BMS-196085: A potent and selective full agonist of the human β3 adrenergic receptor

Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 23, 2001, Pages 3041-3044

  Gavai, A V ^a   Sher, P M ^a   Mikkilineni, A B ^a   Poss, K M ^a   McCann, P J ^a   Girotra, R N ^a   Fisher, L G ^a   Wu, G ^a   Bednarz, M S ^a   Mathur, A ^a   Wang, T C ^a   Sun, C Q ^a   Slusarchyk, D A ^a   Skwish, S ^a   Allen, G T ^a   Hillyer, D E ^a   Frohlich, B H ^a   Abboa Offei, B E ^a   Cap, M ^a   Waldron, T L ^a   George, R J ^a   Tesfamariam, B ^a   Harper, T W ^a   Ciosek Jr , C P ^a   Young, D A ^a   Dickinson, K E ^a   Seymour, A A ^a   Arbeeny, C M ^a   Washburn, W N ^a   more..

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXY 3 METHYLSULFONANILIDO 1,2 ETHYLAMINE; BETA 1 ADRENERGIC RECEPTOR; BETA 3 ADRENERGIC RECEPTOR; BETA 3 ADRENERGIC RECEPTOR STIMULATING AGENT; BMS 194449; BMS 196085; ETHYLAMINE; GLUCOSE; PROPRANOLOL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DOSE RESPONSE; DRUG ACTIVITY; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG GLUCURONIDATION; DRUG IDENTIFICATION; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN TISSUE; HYPERGLYCEMIA; MOUSE; NONHUMAN; OBESITY; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION;

ADMINISTRATION, ORAL; ADRENERGIC AGONISTS; ANILIDES; ANIMALS; BLOOD GLUCOSE; CERCOPITHECUS AETHIOPS; DRUG EVALUATION, PRECLINICAL; FATTY ACIDS; HUMANS; MICE; MICE, OBESE; RECEPTORS, ADRENERGIC, BETA-1; RECEPTORS, ADRENERGIC, BETA-3; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035802971     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(01)00629-1     Document Type: Article

References (17)