A Rho-dependent signaling pathway operating through myosin localizes β-actin mRNA in fibroblasts

Current Biology

Volumn 11, Issue 13, 2001, Pages 1010-1016

  Latham Jr , Vaughan M ^a   Yu, Edward H S ^a   Tullio, Antonella N ^b   Adelstein, Robert S ^b   Singer, Robert H ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0035838320     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(01)00291-3     Document Type: Article

References (35)

1. Relationship between Arp2/3 complex and the barbed ends of actin filaments at the leading edge of carcinoma cells after epidermal growth factor stimulation
2. Sequences responsible for intracellular localization of β-actin messenger RNA also affect cell phenotype
3. Determinants of mRNA localization
4. Characterization of a β-actin mRNA zipcode-binding protein
5. β-actin messenger RNA localization and protein synthesis augment cell motility
6. The physiological significance of mRNA localization in determining cell polarity and directional motility
7. β-actin mRNA localization is regulated by signal transduction mechanisms
8. Rho GTPases and the actin cytoskeleton
9. In vitro ADP ribosylation of Rho by bacterial ADP-ribosyltransferases
10. Inhibition of losophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP binding protein Rho
11. The small GTP binding protein Rho regulates the assembly of focal adhesions and stress fibers in response to growth factors
12. Serum induced signal transduction determines the peripheral localization of β-actin mRNA localization
13. Integrin mediated signals regulated by members of the Rho GTPases
14. Rho effectors and the reorganization of the actin cytoskeleton
15. Calcium sensitization of smooth muscle mediated by a Rho associated protein kinase in hypertension
16. Use and properties of ROCK-specific inhibitor Y-27632
17. P160 ROCK, a Rho-associated coiled-coiled forming protein kinase, work downstream of Rho and induces focal adhesions
18. Identification of a putative target for Rho as the serine-threonine kinase protein kinase N
19. Rho-stimulated contractility drives the formation of stress fibers and focal adhesions
20. Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)
21. Signal transduction by G-proteins, Rho-kinase and protein phosphatase to smooth muscle and non-muscle myosin II
22. The influence of 2,3-butanedione 2-monoxime(BDM) on interaction between actin and myosin in solution and in skinned muscle fiber
23. Myosin is involved in postmitotic cell spreading
24. Effect of protein kinase inhibitor H7 on the contractility, integrity and membrane anchorage of the microfilament system
25. Selective inhibition of catalytic activity of smooth muscle myosin light chain kinase
26. Nonmuscle myosin II-B is required for normal development of the mouse heart
27. Xenopus nonmuscle myosin heavy chain isoforms have different subcellular localizations and enzymatic activities
28. Differential localization of myosin-II isozymes in human cultured cells and blood cells
29. Integrin binding and mechanical tension induce movement of mRNA and ribosomes to focal adhesions
30. Specific localization of serine 19 phosphorylated myosin II during cell locomotion and mitosis of cultured cells
31. Identification of novel graded polarity actin filament bundles in locomoting heart fibroblasts: Implications for the generation of motile force
32. Polarity and velocity of sliding filaments: Control of direction by actin and of speed by myosin
33. Distinct roles of ROCK (Rho-kinase) and MLCK in spatial regulation of MLC phosphorylation for assembly of stress fibers and focal adhesions in 3T3 fibroblasts
34. Antigen-induced secretion of histamine and the phosphorylation of myosin by protein kinase C in rat basophilic leukemia cells
35. Two nonmuscle myosin II heavy chain isoforms expressed in rabbit brains: Filament forming properties, the effects of phosphorylation by protein kinase C and casein kinase II, and location of the phosphorylation sites