Splicing of constitutive upstream introns is essential for the recognition of intra-exonic suboptimal splice sites in the thrombopoietin gene

Nucleic Acids Research

Volumn 29, Issue 4, 2001, Pages 886-894

  Romano, Maurizio ^a,b   Marcucci, Roberto ^a   Baralle, Francisco E ^a  

^a INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Italy)

^b UNIVERSITY OF TRIESTE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; MESSENGER RNA; RNA; THROMBOPOIETIN;

ALTERNATIVE RNA SPLICING; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; EXON; GENE CONSTRUCT; GENE SEQUENCE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INTRON; LIVER CELL CARCINOMA; MOLECULAR RECOGNITION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RNA TRANSCRIPTION; SPLICEOSOME;

EID: 0035865835     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/29.4.886     Document Type: Article

References (39)

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4. Donor and acceptor splice signals within an exon of the human fibronectin gene: A new type of differential splicing
5. Primary structure of human fibronectin: Differential splicing may generate at least 10 polypeptides from a single gene
6. Cell-type-specific expression of alternatively spliced human fibronectin IIICS mRNAs
7. Regulation of alternative splicing in the IIICS region of human fibronectin pre-mRNA encoding cell binding sites CS1 and CS5
8. The mammalian homolog of suppressor-of-white-apricot regulates alternative mRNA splicing of CD45 exon 4 and fibronectin IIICS
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13. The role of exon sequences in splice site selection
14. The cardiac troponin T alternative exon contains a novel purine-rich positive splicing element
15. A splicing enhancer in the human fibronectin alternate ED1 exon interacts with SR proteins and stimulates U2 snRNP binding
16. A splicing enhancer exhibits both constitutive and regulated activities
17. A short sequence within two purine-rich enhancers determines 5′ splice site specificity
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19. Alternative conformations of the ColE1 replication primer modulate its interaction with RNA I
20. A secondary structure at the 3′ splice site affects the in vitro splicing reaction of mouse immunoglobulin mu chain pre-mRNAs
21. RNA secondary structure repression of a muscle-specific exon in HeLa cell nuclear extracts
22. Nonsense mutations inhibit splicing of MVM RNA in cis when they interrupt the reading frame of either exon of the final spliced product
23. Enhanced splicing of the first intron from the gonadotropin-releasing hormone (GnRH) primary transcript is a prerequisite for mature GnRH messenger RNA: Presence of GnRH neuron-specific splicing factors
24. A downstream splicing enhancer is essential for in vitro pre-mRNA splicing
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27. Statistical features of human exons and their flanking regions
28. A minimal intron length but no specific internal sequence is required for splicing the large rabbit beta-globin intron
29. Does steric interference between splice sites block the splicing of a short c-src neuron-specific exon in non-neuronal cells?
30. Selection of splice sites in pre-mRNAs with short internal exons
31. Splice site selection, rate of splicing and alternative splicing on nascent transcripts
32. Cotranscriptional splicing of a group I intron is facilitated by the Cbp2 protein
33. The human dystrophin gene requires 16 hours to be transcribed and is cotranscriptionally spliced
34. Splicing of Balbiani ring 1 gene pre-mRNA occurs simultaneously with transcription
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37. Co-transcriptional commitment to alternative splice site selection
38. Exon definition may facilitate splice site selection in RNAs with multiple exons
39. Large exon size does not limit splicing in vivo