Engineered Zn2+ switches in the γ-aminobutyric acid (GABA) transporter-1. Differential effects on GABA uptake and currents

Journal of Biological Chemistry

Volumn 276, Issue 44, 2001, Pages 40476-40485

  MacAulay, Nanna ^a   Bendahan, Annie ^b   Loland, Claus Juul ^a   Zeuthen, Thomas ^a   Kanner, Baruch I ^b   Gether, Ulrik ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b HEBREW UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOLOGICAL MEMBRANES;

TRANSIENT CURRENTS;

ZINC;

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID TRANSPORTER 1; CYSTEINE; DOPAMINE TRANSPORTER; HISTIDINE; LITHIUM; SODIUM ION; UNCLASSIFIED DRUG; ZINC ION; 4 AMINOBUTYRIC ACID CARRIER; CARRIER PROTEIN; GABA PERMEASE; MEMBRANE PROTEIN; ORGANIC ANION TRANSPORTER; ZINC;

4 AMINOBUTYRIC ACID UPTAKE; ANIMAL CELL; ARTICLE; CELL CULTURE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CROSS LINKING; EMBRYO; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; RAT; SITE DIRECTED MUTAGENESIS; SODIUM CURRENT; AMINO ACID SEQUENCE; ANIMAL; BINDING SITE; CELL STRAIN COS1; CHEMISTRY; GENETICS; METABOLISM; MOLECULAR GENETICS; XENOPUS LAEVIS;

ANIMALIA; XENOPUS LAEVIS;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CARRIER PROTEINS; COS CELLS; GABA PLASMA MEMBRANE TRANSPORT PROTEINS; GAMMA-AMINOBUTYRIC ACID; MEMBRANE PROTEINS; MEMBRANE TRANSPORT PROTEINS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; ORGANIC ANION TRANSPORTERS; XENOPUS LAEVIS; ZINC;

EID: 0035798631     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M105578200     Document Type: Article

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