.5 (m, 1H, arom.); 7.35-7.25 (m, 1H, arom.); 4.07 (t, 2H); 3.20 (t, 4H); 2.60 (t, br., 4H); 2.37 (s, 3H); 1.85-1.70 (m, 2H); 0.90 (t, 3H).
27. The use of other solid supports like Tenta-Gel resulted in detriment of yields and purities of the isolated compounds.