ph gradients in immobilized amidases and their influence on rates and yields of β-lactam hydrolysis

Biotechnology and Bioengineering

Volumn 62, Issue 3, 1999, Pages 267-277

  Spiess A ^a   Schlothauer, R C ^a,b   Hinrichs, J ^a   Scheidat, B ^a   Kasche, V ^a  

^a HAMBURG UNIVERSITY OF TECHNOLOGY   (Germany)

^b NEW ZEALAND DAIRY RESEARCH INSTITUTE   (New Zealand)

Author keywords

Glutaryl amidase; Hydrolysis; Penicillin amidase; PH gradients; Reactor design

Indexed keywords

ANTIBIOTICS; BIOCONVERSION; BIOREACTORS; BOUNDARY LAYERS; COMPUTATIONAL METHODS; DIFFERENTIAL EQUATIONS; HYDROLYSIS; MASS TRANSFER; MATHEMATICAL MODELS; ORGANIC ACIDS; PH EFFECTS; REACTION KINETICS;

FLUORIMETRY; GLUTARYLAMINOCEPHALOSPORANIC ACID; PENICILLIN AMIDASE; TRANSPORT REACTION DIFFERENTIAL EQUATION;

ENZYME IMMOBILIZATION;

7 AMINOCEPHALOSPORANIC ACID; AMIDASE; BETA LACTAM ANTIBIOTIC; PENICILLIN G;

ARTICLE; DRUG HYDROLYSIS; ENZYME IMMOBILIZATION; ENZYME KINETICS; ENZYME STABILITY; EQUILIBRIUM CONSTANT; FLUORESCENCE; PH; REACTION TIME; REACTOR;

AMIDOHYDROLASES; ANTI-BACTERIAL AGENTS; CEPHALOSPORINS; FLUORESCEIN-5-ISOTHIOCYANATE; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; KINETICS; MODELS, THEORETICAL; PENICILLIN G; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, FLUORESCENCE; TEMPERATURE;

EID: 0009577545     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0290(19990205)62:3<267::AID-BIT3>3.0.CO;2-K     Document Type: Article

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