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Volumn 243, Issue 1-2, 2000, Pages 75-83

Genomic organization and transcriptional analysis of the human genes coding for caveolin-1 and caveolin-2

Author keywords

Caveolae; Cholesterol homeostasis; Sterol responsive element; Tumor suppressor

Indexed keywords

CAVEOLIN; CAVEOLIN 1; CAVEOLIN 2; CHOLESTEROL; UNCLASSIFIED DRUG;

EID: 0033975048     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(99)00559-4     Document Type: Article
Times cited : (28)

References (31)
  • 1
    • 0031692336 scopus 로고    scopus 로고
    • The caveolae membrane system
    • Anderson R.G. The caveolae membrane system. Annu. Rev. Biochem. 67:1998;199-225.
    • (1998) Annu. Rev. Biochem. , vol.67 , pp. 199-225
    • Anderson, R.G.1
  • 2
    • 0030982565 scopus 로고    scopus 로고
    • Two sterol regulatory element-like sequences mediate up-regulation of caveolin gene transcription in response to low density lipoprotein free cholesterol
    • 693-10 698
    • Bist A., Fielding P.E., Fielding C.J. Two sterol regulatory element-like sequences mediate up-regulation of caveolin gene transcription in response to low density lipoprotein free cholesterol. Proc. Natl. Acad. Sci. USA. 94:1997;10 693-10 698.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 10
    • Bist, A.1    Fielding, P.E.2    Fielding, C.J.3
  • 4
    • 0030960332 scopus 로고    scopus 로고
    • Recombinant expression of caveolin-1 in oncogenically transformed cells abrogates anchorage-independent growth
    • 374-16 381
    • Engelman J.A., Wykoff C.C., Yasuhara S., Song K.S., Okamoto T., Lisanti M.P. Recombinant expression of caveolin-1 in oncogenically transformed cells abrogates anchorage-independent growth. J. Biol. Chem. 272:1997;16 374-16 381.
    • (1997) J. Biol. Chem. , vol.272 , pp. 16
    • Engelman, J.A.1    Wykoff, C.C.2    Yasuhara, S.3    Song, K.S.4    Okamoto, T.5    Lisanti, M.P.6
  • 5
    • 0344222158 scopus 로고    scopus 로고
    • Chromosomal localization, genomic organization, and developmental expression of the murine caveolin gene family (Cav-1, -2, and -3). Cav-1 and Cav-2 genes map to a known tumor suppressor locus (6-A2/7q31)
    • Engelman J.A., Zhang X.L., Galbiati F., Lisanti M.P. Chromosomal localization, genomic organization, and developmental expression of the murine caveolin gene family (Cav-1, -2, and -3). Cav-1 and Cav-2 genes map to a known tumor suppressor locus (6-A2/7q31). FEBS Lett. 429:1998;330-336.
    • (1998) FEBS Lett. , vol.429 , pp. 330-336
    • Engelman, J.A.1    Zhang, X.L.2    Galbiati, F.3    Lisanti, M.P.4
  • 6
    • 0031758918 scopus 로고    scopus 로고
    • Genes encoding human caveolin-1 and -2 are co-localized to the D7s522 locus (7q31.1), a known fragile site (Fra7g) that is frequently deleted in human cancers
    • Engelman J.A., Zhang X.L., Lisanti M.P. Genes encoding human caveolin-1 and -2 are co-localized to the D7s522 locus (7q31.1), a known fragile site (Fra7g) that is frequently deleted in human cancers. FEBS Lett. 436:1998;403-410.
    • (1998) FEBS Lett. , vol.436 , pp. 403-410
    • Engelman, J.A.1    Zhang, X.L.2    Lisanti, M.P.3
  • 7
    • 0032951245 scopus 로고    scopus 로고
    • Sequence and detailed organization of the human caveolin-1 and -2 genes located near the D7S522 locus (7q31.1). Methylation of a CpG island in the 5′ promoter region of the caveolin-1 gene in human breast cancer cell lines
    • Engelman J.A., Zhang X.L., Lisanti M.P. Sequence and detailed organization of the human caveolin-1 and -2 genes located near the D7S522 locus (7q31.1). Methylation of a CpG island in the 5′ promoter region of the caveolin-1 gene in human breast cancer cell lines. FEBS Lett. 448:1999;221-230.
    • (1999) FEBS Lett. , vol.448 , pp. 221-230
    • Engelman, J.A.1    Zhang, X.L.2    Lisanti, M.P.3
  • 8
    • 0030809601 scopus 로고    scopus 로고
    • Intracellular cholesterol transport
    • Fielding C.J., Fielding P.E. Intracellular cholesterol transport. J. Lipid Res. 38:1997;1503-1521.
    • (1997) J. Lipid Res. , vol.38 , pp. 1503-1521
    • Fielding, C.J.1    Fielding, P.E.2
  • 9
    • 0030970279 scopus 로고    scopus 로고
    • Caveolin mRNA levels are up-regulated by free cholesterol and down-regulated by oxysterols in fibroblast monolayers
    • Fielding C.J., Bist A., Fielding P.E. Caveolin mRNA levels are up-regulated by free cholesterol and down-regulated by oxysterols in fibroblast monolayers. Proc. Natl. Acad. Sci. USA. 94:1997;3753-3758.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 3753-3758
    • Fielding, C.J.1    Bist, A.2    Fielding, P.E.3
  • 10
    • 0029086362 scopus 로고
    • De novo formation of caveolae in lymphocytes by expression of VIP21-caveolin
    • Fra A.M., Williamson E., Simons K., Parton R.G. De novo formation of caveolae in lymphocytes by expression of VIP21-caveolin. Proc. Natl. Acad. Sci. USA. 92:1995;8655-8659.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 8655-8659
    • Fra, A.M.1    Williamson, E.2    Simons, K.3    Parton, R.G.4
  • 11
    • 0033559101 scopus 로고    scopus 로고
    • Human caveolin-1 and caveolin-2 are closely linked genes colocalized with WI-5336 in a region of 7q31 frequently deleted in tumors
    • Fra A.M., Mastroianni N., Mancini M., Pasqualetto E., Sitia R. Human caveolin-1 and caveolin-2 are closely linked genes colocalized with WI-5336 in a region of 7q31 frequently deleted in tumors. Genomics. 56:1999;355-356.
    • (1999) Genomics , vol.56 , pp. 355-356
    • Fra, A.M.1    Mastroianni, N.2    Mancini, M.3    Pasqualetto, E.4    Sitia, R.5
  • 12
    • 0032538790 scopus 로고    scopus 로고
    • Targeted downregulation of caveolin-1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAP kinase cascade
    • Galbiati F., Volonte D., Engelman J.A., Watanabe G., Burk R., Pestell R.G., Lisanti M.P. Targeted downregulation of caveolin-1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAP kinase cascade. EMBO J. 17:1998;6633-6648.
    • (1998) EMBO J. , vol.17 , pp. 6633-6648
    • Galbiati, F.1    Volonte, D.2    Engelman, J.A.3    Watanabe, G.4    Burk, R.5    Pestell, R.G.6    Lisanti, M.P.7
  • 13
    • 0031888035 scopus 로고    scopus 로고
    • Regulation of caveolin and caveolae by cholesterol in MDCK cells
    • Hailstones D., Sleer L.S., Parton R.G., Stanley K.K. Regulation of caveolin and caveolae by cholesterol in MDCK cells. J. Lipid Res. 39:1998;369-379.
    • (1998) J. Lipid Res. , vol.39 , pp. 369-379
    • Hailstones, D.1    Sleer, L.S.2    Parton, R.G.3    Stanley, K.K.4
  • 16
    • 0028953271 scopus 로고
    • Reduction of caveolin and caveolae in oncogenically transformed cells
    • Koleske A.J., Baltimore D., Lisanti M.P. Reduction of caveolin and caveolae in oncogenically transformed cells. Proc. Natl. Acad. Sci. USA. 92:1995;1381-1385.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 1381-1385
    • Koleske, A.J.1    Baltimore, D.2    Lisanti, M.P.3
  • 17
    • 0029963491 scopus 로고    scopus 로고
    • Detailed deletion mapping with a refined physical map of 7q31 localizes a putative tumor suppressor gene for breast cancer in the region of MET
    • Lin J.C., Scherer S.W., Tougas L., Traverso G., Tsui L.C., Andrulis I.L., Jothy S., Park M. Detailed deletion mapping with a refined physical map of 7q31 localizes a putative tumor suppressor gene for breast cancer in the region of MET. Oncogene. 13:1996;2001-2008.
    • (1996) Oncogene , vol.13 , pp. 2001-2008
    • Lin, J.C.1    Scherer, S.W.2    Tougas, L.3    Traverso, G.4    Tsui, L.C.5    Andrulis, I.L.6    Jothy, S.7    Park, M.8
  • 18
    • 0032498628 scopus 로고    scopus 로고
    • Caveolin transfection results in caveolae formation but not apical sorting of glycosylphosphatidylinositol (GPI)-anchored proteins in epithelial cells
    • Lipardi C., Mora R., Colomer V., Paladino S., Nitsch L., Rodriguez-Boulan E., Zurzolo C. Caveolin transfection results in caveolae formation but not apical sorting of glycosylphosphatidylinositol (GPI)-anchored proteins in epithelial cells. J. Cell Biol. 140:1998;616-626.
    • (1998) J. Cell Biol. , vol.140 , pp. 616-626
    • Lipardi, C.1    Mora, R.2    Colomer, V.3    Paladino, S.4    Nitsch, L.5    Rodriguez-Boulan, E.6    Zurzolo, C.7
  • 19
    • 0028998554 scopus 로고
    • VIP21-caveolin, a membrane protein constituent of the caveolar coat, oligomerizes in vivo and in vitro
    • Monier S., Parton R.G., Vogel F., Behlke J., Henske A., Kurzchalia T.V. VIP21-caveolin, a membrane protein constituent of the caveolar coat, oligomerizes in vivo and in vitro. Mol. Biol. Cell. 6:1995;911-927.
    • (1995) Mol. Biol. Cell , vol.6 , pp. 911-927
    • Monier, S.1    Parton, R.G.2    Vogel, F.3    Behlke, J.4    Henske, A.5    Kurzchalia, T.V.6
  • 20
    • 0030591426 scopus 로고    scopus 로고
    • Oligomerization of VIP21-caveolin in vitro is stabilized by long chain fatty acylation or cholesterol
    • Monier S., Dietzen D.J., Hastings W.R., Lublin D.M., Kurzchalia T.V. Oligomerization of VIP21-caveolin in vitro is stabilized by long chain fatty acylation or cholesterol. FEBS Lett. 388:1996;143-149.
    • (1996) FEBS Lett. , vol.388 , pp. 143-149
    • Monier, S.1    Dietzen, D.J.2    Hastings, W.R.3    Lublin, D.M.4    Kurzchalia, T.V.5
  • 22
    • 0032489443 scopus 로고    scopus 로고
    • Caveolins, a family of scaffolding proteins for organizing preassembled signalling complexes at the plasma membrane
    • Okamoto T., Schlegel A., Scherer P.E., Lisanti M.P. Caveolins, a family of scaffolding proteins for organizing preassembled signalling complexes at the plasma membrane. J. Biol. Chem. 273:1998;5419-5422.
    • (1998) J. Biol. Chem. , vol.273 , pp. 5419-5422
    • Okamoto, T.1    Schlegel, A.2    Scherer, P.E.3    Lisanti, M.P.4
  • 23
  • 25
    • 0030604717 scopus 로고    scopus 로고
    • Sterol-regulated release of SREBP-2 from cell membranes requires two sequential cleavages, one within a transmembrane segment
    • Sakai J., Duncan E.A., Rawson R.B., Hua X., Brown M.S., Goldstein J.L. Sterol-regulated release of SREBP-2 from cell membranes requires two sequential cleavages, one within a transmembrane segment. Cell. 85:1996;1037-1046.
    • (1996) Cell , vol.85 , pp. 1037-1046
    • Sakai, J.1    Duncan, E.A.2    Rawson, R.B.3    Hua, X.4    Brown, M.S.5    Goldstein, J.L.6
  • 28
    • 0029003932 scopus 로고
    • Caveolin isoforms differ in their N-terminal protein sequence and subcellular distribution. Identification and epitope mapping of an isoform-specific monoclonal antibody probe
    • 395-16 401
    • Scherer P.E., Tang Z., Chun M., Sargiacomo M., Lodish H.F., Lisanti M.P. Caveolin isoforms differ in their N-terminal protein sequence and subcellular distribution. Identification and epitope mapping of an isoform-specific monoclonal antibody probe. J. Biol. Chem. 270:1995;16 395-16 401.
    • (1995) J. Biol. Chem. , vol.270 , pp. 16
    • Scherer, P.E.1    Tang, Z.2    Chun, M.3    Sargiacomo, M.4    Lodish, H.F.5    Lisanti, M.P.6
  • 30
    • 0030949124 scopus 로고    scopus 로고
    • Functional rafts in cell membranes
    • Simons K., Ikonen E. Functional rafts in cell membranes. Nature. 387:1997;569-572.
    • (1997) Nature , vol.387 , pp. 569-572
    • Simons, K.1    Ikonen, E.2
  • 31
    • 0027490174 scopus 로고
    • SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene
    • Yokoyama C., Wang X., Briggs M.R., Admon A., Wu J., Hua X., Goldstein J.L., Brown M.S. SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene. Cell. 75:1993;187-197.
    • (1993) Cell , vol.75 , pp. 187-197
    • Yokoyama, C.1    Wang, X.2    Briggs, M.R.3    Admon, A.4    Wu, J.5    Hua, X.6    Goldstein, J.L.7    Brown, M.S.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.