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Volumn 20, Issue 5-6, 2001, Pages 771-788

Conversion of poorly immunogenic malaria repeat sequences into a highly immunogenic vaccine candidate

Author keywords

HBcAg; Malaria; Pre erythrocytic; Vaccine

Indexed keywords

CD4 ANTIGEN; EPITOPE; HEPATITIS B CORE ANTIGEN; HEPATITIS B CORE ANTIGEN CIRCUMSPOROOITE PROTEIN; IMMUNOGLOBULIN G; IMMUNOLOGICAL ADJUVANT; MALARIA VACCINE; MONOCLONAL ANTIBODY; RECOMBINANT ANTIGEN; UNCLASSIFIED DRUG; V12 PF3 1 ANTIGEN;

EID: 0035852348     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(01)00400-5     Document Type: Article
Times cited : (37)

References (71)
  • 6
    • 0016740645 scopus 로고
    • Immunization of man against falciparum and vivax malaria by use of attenuated sporozoites
    • (1975) Am J Trop Med Hyg , vol.24 , pp. 397-405
    • Clyde, D.F.1
  • 17
    • 18844463657 scopus 로고    scopus 로고
    • Improving protective immunity induced by DNA-based immunization: Priming with antigen and GM-CSF-encoding plasmid DNA and boosting with antigen-expressing recombinant poxvirus
    • (2000) J Immunol , vol.164 , pp. 5905-5912
    • Sedegah, M.1    Weiss, W.2    Sacci J.B., Jr.3
  • 23
    • 0029057169 scopus 로고
    • Safety, immunogenicity, and efficacy of a recombinantly produced Plasmodium falciparum circumsporozoite protein-hepatitis B surface antigen subunit vaccine
    • (1995) J Infect Dis , vol.171 , pp. 1576-1585
    • Gordon, D.M.1    McGovern, T.W.2    Krzych, U.3
  • 24
    • 0004170486 scopus 로고    scopus 로고
    • A preliminary evaluation of a recombinant circumsporozoite protein vaccine against Plasmodium falciparum malaria
    • RTS, S Malaria Vaccine Evaluation Group
    • (1997) N Engl J Med , vol.336 , pp. 86-91
    • Stoute, J.A.1    Slaoui, M.2    Heppner, G.3
  • 27
    • 0022996325 scopus 로고
    • The nucleocapsid of the hepatitis B virus is both a T-cell independent and a T-cell dependent antigen
    • (1986) Science , vol.234 , pp. 1398-1401
    • Milich, D.R.1    McLachlan, A.2
  • 39
    • 0000478940 scopus 로고
    • General method for the rapid solid-phase synthesis of large numbers of peptides: Specificity of antigen-antibody interaction at the level of individual amino acids
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 5131-5135
    • Houghten, R.A.1
  • 44
    • 0028136709 scopus 로고
    • A protease-sensitive hinge linking the two domains of the hepatitis B virus core protein is exposed on the viral capsid surface
    • (1994) J Virol , vol.68 , pp. 5548-5555
    • Seifer, M.1    Standring, D.N.2
  • 49
    • 0032053462 scopus 로고    scopus 로고
    • Plasmodium falciparum polyoximes: Highly immunogenic synthetic vaccines constructed by chemoselective ligation of repeat B-cell epitopes and a universal T-cell epitope of CS protein
    • (1998) Vaccine , vol.16 , pp. 590-600
    • Nardin, E.H.1    Calvo-Calle, J.M.2    Oliveira, G.A.3
  • 51
    • 0022513753 scopus 로고
    • Genetic control of the immune response in mice to a Plasmodium falciparum sporozoite vaccine: Widespread non-responsiveness to a single malaria T epitope in highly repetitive vaccine
    • (1986) J Exp Med , vol.164 , pp. 655-662
    • Good, M.F.1    Berzofsky, J.A.2    Maloy, W.L.3
  • 55
    • 0034979137 scopus 로고    scopus 로고
    • Molecular basis for the interaction of the hepatitis B virus core antigen with the surface immunoglobulin receptor on naïve B cells
    • (2001) J Virol , vol.75 , pp. 6367-6374
    • Lazdina, U.1    Cao, T.2    Steinbergs, J.3
  • 56
    • 0034984750 scopus 로고    scopus 로고
    • Hepatitis B virus core antigen binds and activates naïve human B cells in vivo: Studies with a human PBL-NOD/SCID mouse model
    • (2001) J Virol , vol.75 , pp. 6359-6366
    • Cao, T.1    Lazdina, U.2    Desombere, I.3
  • 60
    • 0021767981 scopus 로고
    • Possible role of immune responses to HBcAg in protection against hepatitis B infections
    • (1984) Lancet , vol.1 , pp. 172-178
    • Tabor, E.1    Gerety, R.J.2
  • 62
    • 0027171406 scopus 로고
    • + T cell clones obtained from Plasmodium falciparum sporozoite-immunized volunteers recognize polymorphic sequences of the circumsporozoite protein
    • (1993) J Immunol , vol.151 , pp. 489-499
    • Moreno, A.1    Clavijo, P.2    Edelman, R.3
  • 63
    • 0032745349 scopus 로고    scopus 로고
    • Potent induction of focused Th1-type cellular and humoral immune responses by RTS,S/SBAS2, a recombinant Plasmodium falciparum malaria vaccine
    • (1999) J Infect Dis , vol.180 , pp. 1656-1664
    • Lalvani, A.1    Moris, P.2    Voss, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.