Actin depolymerizing factor stabilizes an existing state of F-actin and can change the tilt of F-actin subunits

Journal of Cell Biology

Volumn 153, Issue 1, 2001, Pages 75-86

  Galkin, Vitold E ^a,b   Orlova, Albina ^a   Lukoyanova, Natalya ^a,c   Wriggersd, Willy ^d   Egelman, Edward H ^a  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

^b INSTITUTE OF CYTOLOGY   (Russian Federation)

^c INSTITUTE OF THEORETICAL AND EXPERIMENTAL BIOPHYSICS   (Russian Federation)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Actin; ADF; Cooperativity; Electron microscopy; Image processing

Indexed keywords

ACTIN; ACTIN DEPOLYMERIZING FACTOR; F ACTIN;

ANIMAL TISSUE; ARTICLE; CELL MOTILITY; COMPLEX FORMATION; ELECTRON MICROSCOPY; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN STABILITY; RABBIT;

ACTIN DEPOLYMERIZING FACTORS; ACTINS; ANIMALS; DESTRIN; HUMANS; MICROFILAMENT PROTEINS; MODELS, MOLECULAR; RABBITS;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 0035795407     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.153.1.75     Document Type: Article

References (57)

1. Proteins of the ADF/cofilin family: Essential regulators of actin dynamics
2. Putting a new twist on actin: ADF/cofilins modulate actin dynamics
3. Intracellular pH modulation of ADF/cofilin proteins
4. Mechanism of interaction of Acanthamoeba actophorin (ADF/Cofilin) with actin filaments
5. Control of actin dynamics
6. Control of actin dynamics in cell motility
7. Actin depolymerizing factor (ADF/cofilin) enhances the rate of filament turnover: Implication in actin-based motility
8. Regulating actin-filament dynamics in vivo
9. Purification and characterization of actophorin, a new 15,000-dalton actin-binding protein from Acanthamoeba castellanii
10. Alteration in crossbridge kinetics caused by mutations in actin
11. Kinetic studies on the effect of yeast cofilin on yeast actin polymerization
12. A robust algorithm for the reconstruction of helical filaments using single-particle methods
13. Structural studies of F-actin
14. F-actin is a helix with a random variable twist
15. Axial period of actin filaments: Electron microscope studies
16. Tertiary structure of destrin and structural similarity between two actin-regulating protein families
17. Human actin depolymerizing factor mediates a pH-sensitive destruction of actin filaments
18. Analysis of the interactions of actin depolymerizing factor with G- and F-actin
19. Atomic model of the actin filament
20. VMD: Visual molecular dynamics
21. X-ray diffraction measurements of the extensibility of actin and myosin filaments in contracting muscle
22. Intrastrand cross-linked actin between Gln-41 and Cys-374. III. Inhibition of motion and force generation with myosin
23. Essential functions and actin-binding surfaces of yeast cofilin revealed by systematic mutagenesis
24. Supercoiling of F-actin filaments
25. Characterization of actin filament severing by actophorin from Acanthamoeba castellanii
26. The effect of two actin depolymerizing factors (ADF/cofilins) on actin filament turnover: pH sensitivity of F-actin binding by human ADF, but not of Acanthamoeba actophorin
27. ADF/cofilin weakens lateral contacts in the actin filament
28. Cofilin changes the twist of F-actin: Implications for actin filament dynamics and cellular function
29. Two activities of cofilin, severing and accelerating directional depolymerization of actin filaments, are affected differentially by mutations around the actin-binding helix
30. UNC-60B, an ADF/cofilin family protein, is required for proper assembly of actin into myofibrils in Caenorhabditis elegans body wall muscle
31. Structural dynamics of F-actin. I. Changes in the C-terminus
32. Cooperative rigor binding of myosin to actin is a function of F-Actin structure
33. F-actin retains a memory of angular order
34. Structural dynamics of F-actin. II. Co-operativity in structural transitions
35. A 13 A map of the actin-scruin filament from the limulus acrosomal process
36. Molecular mechanisms controlling actin filament dynamics in nonmuscle cells
37. Uncoupling actin filament fragmentation by cofilin from increased subunit turnover
38. Inhibition of sliding movement of F-actin by cross-linking emphasizes the role of actin structure in the mechanism of motility
39. The identification of a second cofilin binding site on actin suggests a novel, intercalated arrangement of F-actin binding
40. Kinetic analysis of the interaction of actin-depolymerizing factor (ADF)/cofilin with G- and F-actins. Comparison of plant and human ADFs and effect of phosphorylation
41. Aip1p interacts with cofilin to disassemble actin filaments
42. The correlation averaging of a regularly arranged bacterial cell envelope protein
43. Subtilisin cleavage of actin inhibits in vitro siding movement of actin filaments over myosin
44. Chicken-gizzard actin: Polymerization and stability
45. Improved method for mapping the binding site of an actin-binding protein in the actin sequence. Use of a site-directed anti-body against the N-terminal region of actin as a probe of its N-terminus
46. End-label finger printings show that an N-terminal segment of depactin participates in interaction with actin
47. Accelerating on a treadmill: ADF/cofilin promotes rapid actin filament turnover in the dynamic cytoskeleton
48. Actin filaments, stereocilia, and hair cells of the bird cochlea. II. Packing of actin filaments in the stereocilia and in the cuticular plate and what happens to the organization when the stereocilia are bent
49. Algorithms for macromolecular dynamics and constraint dynamics
50. Analogous F-actin binding by cofilin and gelsolin segment 2 substantiates their structural relationship
51. X-ray diffraction evidence for the extensibility of actin and myosin filaments during muscle contraction
52. Using Situs for flexible and rigid-body fitting of multi-resolution single molecule data
53. Investigating a back door mechanism of actin phosphate release by steered molecular dynamics
54. Self-organizing neural networks bridge the biomolecular resolution gap
55. Situs: A package for docking crystal structures into low-resolution maps from electron microscopy
56. pH control of actin polymerization by cofilin
57. Inhibition of actin polymerization by a synthetic dodecapeptide patterned on the sequence around the actin-binding site of cofilin