-
1
-
-
0029995670
-
Thiazolidinediones in the treatment of insulin resistance and type ?diabetes
-
Saltiel AR, Olefsky JM: Thiazolidinediones in the treatment of insulin resistance and type ?diabetes. Diabetes 1996;45:1661-1669.
-
(1996)
Diabetes
, vol.45
, pp. 1661-1669
-
-
Saltiel, A.R.1
Olefsky, J.M.2
-
2
-
-
0031898610
-
PPARγ: Adipogenic regulator and thiazolidinedione receptor
-
Spiegelman BM: PPARγ: Adipogenic regulator and thiazolidinedione receptor. Diabetes 1998; 47:507-514.
-
(1998)
Diabetes
, vol.47
, pp. 507-514
-
-
Spiegelman, B.M.1
-
3
-
-
0029016829
-
An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ (PPARγ)
-
Lehmann JM, Moore LB, Smith-Oliver D, Wilkinson WM, Wilson TM, Kliewer SA: An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ (PPARγ). J Biol Chem 1995;270: 12953-12956.
-
(1995)
J Biol Chem
, vol.270
, pp. 12953-12956
-
-
Lehmann, J.M.1
Moore, L.B.2
Smith-Oliver, D.3
Wilkinson, W.M.4
Wilson, T.M.5
Kliewer, S.A.6
-
4
-
-
0030062325
-
The structure-activity relationship between peroxisome-activated receptor γ agonism and the antihyperglycemic activity of thiazolidinediones
-
Wilson TM, Cobb JE, Cowan DJ, Wiethe RW, Correa ID, Prakash SR, Beck KD, Moore LB, Kliewer SA, Lehmann JM: The structure-activity relationship between peroxisome-activated receptor γ agonism and the antihyperglycemic activity of thiazolidinediones. J Med Chem 1996;39:665-668.
-
(1996)
J Med Chem
, vol.39
, pp. 665-668
-
-
Wilson, T.M.1
Cobb, J.E.2
Cowan, D.J.3
Wiethe, R.W.4
Correa, I.D.5
Prakash, S.R.6
Beck, K.D.7
Moore, L.B.8
Kliewer, S.A.9
Lehmann, J.M.10
-
5
-
-
0028641559
-
Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor
-
Tontonoz P, Hu E, Spiegelman BM: Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor. Cell 1994;79:1147-1156.
-
(1994)
Cell
, vol.79
, pp. 1147-1156
-
-
Tontonoz, P.1
Hu, E.2
Spiegelman, B.M.3
-
6
-
-
0030835678
-
The organization, promoter analysis, and expression of the human PPARγ gene
-
Fajas L, Auboeu D, Raspe E, Schoonjans K, Lefebvre A-M, Saladin R, Najib J, Laville M, Fruchart J-C, Deeb S, Vidal-Puig A, Flier J, Briggs MR, Staels B, Vidal H, Auwerx J: The organization, promoter analysis, and expression of the human PPARγ gene. J Biol Chem 1997;272:18779-18789.
-
(1997)
J Biol Chem
, vol.272
, pp. 18779-18789
-
-
Fajas, L.1
Auboeu, D.2
Raspe, E.3
Schoonjans, K.4
Lefebvre, A.-M.5
Saladin, R.6
Najib, J.7
Laville, M.8
Fruchart, J.-C.9
Deeb, S.10
Vidal-Puig, A.11
Flier, J.12
Briggs, M.R.13
Staels, B.14
Vidal, H.15
Auwerx, J.16
-
7
-
-
0030047806
-
Differential expression of peroxisome proliferator-activated receptors (PPARs): Tissue distribution of PPAR-α, -β, and -γ in the adult rat
-
Braissant O, Foufelle F, Scotto C, Dauça M, Wahli W: Differential expression of peroxisome proliferator-activated receptors (PPARs): Tissue distribution of PPAR-α, -β, and -γ in the adult rat. Endocrinology 1996;137:354-366.
-
(1996)
Endocrinology
, vol.137
, pp. 354-366
-
-
Braissant, O.1
Foufelle, F.2
Scotto, C.3
Dauça, M.4
Wahli, W.5
-
8
-
-
0029152375
-
Isolation of the human peroxisome proliferator activated receptor gamma cDNA: Expression in hematopoietic cells and chromosomal mapping
-
Greene ME, Blumberg B, Mcbride OW, Yi HF, Kronquist K, Kwan K, Hsieh L, Greene G, Nimer D: Isolation of the human peroxisome proliferator activated receptor gamma cDNA: Expression in hematopoietic cells and chromosomal mapping. Gene Expr 1995;4:281-299.
-
(1995)
Gene Expr
, vol.4
, pp. 281-299
-
-
Greene, M.E.1
Blumberg, B.2
McBride, O.W.3
Yi, H.F.4
Kronquist, K.5
Kwan, K.6
Hsieh, L.7
Greene, G.8
Nimer, D.9
-
9
-
-
0029847076
-
Peroxisome proliferator-activated receptor-activation by thiazolidinediones induces adipogenesis in bone marrow stromal cells
-
Gimble JM, Robinson CE, Wu X, Kelly KA, Rodriguez BR, Kliewer SA, Lehmann JM, Morris DC: Peroxisome proliferator-activated receptor-activation by thiazolidinediones induces adipogenesis in bone marrow stromal cells. Mol Pharmacol 1996;50:1087-1094.
-
(1996)
Mol Pharmacol
, vol.50
, pp. 1087-1094
-
-
Gimble, J.M.1
Robinson, C.E.2
Wu, X.3
Kelly, K.A.4
Rodriguez, B.R.5
Kliewer, S.A.6
Lehmann, J.M.7
Morris, D.C.8
-
10
-
-
0002633987
-
Clinical evaluation of a new oral hypoglycemic drug Cs-045 in patients with non-insulin dependent diabetes mellitus poorly controlled by sulfonylureas. A double-blind, placebo-controlled study
-
Kosaka K, Kuzuya T, Akanuma H, Shigeta Y, Kaneko T: Clinical evaluation of a new oral hypoglycemic drug Cs-045 in patients with non-insulin dependent diabetes mellitus poorly controlled by sulfonylureas. A double-blind, placebo-controlled study. Rinsho Igaku 1993; 9(suppl):19-37.
-
(1993)
Rinsho Igaku
, vol.9
, Issue.SUPPL.
, pp. 19-37
-
-
Kosaka, K.1
Kuzuya, T.2
Akanuma, H.3
Shigeta, Y.4
Kaneko, T.5
-
11
-
-
0343940590
-
Continuous growth and differentiation of human myeloid leukemic cells in suspension culture
-
Collins SJ, Gallo RC, Gallagher RE: Continuous growth and differentiation of human myeloid leukemic cells in suspension culture. Nature 1977;70:1233-1244.
-
(1977)
Nature
, vol.70
, pp. 1233-1244
-
-
Collins, S.J.1
Gallo, R.C.2
Gallagher, R.E.3
-
12
-
-
0001679798
-
Induction of differentiation of the human promyelocytic leukemia cell line (HL60) by retinoic acid
-
Breitman TR, Selonick SE, Collins SJ: Induction of differentiation of the human promyelocytic leukemia cell line (HL60) by retinoic acid. Proc Natl Acad Sci USA 1980;77:2936-2940.
-
(1980)
Proc Natl Acad Sci USA
, vol.77
, pp. 2936-2940
-
-
Breitman, T.R.1
Selonick, S.E.2
Collins, S.J.3
-
13
-
-
0028577777
-
Increased resistance to apoptosis associated with HL60 myeloid differentiation status
-
McCarthy JV, Fernandes RS, Gotter TG: Increased resistance to apoptosis associated with HL60 myeloid differentiation status. Anticancer Res 1994;14:2063-2072.
-
(1994)
Anticancer Res
, vol.14
, pp. 2063-2072
-
-
McCarthy, J.V.1
Fernandes, R.S.2
Gotter, T.G.3
-
14
-
-
0028817069
-
Regulation and function of BCL-2 during differentiation-induced cell death in HL60 promyelocytic cells
-
Benito A, Grillot D, Nunez G, Fernandez-Luna JL: Regulation and function of BCL-2 during differentiation-induced cell death in HL60 promyelocytic cells. Am J Pathol 1995;146:481-490.
-
(1995)
Am J Pathol
, vol.146
, pp. 481-490
-
-
Benito, A.1
Grillot, D.2
Nunez, G.3
Fernandez-Luna, J.L.4
-
15
-
-
0342941158
-
Granulocytic differentiation of HL60 cells results in spontaneous apoptosis mediated by increased caspase expression
-
Watson RWG, Rotstein OD, Parodo J, Bitar R, Hackam D, Marshall JC: Granulocytic differentiation of HL60 cells results in spontaneous apoptosis mediated by increased caspase expression. FFBS Lett 1997;412:603-609.
-
(1997)
FFBS Lett
, vol.412
, pp. 603-609
-
-
Watson, R.W.G.1
Rotstein, O.D.2
Parodo, J.3
Bitar, R.4
Hackam, D.5
Marshall, J.C.6
-
16
-
-
0018771246
-
Induction of differentiation in human promyelocytic leukemia cells by tumor promoters
-
Rovera G, O'Brien TG, Diamond L: Induction of differentiation in human promyelocytic leukemia cells by tumor promoters. Science 1979; 204:868-870.
-
(1979)
Science
, vol.204
, pp. 868-870
-
-
Rovera, G.1
O'Brien, T.G.2
Diamond, L.3
-
17
-
-
0029097177
-
Design and synthesis of potent retinoid X receptor selective ligands that induce apoptosis in leukemia cells
-
Boehm MF, Zhang L, Zhi L, McClurg MR, Berger E, Wagoner M, Mais DE, Suto CM, Davies PJA, Heyman RA, Nadzan AM: Design and synthesis of potent retinoid X receptor selective ligands that induce apoptosis in leukemia cells. J Med Chem 1995;38:3146-3155.
-
(1995)
J Med Chem
, vol.38
, pp. 3146-3155
-
-
Boehm, M.F.1
Zhang, L.2
Zhi, L.3
McClurg, M.R.4
Berger, E.5
Wagoner, M.6
Mais, D.E.7
Suto, C.M.8
Davies, P.J.A.9
Heyman, R.A.10
Nadzan, A.M.11
-
18
-
-
0016738010
-
Rapid flow cytofluorometric analysis of mammallian cell cycle by propidium iodide staining
-
Kinsham A: Rapid flow cytofluorometric analysis of mammallian cell cycle by propidium iodide staining. J Cell Biol 1975;66:188-193.
-
(1975)
J Cell Biol
, vol.66
, pp. 188-193
-
-
Kinsham, A.1
-
19
-
-
0026492817
-
Features of apoptotic cells measured by flow cytometry
-
Darzynkiewicz Z, Brouno S, Del Bino G, Gorczyca W, Hotz MA, Lassota P, Tragonos F: Features of apoptotic cells measured by flow cytometry. Cytometry 1992;13:795-808.
-
(1992)
Cytometry
, vol.13
, pp. 795-808
-
-
Darzynkiewicz, Z.1
Brouno, S.2
Del Bino, G.3
Gorczyca, W.4
Hotz, M.A.5
Lassota, P.6
Tragonos, F.7
-
20
-
-
0023612470
-
Gene induction by γ-irradiation leads to DNA fragmentation in lymphocytes
-
Selins KS, Cohen JJ: Gene induction by γ-irradiation leads to DNA fragmentation in lymphocytes. J Immunol 1987;139:3199.
-
(1987)
J Immunol
, vol.139
, pp. 3199
-
-
Selins, K.S.1
Cohen, J.J.2
-
22
-
-
0030861641
-
Monocytic differentiation of HL60 promyelocytic leukemia cells correlates with the induction of Bcl-XL
-
Chatterjee D, Han Z, Mendoza J, Goodglick L, Hendrickson EA, Pantazis P, Wyche JH: Monocytic differentiation of HL60 promyelocytic leukemia cells correlates with the induction of Bcl-XL. Cell Growth Differ 1997;8: 1083-1089.
-
(1997)
Cell Growth Differ
, vol.8
, pp. 1083-1089
-
-
Chatterjee, D.1
Han, Z.2
Mendoza, J.3
Goodglick, L.4
Hendrickson, E.A.5
Pantazis, P.6
Wyche, J.H.7
-
23
-
-
0029089086
-
Potentiating effects of clofibric acid on the differentiation of HL60 human promyelocytic leukemia cells induced by retinoids
-
Nilsson A, Farrants AKO, Nesland JM, Finstad HS, Pederson JI: Potentiating effects of clofibric acid on the differentiation of HL60 human promyelocytic leukemia cells induced by retinoids. Eur J Cell Biol 1995;67:379-385.
-
(1995)
Eur J Cell Biol
, vol.67
, pp. 379-385
-
-
Nilsson, A.1
Farrants, A.K.O.2
Nesland, J.M.3
Finstad, H.S.4
Pederson, J.I.5
-
24
-
-
17444442152
-
Sensitization of diabetic and obese mice to insulin by retinoid X receptor agonists
-
Mukherjee R, Davies PJA, Crombie DL, Bischoff ED, Casario RM, Jow L, Hamann LG, Boehm MF, Mondon CE, Nadzan AM, Paterniti JR Jr, Heyman RA: Sensitization of diabetic and obese mice to insulin by retinoid X receptor agonists. Nature 1997;386:407-410.
-
(1997)
Nature
, vol.386
, pp. 407-410
-
-
Mukherjee, R.1
Davies, P.J.A.2
Crombie, D.L.3
Bischoff, E.D.4
Casario, R.M.5
Jow, L.6
Hamann, L.G.7
Boehm, M.F.8
Mondon, C.E.9
Nadzan, A.M.10
Paterniti J.R., Jr.11
Heyman, R.A.12
-
25
-
-
12644265334
-
Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator activated receptor y and retinoid X receptor
-
Tontonoz P, Singer S, Forman BM, Sarraf P, Fletcher JA, Fletcher CDM, Brun RP, Mueller E, Altios S, Oppenheim H, Evans RM, Spiegelman BM: Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator activated receptor y and retinoid X receptor. Proc Natl Acad Sci USA 1997;94:237-241.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 237-241
-
-
Tontonoz, P.1
Singer, S.2
Forman, B.M.3
Sarraf, P.4
Fletcher, J.A.5
Fletcher, C.D.M.6
Brun, R.P.7
Mueller, E.8
Altios, S.9
Oppenheim, H.10
Evans, R.M.11
Spiegelman, B.M.12
-
26
-
-
0031557687
-
Action mechanism of retinoid-synergistic dibenzodiazepines
-
Umemiya H, Kagechika H, Fukasawa H, Kawachi E, Ebisawa M, Hashimoto Y, Eisenmann G, Erb C, Pornon A, Chambon P, Gronemeyer H, Shudo K: Action mechanism of retinoid-synergistic dibenzodiazepines. Biochem Biophys Res Commun 1997;233:121-125.
-
(1997)
Biochem Biophys Res Commun
, vol.233
, pp. 121-125
-
-
Umemiya, H.1
Kagechika, H.2
Fukasawa, H.3
Kawachi, E.4
Ebisawa, M.5
Hashimoto, Y.6
Eisenmann, G.7
Erb, C.8
Pornon, A.9
Chambon, P.10
Gronemeyer, H.11
Shudo, K.12
-
27
-
-
0031050617
-
3,5,3'-Triiodo-L-thyronine potentiates all-trans-retinoic acid-induced apoptosis during differentiation of the promyeloleukemic cell HL60
-
Suzuki S, Kobayashi H, Sekine R, Kumagai M, Mikoshiba M, Mori J, Hara M, Ichikawa K, Hashizume K: 3,5,3'-Triiodo-L-thyronine potentiates all-trans-retinoic acid-induced apoptosis during differentiation of the promyeloleukemic cell HL60. Endocrinology 1997;138: 805-809.
-
(1997)
Endocrinology
, vol.138
, pp. 805-809
-
-
Suzuki, S.1
Kobayashi, H.2
Sekine, R.3
Kumagai, M.4
Mikoshiba, M.5
Mori, J.6
Hara, M.7
Ichikawa, K.8
Hashizume, K.9
-
28
-
-
0032540012
-
PPARγ promotes monocyte/macrophage differentiation and uptake of oxidized LDL
-
Tontonoz P, Nagy L, Alvarez JGA, Thomazy VA, Evans RM: PPARγ promotes monocyte/macrophage differentiation and uptake of oxidized LDL. Cell 1998;93:241-252.
-
(1998)
Cell
, vol.93
, pp. 241-252
-
-
Tontonoz, P.1
Nagy, L.2
Alvarez, J.G.A.3
Thomazy, V.A.4
Evans, R.M.5
-
29
-
-
0025784539
-
Wild-type p53 induces apoptosis of myeloid leukemic cells that is inhibited by interleukin-6
-
Yonish-Rouach E, Resnitzky D, Lotem J, Sachs L, Kimchi A, Oren M: Wild-type p53 induces apoptosis of myeloid leukemic cells that is inhibited by interleukin-6. Nature 1991; 352:345-347.
-
(1991)
Nature
, vol.352
, pp. 345-347
-
-
Yonish-Rouach, E.1
Resnitzky, D.2
Lotem, J.3
Sachs, L.4
Kimchi, A.5
Oren, M.6
-
30
-
-
0027258466
-
Thymocyte apoptosis induced by p53-dependent and independent pathways
-
Clarke AR, Purdie CA, Harrison DF, Morris RG, Bird CC, Hooper ML, Wyllie AH: Thymocyte apoptosis induced by p53-dependent and independent pathways. Nature 1993;362:849-852.
-
(1993)
Nature
, vol.362
, pp. 849-852
-
-
Clarke, A.R.1
Purdie, C.A.2
Harrison, D.F.3
Morris, R.G.4
Bird, C.C.5
Hooper, M.L.6
Wyllie, A.H.7
-
31
-
-
0001606206
-
Major deletions in the gene coding the p53 tumor antigen cause lack of p53 expression in HL60 cells
-
Wolf D, Rotter V: Major deletions in the gene coding the p53 tumor antigen cause lack of p53 expression in HL60 cells. Proc Natl Acd Sci USA 1985;82:790-794.
-
(1985)
Proc Natl Acd Sci USA
, vol.82
, pp. 790-794
-
-
Wolf, D.1
Rotter, V.2
-
32
-
-
0029026548
-
FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis
-
Chinnaiyan AM, O'Rourke K, Tewari M, Dixit VM: FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis. Cell 1995;81:505-512.
-
(1995)
Cell
, vol.81
, pp. 505-512
-
-
Chinnaiyan, A.M.1
O'Rourke, K.2
Tewari, M.3
Dixit, V.M.4
-
33
-
-
0030255449
-
Mechanisms of Bcl-2 family protein function and dysfunction in health and disease
-
Reed JC: Mechanisms of Bcl-2 family protein function and dysfunction in health and disease. Behring Inst Mitt 1996;97:72-100.
-
(1996)
Behring Inst Mitt
, vol.97
, pp. 72-100
-
-
Reed, J.C.1
-
34
-
-
0031007772
-
The expression of bcl-X is down-regulated during differentiation of human hematopoietic progenitor cells along the granulocyte but not the monocyte/macrophage lineage
-
Sanz C, Benito A, Silva M, Albella B, Richard C, Segovia JC, Insunza A, Buerren JA, Fernandez-Luna JL: The expression of bcl-X is down-regulated during differentiation of human hematopoietic progenitor cells along the granulocyte but not the monocyte/macrophage lineage. Blood 1997;89:3199-3204.
-
(1997)
Blood
, vol.89
, pp. 3199-3204
-
-
Sanz, C.1
Benito, A.2
Silva, M.3
Albella, B.4
Richard, C.5
Segovia, J.C.6
Insunza, A.7
Buerren, J.A.8
Fernandez-Luna, J.L.9
-
35
-
-
0027166048
-
Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
-
Oltval Z, Millman CL, Korsmeyer SJ: Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 1993;74:609-619.
-
(1993)
Cell
, vol.74
, pp. 609-619
-
-
Oltval, Z.1
Millman, C.L.2
Korsmeyer, S.J.3
-
36
-
-
0028809209
-
Bad, a heterodimeric partner for Bcl-XL and Bcl-2 displaces bax and promotes cell death
-
Yang E, Zha J, Jockel J, Boise LH, Thompson CB, Korsmeyer SJ: Bad, a heterodimeric partner for Bcl-XL and Bcl-2 displaces Bax and promotes cell death. Cell 1995;80:285-291.
-
(1995)
Cell
, vol.80
, pp. 285-291
-
-
Yang, E.1
Zha, J.2
Jockel, J.3
Boise, L.H.4
Thompson, C.B.5
Korsmeyer, S.J.6
|