Adapting pharmacokinetic properties of a humanized anti-interleukin-8 antibody for therapeutic applications using site-specific pegylation

Cytokine

Volumn 16, Issue 3, 2001, Pages 106-119

  Leong, Steven R ^a   DeForge, Laura ^a   Presta, Leonard ^a   Gonzalez, Tania ^a   Fan, Audrey ^a   Reichert, Marcel ^a   Chuntharapai, Anan ^a   Jin Kim, K ^a   Tumas, Daniel B ^a   Lee, Wyne Pun ^a   Gribling, Peter ^a   Snedecor, Brad ^a   Chen, Han ^a   Hsei, Vanessa ^a   Schoenhoff, Monika ^a   Hale, Victoria ^a   Deveney, James ^a   Koumenis, Iphigenia ^a   Shahrokh, Zahra ^a   McKay, Patrick ^a   Galan, Walter ^a   Wagner, Brian ^a   Narindray, Daljit ^a   Hébert, Caroline ^a   Zapata, Gerardo ^a   more..

^a GENENTECH INC   (United States)

Author keywords

Differentiation; DNA shuffling; Heterodimer formation; Interleukin 12; Product homogeneity; Proliferation

Indexed keywords

ALANINE; CYTOKINE ANTIBODY; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN G; INTERLEUKIN 8; INTERLEUKIN 8 ANTIBODY; MACROGOL; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY AFFINITY; ANTIGEN BINDING; ARTICLE; BACTERIOPHAGE; CONTROLLED STUDY; DISEASE MODEL; DRUG EFFICACY; DRUG HALF LIFE; ESCHERICHIA COLI; IN VIVO STUDY; ISCHEMIA; MALE; MOLECULAR CLONING; MUTAGENESIS; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; RABBIT; REPERFUSION INJURY;

ESCHERICHIA COLI; ORYCTOLAGUS CUNICULUS;

EID: 0035824187     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1006/cyto.2001.0936     Document Type: Article

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