Selective immunolesioning of cholinergic neurons in nucleus basalis magnocellularis impairs prepulse inhibition of acoustic startle

Neuroscience

Volumn 108, Issue 2, 2001, Pages 299-305

  Ballmaier, M ^a   Casamenti, F ^b   Zoli, M ^c   Pepeu, G ^b   Spano, P ^a  

^a UNIVERSITY OF BRESCIA   (Italy)

^b UNIVERSITY OF FLORENCE   (Italy)

^c UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

Author keywords

Cholinergic basal forebrain; Immunotoxin; Schizophrenia; Sensorimotor gating

Indexed keywords

SAPORIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR; CELL FUNCTION; CELL LOSS; CHANNEL GATING; CHOLINERGIC NERVE CELL; CONTROLLED STUDY; DIFFUSION; FOREBRAIN; MALE; NERVE CELL LESION; NONHUMAN; OLIVARY NUCLEUS; PREPULSE INHIBITION; PRIORITY JOURNAL; RAT; SCHIZOPHRENIA; SENSORIMOTOR FUNCTION; STARTLE REFLEX;

ACETYLCHOLINE; ANIMALS; ANTIBODIES, MONOCLONAL; BASAL NUCLEUS OF MEYNERT; BEHAVIOR, ANIMAL; CEREBRAL CORTEX; CHOLINE O-ACETYLTRANSFERASE; CHOLINERGIC AGENTS; CHOLINERGIC FIBERS; IMMUNOHISTOCHEMISTRY; IMMUNOTOXINS; MALE; N-GLYCOSYL HYDROLASES; NERVE DEGENERATION; NEURAL INHIBITION; NEURAL PATHWAYS; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; SCHIZOPHRENIA; STARTLE REACTION;

EID: 0035842586     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(01)00413-4     Document Type: Article

References (51)

1. Parallel organization of functionally segregated circuits linking basal ganglia and cortex
2. New perspectives in basal forebrain organization of special relevance for neuropsychiatric disorders: The striatopallidal, amygdaloid, and corticopetal components of substantia innominata
3. Loss of neurons in the nucleus basalis of Meynert in Alzheimer disease
4. Aniracetam restores object recognition impaired by age, scopolamine and nucleus basalis lesions
5. The cholinergic hypothesis of geriatric memory dysfunction
6. Differential effects on spatial navigation of immunotoxin-induced cholinergic lesions of the medial septal area and nucleus basalis magnocellularis
7. Cholinergic projections from the basal forebrain to frontal, temporal, occipital and cingulate cortices: A combined fluorescent and acetylcholinesterase analysis
8. Excitotoxic lesions of rat basal forebrain: Differential effects on choline acetyltransferase in the cortex and in the amygdala
9. Psychophysiological and information-processing approaches to schizophrenia
10. Removal of cholinergic input to rat posterior parietal cortex disrupts incremental processing of conditioned stimuli
11. Interactions between glutamatergic and monoaminergic systems within the basal ganglia - Implications for schizophrenia and Parkinson's disease
12. Basal forebrain cholinergic lesions disrupt increments but not decrements in conditioned stimulus processing
13. Selective removal of cholinergic neurons in basal forebrain alters cued target detection in rats
14. Cholinergic function and intellectual decline in Alzheimer's disease
15. Apomorphine disrupts the inhibition of acoustic startle induced by weak prepulses in rats
16. Mnemonic coding of visual space in the monkey's dorsolateral prefrontal cortex
17. Startle habituation and sensorimotor gating in schizophrenia and related animal models
18. Multiple transmitters modulate prepulse inhibition of startle: Relevance to schizophrenia
19. Sustained visual attention performance-associated prefrontal neuronal activity: Evidence for cholinergic modulation
20. Gating of information flow within the limbic system and the pathophysiology of schizophrenia
21. The anatomical relationship of the prefrontal cortex with the striatopallidal system, the thalamus and the amygdala: Evidence for a parallel organization
22. Basal forebrain in the context of schizophrenia
23. 'Perestroika' in the basal forebrain: Opening the border between neurology and psychiatry
24. Neuromorphological background of pathochemical studies in major psychoses
25. The organization of the basal ganglia-thalamocortical circuits: Open interconnected rather than closed segregated
26. Cortical map reorganization enabled by nucleus basalis activity
27. Lewy-body dementia and responsiveness to cholinesterase inhibitors: A paradigm for heterogeneity of Alzheimer's disease?
28. Effects of sustained cocaine exposure on sensorimotor gating of startle in rats
29. The role of cholinergic afferent projections in cognition: Impact of selective immunotoxins
30. Disorders of attention and perception in schizophrenia
31. Efficacy of rivastigmine in dementia with Lewy bodies: A randomised, double-blind, placebo-controlled international study
32. Frontal-striatal cognitive deficits in patients with chronic schizophrenia
33. Intraparenchimal infusions of 192 IgG-saporin: Development of a method for selective and discrete lesioning of cholinergic basal forebrain nuclei
34. The case for frontostriatal dysfunction in schizophrenia
35. Schizophrenia
36. Abnormal regulation of corticopetal cholinergic neurons and impaired information processing in neuropsychiatric disorders
37. Brain inflammatory reaction in an animal model of neuronal degeneration and its modulation by an anti-inflammatory drug: Implication in Alzheimer's disease
38. Lesions of the nucleus basalis magnocellularis do not impair prepulse inhibition and latent inhibition of fear-potentiated startle in the rat
39. Parallel activation of thalamic and cortical neurons by brainstem and basal forebrain cholinergic systems
40. Cholinergic and non-cholinergic neurons of cat basal forebrain project to reticular and mediodorsal thalamic nuclei
41. An anatomy of schizophrenia?
42. Prepulse inhibition of acoustic startle in rats after lesions of the peduncolopontine tegmental nucleus
43. Using an animal model of deficient sensorimotor gating to study the pathophysiology and new treatments in schizophrenia
44. Dopamine, schizophrenia, mania and depression: Toward a unified hypothesis of cortico-striato-pallido-thalamic function
45. Toward understanding the biology of a complex phenotype: Rat strain and substrain differences in the sensorimotor gating-disruptive effects of dopamine agonists
46. Alz-50 immunoreactivity in the thalamic reticular nucleus in Alzheimer's disease
47. Ascending cholinergic pathways in the rat brain
48. Evidence for dysfunction of a prefrontal-limbic network in schizophrenia: An MRI and rCBF study of discordant monozygotic twins
49. Schizophrenia and Alzheimer's disease: Clinical and pathophysiologic analogies
50. Alzheimer's disease and senile dementia: Loss of neurons in the basal forebrain