Synthesis of constrained L-phenylalanine derivatives incorporating a benzazepinone or an azepinone ring as VCAM/VLA-4 antagonists

Tetrahedron Letters

Volumn 42, Issue 50, 2001, Pages 8757-8760

  Sidduri, Achyutharao ^a   Lou, Jian Ping ^a   Campbell, Robert ^a   Rowan, Karen ^a   Tilley, Jefferson W ^a  

^a HOFFMANN LA ROCHE INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZEPINE DERIVATIVE; AZEPINONE; BENZAZEPINE DERIVATIVE; BENZAZEPINONE; BETA1 INTEGRIN; BLOCKING AGENT; DRUG ANALOG; PHENYLALANINE DERIVATIVE; PROTEIN; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE; VASCULAR CELL ADHESION MOLECULE ANTAGONIST; VERY LATE ACTIVATION ANTIGEN 4 ANTAGONIST;

ARTICLE; CATALYSIS; COMPARATIVE STUDY; CYCLIZATION; DRUG CONFORMATION; DRUG POTENCY; DRUG SYNTHESIS; ENZYME LINKED IMMUNOSORBENT ASSAY;

EID: 0035842103     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(01)01926-8     Document Type: Article

References (7)