Identification of active site residues in glucosylceramide synthase: A nucleotide-binding/catalytic motif conserved with processive β-glycosyltransferases

Journal of Biological Chemistry

Volumn 276, Issue 28, 2001, Pages 26492-26498

  Marks, David L ^b   Dominguez, Michel ^b   Wu, Kangjian ^b   Pagano, Richard E ^a  

^a MAYO CLINIC   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BACTERIA; BINDING ENERGY; BIOLOGICAL MEMBRANES; ENZYME INHIBITION; ENZYME KINETICS; LIPIDS; MUTAGENESIS;

GLYCOSYLATIONS;

BIOCHEMISTRY;

CELLULOSE; CERAMIDE GLUCOSYLTRANSFERASE; CHITIN; GLYCOSPHINGOLIPID; HYALURONIC ACID; N ETHYLMALEIMIDE; SYNTHETASE; GLUCOSYLTRANSFERASE; GLYCOSYLTRANSFERASE; RECOMBINANT PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; ENZYME ACTIVE SITE; ENZYME SUBSTRATE COMPLEX; GLYCOSYLATION; HYDROPHOBICITY; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; WESTERN BLOTTING; ANIMAL; BINDING SITE; CHEMISTRY; ENZYME ACTIVATION; ENZYME SPECIFICITY; GENETICS; METABOLISM; MOLECULAR GENETICS; RAT; SEQUENCE ALIGNMENT;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; ENZYME ACTIVATION; GLUCOSYLTRANSFERASES; GLYCOSYLTRANSFERASES; MOLECULAR SEQUENCE DATA; RATS; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY;

EID: 0035854736     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M102612200     Document Type: Article

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