In situ kinetic characterization of methylthioadenosine transport by the adenosine transporter (P2) of the African Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense

Biochemical Pharmacology

Volumn 61, Issue 4, 2001, Pages 449-457

  Goldberg, Burt ^a,b   Rattendi, Donna ^b   Lloyd, David ^d   Sufrin, Janice R ^e   Bacchi, Cyrus J ^b,c  

^a ST FRANCIS COLLEGE   (United States)

^b HASKINS LABORATORIES   (United States)

^c PACE UNIVERSITY   (United States)

^d UNIVERSITY OF WALES   (United Kingdom)

^e ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

African trypanosomes; Kinetic analysis; Methionine synthesis; Nucleoside transport

Indexed keywords

ADENOSINE; ADENOSINE DERIVATIVE; ADENOSINE TRANSPORTER; BUTYRIC ACID DERIVATIVE; CARRIER PROTEIN; INOSINE; KETOMETHYLTHIOBUTYRATE; METHIONINE; METHYLTHIOADENOSINE; S ADENOSYLMETHIONINE; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG DESIGN; NONHUMAN; NUCLEOSIDE TRANSPORT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN METABOLISM; STRAIN DIFFERENCE; TRANSPORT KINETICS; TRYPANOSOMA BRUCEI; TRYPANOSOMA RHODESIENSE;

ADENOSINE; ANIMALS; BINDING, COMPETITIVE; BIOLOGICAL TRANSPORT; CARRIER PROTEINS; KINETICS; MEMBRANE PROTEINS; METHIONINE; NUCLEOSIDE TRANSPORT PROTEINS; POLYAMINES; S-ADENOSYLHOMOCYSTEINE; THIONUCLEOSIDES; TRYPANOSOMA BRUCEI BRUCEI; TRYPANOSOMA BRUCEI RHODESIENSE;

EID: 0035865177     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(00)00560-8     Document Type: Article

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