The supramolecular organization of fibrillin-rich microfibrils

Journal of Cell Biology

Volumn 152, Issue 5, 2001, Pages 1045-1056

  Baldock, Clair ^a   Koster, Abraham J ^b   Ziese, Ulrike ^b   Rock, Matthew J ^a   Sherratt, Michael J ^a   Kadler, Karl E ^a   Adrian Shuttleworth, C ^a   Kielty, Cay M ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Automated electron tomography; Fibrillin microfibrils; Molecular alignment; Scanning transmission electron microscopy mass mapping; Three dimensional reconstruction

Indexed keywords

ANTIBODY; FIBRILLIN; GOLD; PROLINE;

ANIMAL CELL; ANTIBODY COMBINING SITE; ARTICLE; AUTOMATION; CARBOXY TERMINAL SEQUENCE; COLLOID; CONFORMATIONAL TRANSITION; ELECTRON MICROSCOPY; EPITOPE MAPPING; FIBER; HUMAN; HUMAN CELL; IMAGE RECONSTRUCTION; IMMUNOFLUORESCENCE; MOLECULAR MODEL; MOLECULAR STABILITY; NONHUMAN; OPTICAL RESOLUTION; PERIODICITY; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN STRUCTURE; STRUCTURE ANALYSIS; SUPRAMOLECULAR CHEMISTRY; THREE DIMENSIONAL IMAGING;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES; AUTOMATION; BINDING SITES, ANTIBODY; BIOPOLYMERS; CATTLE; CELLS, CULTURED; EPIDERMAL GROWTH FACTOR; FIBROBLASTS; FLUORESCENT ANTIBODY TECHNIQUE; GOLD COLLOID; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MICROFIBRILS; MICROFILAMENT PROTEINS; MICROSCOPY, ELECTRON, SCANNING TRANSMISSION; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUSCLE TONUS; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; TOMOGRAPHY;

ANIMALIA;

EID: 0035809912     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.152.5.1045     Document Type: Article

References (50)

1. Regulation of fibrillin carboxy-terminal furin processing by N-glycosytation, and association of amino- and carboxy-terminal sequences
2. Fibrillin degradation by matrix metalloproteinases: Implications for connective tissue remodelling
3. Fibrillin assembly: Dimer formation mediated by amino-terminal sequences
4. Metal ion dependency of microfibrils supports a rod-like conformation for fibrillin-1 calcium-binding epidermal growth factor-like domains
5. Role of the latent transforming growth factor beta binding protein 1 in fibrillin-containing microfibrils in bone cells in vitro and in vivo
6. Influence of the water-air interface on the apparent surface tension of aqueous solutions of hydrophilic solutes
7. Solution structure of a pair of calcium binding epidermal growth factor-like domains: Implications for the Marfan syndrome and other genetic disorders
8. Rotary shadowing of collagen monomers, oligomers and fibrils during tendon fibrillogenesis
9. New insights into the assembly of extracellular microfibrils from the analysis of the fibrillin 1 mutation in the tight skin mouse
10. Fibrillin: From domain structure to supramolecular assembly
11. Atomic force microscopy and modelling of natural elastic fibrillin polymers
12. Preparation of colloidal-gold-labelled proteins
13. Extraction of beaded structures and their identification as fibrillin-containing matrix microfibrils
14. Isolation and ultrastructural analysis of microfibrillar structures from foetal bovine elastic tissues. Relative abundance and supramolecular architecture of type VI collagen assemblies and fibrillin
15. The role of calcium in the organisation of fibrillin microfibrils
16. Fibrillin-containing microfibrils - Structure and function in health and disease
17. Computer visualisation of three-dimensional image data using IMOD
18. Connective tissue microfibrils: Isolation and characterisation of three large pepsin-resistant domains of fibrillin
19. Partial sequence of a candidate gene for the Marfan-Syndrome
20. The elastic fiber
21. The modulus of elasticity of lobster aorta microfibrils
22. Genomic organization of the sequence coding for fibrillin, the defective gene product in Marfan syndrome
23. Cell adhesion and integrin binding to recombinant human fibrillin-1
24. Alignment of fibrillin molecules in elastic microfibrils is defined by transglutaminase-derived cross-links
25. Carboxy-terminal conversion of profibrillin to fibrillin at a basic site by PACE/furin-like activity required for incorporation in the matrix
26. Fibrillin-1: Organisation in microfibrils and structural properties
27. Calcium determines the shape of fibrillin
28. Mutations in calcium-binding epidermal growth factor modules render fibrillin-1 susceptible to proteolysis
29. An analysis by rotary shadowing of the structure of the mammalian vitreous humor and zonular apparatus
30. Processing of the fibrillin-1 carboxyl-terminal domain
31. The molecular genetics of Marfan Syndrome and related microfibrillopathies
32. Fibrillin, a new 350-kd glycoprotein, is a component of extracellular microfibrils
33. Purification and partial characterisation of fibrillin, a cysteine-rich structural component of connective tissue microfibrils
34. Cell-type specific recognition of RGD- and non-RGD-containing cell binding domains in fibrillin-1
35. Structure of Lumbricus terrestris hemoglobin at 30Å resolution determined using angular reconstitution
36. Scanning transmission electron microscopy mass analysis of fibrillin-containing microfibrils from foetal elastic tissues
37. Fibrillin-rich microfibrils of the extracellular matrix: Ultrastructure and assembly
38. Cellular and extracellular biology of the latent transforming growth factor-beta binding proteins
39. Morphology and biomechanics of the microfibrillar network of sea cucumber dermis
40. Partial biochemical and immunologic characterization of fibrillin microfibrils from sea cucumber dermis
41. N-terminal domains of fibrillin 1 and fibrillin 2 direct the formation of homodimers: A possible first step in microfibril assembly
42. The microfibrillar proteins MAGP-1 and fibrillin-1 form a ternary complex with the chondroitin sulfate proteoglycan decorin
43. Rotary shadowing of elastic system microfibrils in the ocular zonule, vitreous and ligamentum nuchae
44. Calcium determines the supramolecular organization of fibrillin-rich microfibrils
45. X-ray diffraction studies of fibrillin-rich microfibrils: Effects of tissue extension on axial and lateral packing
46. The supramolecular organisation of fibrillin-rich microfibrils determines the mechanical properties of bovine zonular filaments
47. Vitreous humor of chicken contains two fibrillar systems: An analysis of their structures
48. Solution structure of the transforming growth factor beta-binding protein-like module, a domain associated with matrix fibrils
49. Effects of proline cis-trans isomerisation on TB domain secondary structure
50. Structure and expression of fibrillin-2, a novel microfibrillar component preferentially located in elastic matrices