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Volumn 12, Issue 2, 2001, Pages 163-171

Uptake and metabolism of exogenous glycosphingolipids by cultured cells

Author keywords

Biotin GM1; Endocytosis; Exogenous gangliosides; Ganglioside function; Ganglioside transport; Intralysosomal membranes; Semi truncated glycolipids

Indexed keywords

ACYLSPHINGOSINE DEACYLASE; GANGLIOSIDE; GLUCOSYLCERAMIDE; GLYCOLIPID; GLYCOSPHINGOLIPID; LACTOSYLCERAMIDE; THIOGLYCOSIDE;

EID: 0035783078     PISSN: 10849521     EISSN: None     Source Type: Journal    
DOI: 10.1006/scdb.2000.0233     Document Type: Article
Times cited : (55)

References (97)
  • 1
    • 0002130926 scopus 로고
    • The ganglioside
    • Agranoff BW, Aprison MH, eds. Plenum, New York
    • Wiegandt H (1982) The ganglioside, in Advances in Neu-rochemistry (Agranoff BW, Aprison MH, eds) pp. 149-223. Plenum, New York
    • (1982) Advances in Neurochemistry , pp. 149-223
    • Wiegandt, H.1
  • 2
    • 0015876764 scopus 로고
    • Membrane structure: Some general principles
    • Bretscher MS (1973) Membrane structure: Some general principles. Science 181:622-629
    • (1973) Science , vol.181 , pp. 622-629
    • Bretscher, M.S.1
  • 3
    • 0021943517 scopus 로고
    • Gangliosides of the neuron
    • Ledeen R (1985) Gangliosides of the neuron. Trends Neurosci 8:169-174
    • (1985) Trends Neurosci , vol.8 , pp. 169-174
    • Ledeen, R.1
  • 4
    • 0015859264 scopus 로고
    • External labeling of cell surface galactose and galactosamine in glycolipid and glycoprotein of human erythrocytes
    • Gahmberg CT, Hakomori SI (1973) External labeling of cell surface galactose and galactosamine in glycolipid and glycoprotein of human erythrocytes. J Biol Chem 248:4311-4317
    • (1973) J Biol Chem , vol.248 , pp. 4311-4317
    • Gahmberg, C.T.1    Hakomori, S.I.2
  • 5
    • 0021979912 scopus 로고
    • Organization of glycosphingolipids in bilayers and plasma membranes of mammalian cells
    • Thompson TE, Tillack TW (1985) Organization of glycosphingolipids in bilayers and plasma membranes of mammalian cells. Annu Rev Biophys Chem 14:361-386
    • (1985) Annu Rev Biophys Chem , vol.14 , pp. 361-386
    • Thompson, T.E.1    Tillack, T.W.2
  • 6
    • 0019363342 scopus 로고
    • Glycosphingolipids in cellular interaction, differentiation, and oncogenesis
    • Hakomori S-I (1981) Glycosphingolipids in cellular interaction, differentiation, and oncogenesis. Annu Rev Biochem 50:733-764
    • (1981) Annu Rev Biochem , vol.50 , pp. 733-764
    • Hakomori, S.-I.1
  • 7
    • 0021710314 scopus 로고
    • A multivalent lacto-N-fucopentaose III-lysyllysine conjugate decompacts preimplantation mouse embryos, while the free oligosaccharide is ineffective
    • Fenderson BA, Zehavi U, Hakomori S (1985) A multivalent lacto-N-fucopentaose III-lysyllysine conjugate decompacts preimplantation mouse embryos, while the free oligosaccharide is ineffective. J Exp Med 160:1591-1596
    • (1985) J Exp Med , vol.160 , pp. 1591-1596
    • Fenderson, B.A.1    Zehavi, U.2    Hakomori, S.3
  • 8
    • 0021231873 scopus 로고
    • Cellular distribution of gangliosides in the developing mouse cerebellum: Analysis using the staggerer mutant
    • Seyfried TN, Bernard DJ, Yu RK (1984) Cellular distribution of gangliosides in the developing mouse cerebellum: Analysis using the staggerer mutant. J Neurochem 43:1152-1162
    • (1984) J Neurochem , vol.43 , pp. 1152-1162
    • Seyfried, T.N.1    Bernard, D.J.2    Yu, R.K.3
  • 9
    • 0025077629 scopus 로고
    • Bifunctional role of glycosphingolipids. Modulators for transmembrane signaling and mediators for cellular interactions
    • Hakomori S (1990) Bifunctional role of glycosphingolipids. Modulators for transmembrane signaling and mediators for cellular interactions. J Biol Chem 265:18713-18716
    • (1990) J Biol Chem , vol.265 , pp. 18713-18716
    • Hakomori, S.1
  • 10
    • 0032502722 scopus 로고    scopus 로고
    • GM3-enriched microdomain involved in cell adhesion and signal transduction through carbohydrate-carbohydrate interaction in mouse melanoma B16 cells
    • Iwabuchi K, Yamamura S, Prinetti A, Handa K, Hakomori S (1998) GM3-enriched microdomain involved in cell adhesion and signal transduction through carbohydrate-carbohydrate interaction in mouse melanoma B16 cells. J Biol Chem 273:9130-9138
    • (1998) J Biol Chem , vol.273 , pp. 9130-9138
    • Iwabuchi, K.1    Yamamura, S.2    Prinetti, A.3    Handa, K.4    Hakomori, S.5
  • 11
    • 0032055206 scopus 로고    scopus 로고
    • Dual role of ceramide in the control of apoptosis following IL-2 withdrawal
    • Flores I, Martinez A C, Hannun YA, Merida I (1998) Dual role of ceramide in the control of apoptosis following IL-2 withdrawal. J Immunol 160:3528-3533
    • (1998) J Immunol , vol.160 , pp. 3528-3533
    • Flores, I.1    Martinez, A.C.2    Hannun, Y.A.3    Merida, I.4
  • 12
    • 0029609895 scopus 로고
    • Functional role of glycosphingolipids in cell recognition and signaling
    • Hakomori S, Igarashi Y (1995) Functional role of glycosphingolipids in cell recognition and signaling. J Biochem 118:1091-1103
    • (1995) J Biochem , vol.118 , pp. 1091-1103
    • Hakomori, S.1    Igarashi, Y.2
  • 13
    • 0032509947 scopus 로고    scopus 로고
    • Membrane biology: Do glycolipid microdomains really exist?
    • Hooper NM (1998) Membrane biology: Do glycolipid microdomains really exist? Curr Biol 8:R114-R116
    • (1998) Curr Biol , vol.8
    • Hooper, N.M.1
  • 14
    • 0030878573 scopus 로고    scopus 로고
    • Caveolae, DIGs, and the dynamics of sphingolipid-cholesterol microdomains
    • Harder T, Simons K (1997) Caveolae, DIGs, and the dynamics of sphingolipid-cholesterol microdomains. Curr Opin Cell Biol 9:534-542
    • (1997) Curr Opin Cell Biol , vol.9 , pp. 534-542
    • Harder, T.1    Simons, K.2
  • 15
    • 0025689587 scopus 로고
    • Metabolism and intracellular transport of glycosphingolipids
    • Schwarzmann G, Sandhoff K (1990) Metabolism and intracellular transport of glycosphingolipids. Biochemistry 29:10865-10871
    • (1990) Biochemistry , vol.29 , pp. 10865-10871
    • Schwarzmann, G.1    Sandhoff, K.2
  • 16
    • 0016326515 scopus 로고
    • Ganglioside accumulation by transformed murine fibroblast (3T3) cells and canine erythrocytes
    • Keenan TW, Franke WW, Wiegandt H (1974) Ganglioside accumulation by transformed murine fibroblast (3T3) cells and canine erythrocytes. Hoppe-Seyler's Z Physiol Chem 355:1543-1558
    • (1974) Hoppe-Seyler's Z Physiol Chem , vol.355 , pp. 1543-1558
    • Keenan, T.W.1    Franke, W.W.2    Wiegandt, H.3
  • 17
    • 0017576431 scopus 로고
    • Synthesis and uptake of gangliosides by choleragen-responsive human fibroblasts
    • Fishman PH, Moss J, Manganiello VC (1977) Synthesis and uptake of gangliosides by choleragen-responsive human fibroblasts. Biochemistry 16:1871-1875
    • (1977) Biochemistry , vol.16 , pp. 1871-1875
    • Fishman, P.H.1    Moss, J.2    Manganiello, V.C.3
  • 18
    • 0025006418 scopus 로고
    • Effect of the different supramolecular organization on the uptake and metabolization of exogenous GM1 ganglioside by human fibroblasts
    • Giglioni A, Chigorno V, Pitto M, Valsecchi M, Palestini P, Ghidoni R (1990) Effect of the different supramolecular organization on the uptake and metabolization of exogenous GM1 ganglioside by human fibroblasts. Chem Phys Lipids 55:207-213
    • (1990) Chem Phys Lipids , vol.55 , pp. 207-213
    • Giglioni, A.1    Chigorno, V.2    Pitto, M.3    Valsecchi, M.4    Palestini, P.5    Ghidoni, R.6
  • 19
    • 0024388562 scopus 로고
    • Astrocytes in cell culture incorporate GM1 ganglioside
    • Masco D, Flott B, Seifert W (1989) Astrocytes in cell culture incorporate GM1 ganglioside. Glia 2:231-240
    • (1989) Glia , vol.2 , pp. 231-240
    • Masco, D.1    Flott, B.2    Seifert, W.3
  • 20
    • 0024353403 scopus 로고
    • Incorporation of exogenous ganglioside GM1 into neuroblastoma membranes: Inhibition by calcium ion and dependence upon membrane protein
    • Leskawa KC, Erwin RE, Leon A, Toffano G, Hogan EL (1989) Incorporation of exogenous ganglioside GM1 into neuroblastoma membranes: Inhibition by calcium ion and dependence upon membrane protein. Neurochem Res 14:547-554
    • (1989) Neurochem Res , vol.14 , pp. 547-554
    • Leskawa, K.C.1    Erwin, R.E.2    Leon, A.3    Toffano, G.4    Hogan, E.L.5
  • 21
    • 0019332821 scopus 로고
    • Modification of ganglioside GM1: Effect of lipid moiety on choleragen action
    • Fishman PH, Pacuszka T, Hom B, Moss J (1980) Modification of ganglioside GM1: Effect of lipid moiety on choleragen action. J Biol Chem 255:7657-7664
    • (1980) J Biol Chem , vol.255 , pp. 7657-7664
    • Fishman, P.H.1    Pacuszka, T.2    Hom, B.3    Moss, J.4
  • 22
    • 0018824558 scopus 로고
    • Surface distribution of monosialoganglioside GM1 on human blood cells and the effect of exogenous GM1 and neuraminidase on cholera toxin surface labeling
    • Ackerman GQ, Wolken KW, Gelder FB (1980) Surface distribution of monosialoganglioside GM1 on human blood cells and the effect of exogenous GM1 and neuraminidase on cholera toxin surface labeling. J Histochem Cytochem 28:1100-1112
    • (1980) J Histochem Cytochem , vol.28 , pp. 1100-1112
    • Ackerman, G.Q.1    Wolken, K.W.2    Gelder, F.B.3
  • 23
    • 0018900271 scopus 로고
    • Binding of monosialoganglioside by murine thymus cells in vitro
    • Krishnaraj R, Saat YA, Kemp RG (1980) Binding of monosialoganglioside by murine thymus cells in vitro. Cancer Res 40:2808-2813
    • (1980) Cancer Res , vol.40 , pp. 2808-2813
    • Krishnaraj, R.1    Saat, Y.A.2    Kemp, R.G.3
  • 24
    • 0018399573 scopus 로고
    • Growth factors and gangliosides: A possible new perspective in neuronal growth control
    • Morgan L, Seifert W (1979) Growth factors and gangliosides: A possible new perspective in neuronal growth control. J Supramol Struct 10:111-124
    • (1979) J Supramol Struct , vol.10 , pp. 111-124
    • Morgan, L.1    Seifert, W.2
  • 25
    • 0021026958 scopus 로고
    • Ganglioside-induced neuritogenesis: Verification that gangliosides are the active agents, comparison of molecular species
    • Byrne MC, Ledeen RW, Roisen FJ, Yorke G, Sclafani JR (1983) Ganglioside-induced neuritogenesis: Verification that gangliosides are the active agents, comparison of molecular species. J Neurochem 41:1214-1222
    • (1983) J Neurochem , vol.41 , pp. 1214-1222
    • Byrne, M.C.1    Ledeen, R.W.2    Roisen, F.J.3    Yorke, G.4    Sclafani, J.R.5
  • 26
    • 0021327310 scopus 로고
    • Promotion of neuritogenesis in mouse neuroblastoma cells by exogenous gangliosides. Relationship between the effect and the cell association of ganglioside GM1
    • Facci L, Leon A, Toffano G, Sonnino S, Ghidoni R, Tettamanti G (1984) Promotion of neuritogenesis in mouse neuroblastoma cells by exogenous gangliosides. Relationship between the effect and the cell association of ganglioside GM1. J Neurochem 42:299-305
    • (1984) J Neurochem , vol.42 , pp. 299-305
    • Facci, L.1    Leon, A.2    Toffano, G.3    Sonnino, S.4    Ghidoni, R.5    Tettamanti, G.6
  • 27
    • 0025021931 scopus 로고
    • The role(s) of gangliosides in neural differentiation and repair: A perspective
    • Schengrund C-L (1990) The role(s) of gangliosides in neural differentiation and repair: A perspective. Brain Res Bull 24:131-141
    • (1990) Brain Res Bull , vol.24 , pp. 131-141
    • Schengrund, C.-L.1
  • 28
    • 0023737884 scopus 로고
    • A novel, carbohydrate signal-mediated cell surface protein phosphorylation: Ganglioside GQ1b stimulates ecto-protein kinase activity on the cell surface of a human neuroblastoma cell line, GOTO
    • Tsuji S, Yamashita T, Nagai Y (1988) A novel, carbohydrate signal-mediated cell surface protein phosphorylation: Ganglioside GQ1b stimulates ecto-protein kinase activity on the cell surface of a human neuroblastoma cell line, GOTO. J Biochem 104:498-503
    • (1988) J Biochem , vol.104 , pp. 498-503
    • Tsuji, S.1    Yamashita, T.2    Nagai, Y.3
  • 29
    • 0002576355 scopus 로고
    • Comparison of exogenous and endogenous gangliosides as modulators of neuronal differentiation
    • Horrocks LA, Neff NH, Yates AJ, Hadjiconstantinou M, eds. Raven Press, New York
    • Ledeen RW, Wu G, Vaswani KK, Canella MS (1990) Comparison of exogenous and endogenous gangliosides as modulators of neuronal differentiation, in Trophic Factors and the Nervous System (Horrocks LA, Neff NH, Yates AJ, Hadjiconstantinou M, eds) pp. 17-34. Raven Press, New York
    • (1990) Trophic Factors and the Nervous System , pp. 17-34
    • Ledeen, R.W.1    Wu, G.2    Vaswani, K.K.3    Canella, M.S.4
  • 30
    • 0021162598 scopus 로고
    • Effect of ganglioside treatment on lesion-induced behavioral impairments and sprouting in the CNS
    • Fass B, Ramirez JJ (1984) Effect of ganglioside treatment on lesion-induced behavioral impairments and sprouting in the CNS. J Neurosci Res 12:445-458
    • (1984) J Neurosci Res , vol.12 , pp. 445-458
    • Fass, B.1    Ramirez, J.J.2
  • 31
    • 0018380238 scopus 로고
    • Effects of gangliosides on adenylate cyclase activity in rat cerebral cortical membranes
    • Partington CR, Daly JW (1979) Effects of gangliosides on adenylate cyclase activity in rat cerebral cortical membranes. Mol Pharmacol 15:484-491
    • (1979) Mol Pharmacol , vol.15 , pp. 484-491
    • Partington, C.R.1    Daly, J.W.2
  • 32
    • 0021186166 scopus 로고
    • Ganglioside-mediated modulation of cell growth, growth factor binding and receptor phosphorylation
    • Bremer EG, Hakomori S, Bowen-Pope DF, Raines E, Ross R (1984) Ganglioside-mediated modulation of cell growth, growth factor binding and receptor phosphorylation. J Biol Chem 259:6818-6825
    • (1984) J Biol Chem , vol.259 , pp. 6818-6825
    • Bremer, E.G.1    Hakomori, S.2    Bowen-Pope, D.F.3    Raines, E.4    Ross, R.5
  • 33
    • 0020033294 scopus 로고
    • Morphological and biochemical effects of gangliosides in neuroblastoma cells
    • Leon A, Facci L, Benvegnu D, Toffano G (1982) Morphological and biochemical effects of gangliosides in neuroblastoma cells. Dev Neurosci 5:108-114
    • (1982) Dev Neurosci , vol.5 , pp. 108-114
    • Leon, A.1    Facci, L.2    Benvegnu, D.3    Toffano, G.4
  • 35
    • 0023025941 scopus 로고
    • Ganglioside-mediated modulation of cell growth: Specific effects of GM3 on tyrosine phosphorylation of the epidermal growth factor receptor
    • Bremer EG, Schlessinger J, Hakomori S (1986) Ganglioside-mediated modulation of cell growth: Specific effects of GM3 on tyrosine phosphorylation of the epidermal growth factor receptor. J Biol Chem 261:2434-2440
    • (1986) J Biol Chem , vol.261 , pp. 2434-2440
    • Bremer, E.G.1    Schlessinger, J.2    Hakomori, S.3
  • 36
    • 0028174902 scopus 로고
    • GM3 directly inhibits tyrosine phosphorylation and de-N-acetyl-GM3 directly enhances serine phosphorylation of epidermal growth factor receptor, independently of receptor-receptor interaction
    • Zhou Q, Hakomori S, Kitamura K, Igarashi Y (1994) GM3 directly inhibits tyrosine phosphorylation and de-N-acetyl-GM3 directly enhances serine phosphorylation of epidermal growth factor receptor, independently of receptor-receptor interaction. J Biol Chem 269:1959-1965
    • (1994) J Biol Chem , vol.269 , pp. 1959-1965
    • Zhou, Q.1    Hakomori, S.2    Kitamura, K.3    Igarashi, Y.4
  • 37
    • 0020336447 scopus 로고
    • GM3 ganglioside induces hamster fibroblast growth inhibition in chemically-defined medium: Ganglioside may regulate growth factor receptor function
    • Bremer EG, Hakomori S (1982) GM3 ganglioside induces hamster fibroblast growth inhibition in chemically-defined medium: Ganglioside may regulate growth factor receptor function. Biochem Biophys Res Commun 106:711-718
    • (1982) Biochem Biophys Res Commun , vol.106 , pp. 711-718
    • Bremer, E.G.1    Hakomori, S.2
  • 38
    • 0034113446 scopus 로고    scopus 로고
    • Effects of GM1 ganglioside treatment on pre- and postsynaptic dopaminergic markers in the striatum of parkinsonian monkeys
    • Pope-Coleman A, Tinker JP, Schneider JS (2000) Effects of GM1 ganglioside treatment on pre- and postsynaptic dopaminergic markers in the striatum of parkinsonian monkeys. Synapse 36:120-128
    • (2000) Synapse , vol.36 , pp. 120-128
    • Pope-Coleman, A.1    Tinker, J.P.2    Schneider, J.S.3
  • 39
    • 0027179047 scopus 로고
    • A review and predictive models of ganglioside uptake by biological membranes
    • Saqr HE, Pearl DK, Yates AJ (1993) A review and predictive models of ganglioside uptake by biological membranes. J Neurochem 61:395-411
    • (1993) J Neurochem , vol.61 , pp. 395-411
    • Saqr, H.E.1    Pearl, D.K.2    Yates, A.J.3
  • 40
    • 0017697007 scopus 로고
    • Characterization of cellular binding of exogenous gangliosides
    • Callies R, Schwarzmann G, Siegert R, Wiegandt H (1977) Characterization of cellular binding of exogenous gangliosides. Eur J Biochem 80:425-432
    • (1977) Eur J Biochem , vol.80 , pp. 425-432
    • Callies, R.1    Schwarzmann, G.2    Siegert, R.3    Wiegandt, H.4
  • 41
    • 0020109107 scopus 로고
    • Studies on the cell association of exogenously added sialo-glycolipids
    • Radsak K, Schwarzmann G, Wiegandt H (1982) Studies on the cell association of exogenously added sialo-glycolipids. Hoppe-Seyler's Z Physiol Chem 363:263-272
    • (1982) Hoppe-Seyler's Z Physiol Chem , vol.363 , pp. 263-272
    • Radsak, K.1    Schwarzmann, G.2    Wiegandt, H.3
  • 42
    • 0021029535 scopus 로고
    • Incorporation of ganglioside analogues into fibroblast cell membranes: A spin-label study
    • Schwarzmann G, Hoffmann-Bleihauer P, Schubert J, Sandhoff K, Marsh D (1983) Incorporation of ganglioside analogues into fibroblast cell membranes: A spin-label study. Biochemistry 22:5041-5048
    • (1983) Biochemistry , vol.22 , pp. 5041-5048
    • Schwarzmann, G.1    Hoffmann-Bleihauer, P.2    Schubert, J.3    Sandhoff, K.4    Marsh, D.5
  • 44
    • 0022789177 scopus 로고
    • Light scattering measurements on gangliosides: Dependance of micellar properties on molecular structure and temperature
    • Cantu L, Corti M, Sonnino S, Tettamanti G (1986) Light scattering measurements on gangliosides: Dependance of micellar properties on molecular structure and temperature. Chem Phys Lipids 41:315-328
    • (1986) Chem Phys Lipids , vol.41 , pp. 315-328
    • Cantu, L.1    Corti, M.2    Sonnino, S.3    Tettamanti, G.4
  • 46
    • 0016231251 scopus 로고
    • Detection of sialic acid containing compounds and the behaviour of gangliosides in polyacrylamide disc electrophoresis
    • Heuser E, Lipp K, Wiegandt H (1974) Detection of sialic acid containing compounds and the behaviour of gangliosides in polyacrylamide disc electrophoresis. Anal Biochem 60:382-388
    • (1974) Anal Biochem , vol.60 , pp. 382-388
    • Heuser, E.1    Lipp, K.2    Wiegandt, H.3
  • 48
    • 0000109221 scopus 로고
    • Physicochemical properties of ox-brain gangliosides
    • Gammack DB (1963) Physicochemical properties of ox-brain gangliosides. Biochem J 88:373-383
    • (1963) Biochem J , vol.88 , pp. 373-383
    • Gammack, D.B.1
  • 50
    • 0018385948 scopus 로고
    • Monomer-micelle transition of ganglioside GM1 and the hydrolysis by Clostridium perfringens neuraminidase
    • Rauvala H (1979) Monomer-micelle transition of ganglioside GM1 and the hydrolysis by Clostridium perfringens neuraminidase. Eur J Biochem 97:555-564
    • (1979) Eur J Biochem , vol.97 , pp. 555-564
    • Rauvala, H.1
  • 53
    • 0019002123 scopus 로고
    • Laser light scattering investigation of the micellar properties of gangliosides
    • Corti M, Degiorgio V, Ghidoni R, Sonnino S, Tettamanti G (1980) Laser light scattering investigation of the micellar properties of gangliosides. Chem Phys Lipids 26:225-238
    • (1980) Chem Phys Lipids , vol.26 , pp. 225-238
    • Corti, M.1    Degiorgio, V.2    Ghidoni, R.3    Sonnino, S.4    Tettamanti, G.5
  • 54
    • 0017102138 scopus 로고
    • C-20-sphingosine as a determining factor in aggregation of gangliosides
    • Yohe HC, Roark DE, Rosenberg A (1976) C-20-sphingosine as a determining factor in aggregation of gangliosides. J Biol Chem 251:7083-7087
    • (1976) J Biol Chem , vol.251 , pp. 7083-7087
    • Yohe, H.C.1    Roark, D.E.2    Rosenberg, A.3
  • 55
    • 0027467490 scopus 로고
    • Ganglioside metabolism. Enzymology, topology, and regulation
    • van Echten G, Sandhoff K (1993) Ganglioside metabolism. Enzymology, topology, and regulation. J Biol Chem 268:5341-5344
    • (1993) J Biol Chem , vol.268 , pp. 5341-5344
    • Van Echten, G.1    Sandhoff, K.2
  • 56
    • 0024448087 scopus 로고
    • Lipid traffic in animal cells
    • van Meer G (1989) Lipid traffic in animal cells. Annu Rev Cell Biol 5:247-275
    • (1989) Annu Rev Cell Biol , vol.5 , pp. 247-275
    • Van Meer, G.1
  • 57
    • 0025064559 scopus 로고
    • Lipid traffic in eucaryotic cells: Mechanisms for intracellular transport and organelle-specific enrichment of lipids
    • Pagano RE (1990) Lipid traffic in eucaryotic cells: Mechanisms for intracellular transport and organelle-specific enrichment of lipids. Curr Opin Cell Biol 2:652-663
    • (1990) Curr Opin Cell Biol , vol.2 , pp. 652-663
    • Pagano, R.E.1
  • 58
    • 0028788772 scopus 로고
    • Golgi staining by two fluorescent ceramide analogues in cultured fibroblasts requires metabolism
    • Pütz U, Schwarzmann G (1995) Golgi staining by two fluorescent ceramide analogues in cultured fibroblasts requires metabolism. Eur J Cell Biol 68:113-121
    • (1995) Eur J Cell Biol , vol.68 , pp. 113-121
    • Pütz, U.1    Schwarzmann, G.2
  • 59
    • 0029791263 scopus 로고    scopus 로고
    • The internalization of a short acyl chain analogue of ganglioside GM1 in polarized neurons
    • Sofer A, Schwarzmann G, Futerman AH (1996) The internalization of a short acyl chain analogue of ganglioside GM1 in polarized neurons. J Cell Sci 109:2111-2119
    • (1996) J Cell Sci , vol.109 , pp. 2111-2119
    • Sofer, A.1    Schwarzmann, G.2    Futerman, A.H.3
  • 60
    • 0001499477 scopus 로고
    • Ultra-structural localization of cell membrane GM1 ganglioside by cholera toxin
    • Hansson HA, Holmgren J, Svennerholm L (1977) Ultra-structural localization of cell membrane GM1 ganglioside by cholera toxin. Proc Natl Acad Sci USA 74:3782-3786
    • (1977) Proc Natl Acad Sci USA , vol.74 , pp. 3782-3786
    • Hansson, H.A.1    Holmgren, J.2    Svennerholm, L.3
  • 61
    • 0028057494 scopus 로고
    • Ultrastructural localization of gangliosides; GM1 is concentrated in caveolae
    • Parton RG (1994) Ultrastructural localization of gangliosides; GM1 is concentrated in caveolae. J Histochem Cytochem 42:155-166
    • (1994) J Histochem Cytochem , vol.42 , pp. 155-166
    • Parton, R.G.1
  • 62
    • 0026337550 scopus 로고
    • Subcellular localization of Forssman glycolipid in epithelial MDCK cells by immuno-electronmicroscopy after freeze-substitution
    • van Genderen IL, van Meer G, Slot JW, Geuze HJ, Voorhout WF (1991) Subcellular localization of Forssman glycolipid in epithelial MDCK cells by immuno-electronmicroscopy after freeze-substitution. J Cell Biol 115:1009-1019
    • (1991) J Cell Biol , vol.115 , pp. 1009-1019
    • Van Genderen, I.L.1    Van Meer, G.2    Slot, J.W.3    Geuze, H.J.4    Voorhout, W.F.5
  • 63
    • 0032799717 scopus 로고    scopus 로고
    • Intracellular distribution of a biotin-labeled ganglioside, GM1, by immunoelectron microscopy after endocytosis in fibroblasts
    • Möbius W, Herzog V, Sandhoff K, Schwarzmann G (1999) Intracellular distribution of a biotin-labeled ganglioside, GM1, by immunoelectron microscopy after endocytosis in fibroblasts. J Histochem Cytochem 47:1005-1014
    • (1999) J Histochem Cytochem , vol.47 , pp. 1005-1014
    • Möbius, W.1    Herzog, V.2    Sandhoff, K.3    Schwarzmann, G.4
  • 64
    • 0032716881 scopus 로고    scopus 로고
    • Gangliosides are transported from the plasma membrane to intralysosomal membranes as revealed by immuno-electron microscopy
    • Möbius W, Herzog V, Sandhoff K, Schwarzmann G (1999) Gangliosides are transported from the plasma membrane to intralysosomal membranes as revealed by immuno-electron microscopy. Biosci Rep 19:307-316
    • (1999) Biosci Rep , vol.19 , pp. 307-316
    • Möbius, W.1    Herzog, V.2    Sandhoff, K.3    Schwarzmann, G.4
  • 65
    • 0031588949 scopus 로고    scopus 로고
    • Synthesis and mass spectrometric characterization of digoxigenin and biotin labeled ganglioside GM1 and their uptake by and metabolism in cultured cells
    • Albrecht B, Pohlentz G, Sandhoff K, Schwarzmann G (1997) Synthesis and mass spectrometric characterization of digoxigenin and biotin labeled ganglioside GM1 and their uptake by and metabolism in cultured cells. Chem Phys Lipids 86:37-50
    • (1997) Chem Phys Lipids , vol.86 , pp. 37-50
    • Albrecht, B.1    Pohlentz, G.2    Sandhoff, K.3    Schwarzmann, G.4
  • 66
    • 0028940724 scopus 로고
    • Delivery to lysosomes in the human carcinoma cell line HEp-2 involves an actin filament-facilitated fusion between mature endosomes and preexisting lysosomes
    • van Deurs B, Holm PK, Kayser L, Sandvig K (1995) Delivery to lysosomes in the human carcinoma cell line HEp-2 involves an actin filament-facilitated fusion between mature endosomes and preexisting lysosomes. Eur J Cell Biol 66:309-323
    • (1995) Eur J Cell Biol , vol.66 , pp. 309-323
    • Van Deurs, B.1    Holm, P.K.2    Kayser, L.3    Sandvig, K.4
  • 67
    • 0029752791 scopus 로고    scopus 로고
    • Endocytosis and molecular sorting
    • Mellman I (1996) Endocytosis and molecular sorting. Annu Rev Dev Biol 12:575-625
    • (1996) Annu Rev Dev Biol , vol.12 , pp. 575-625
    • Mellman, I.1
  • 68
    • 0026747197 scopus 로고
    • Activator proteins and topology of lysosomal sphingolipid catabolism
    • Fürst W, Sandhoff K (1992) Activator proteins and topology of lysosomal sphingolipid catabolism. Biochim Biophys Acta 1126:1-16
    • (1992) Biochim Biophys Acta , vol.1126 , pp. 1-16
    • Fürst, W.1    Sandhoff, K.2
  • 69
    • 0029670774 scopus 로고    scopus 로고
    • Topology of glycosphingolipid degradation
    • Sandhoff K, Kolter T (1996) Topology of glycosphingolipid degradation. Trends Cell Biol 6:98-103
    • (1996) Trends Cell Biol , vol.6 , pp. 98-103
    • Sandhoff, K.1    Kolter, T.2
  • 70
    • 0343052042 scopus 로고    scopus 로고
    • Accumulation of sphingolipids in SAP-precursor (prosaposin)-deficient fibroblasts occurs as intralysosomal membrane structures and can be completely reversed by treatment with human SAP-precursor
    • Burkhardt JK, Hüttler S, Klein A, Möbius W, Habermann A, Grifftiths G, Sandhoff K (1997) Accumulation of sphingolipids in SAP-precursor (prosaposin)-deficient fibroblasts occurs as intralysosomal membrane structures and can be completely reversed by treatment with human SAP-precursor. Eur J Cell Biol 73:10-18
    • (1997) Eur J Cell Biol , vol.73 , pp. 10-18
    • Burkhardt, J.K.1    Hüttler, S.2    Klein, A.3    Möbius, W.4    Habermann, A.5    Grifftiths, G.6    Sandhoff, K.7
  • 71
    • 0025281993 scopus 로고
    • Movement of internalized ligand-receptor complexes along a continuous endosomal reticulum
    • Hopkins CR, Gibson A, Shipman M, Miller K (1990) Movement of internalized ligand-receptor complexes along a continuous endosomal reticulum. Nature 346:335-339
    • (1990) Nature , vol.346 , pp. 335-339
    • Hopkins, C.R.1    Gibson, A.2    Shipman, M.3    Miller, K.4
  • 72
    • 0022861666 scopus 로고
    • Normal- and reverse-phase HPLC separations of fluorescent (NBD) lipids
    • Martin OC, Pagano RE (1986) Normal- and reverse-phase HPLC separations of fluorescent (NBD) lipids. Anal Biochem 159:101-108
    • (1986) Anal Biochem , vol.159 , pp. 101-108
    • Martin, O.C.1    Pagano, R.E.2
  • 73
    • 0024829515 scopus 로고
    • Salvage of glucosylceramide by recycling after internalization along the pathway of receptor-mediated endocytosis
    • Kok JW, Eskelinen S, Hoekstra K, Hoekstra D (1989) Salvage of glucosylceramide by recycling after internalization along the pathway of receptor-mediated endocytosis. Proc Natl Acad Sci USA 86:9896-9900
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 9896-9900
    • Kok, J.W.1    Eskelinen, S.2    Hoekstra, K.3    Hoekstra, D.4
  • 74
    • 0028821993 scopus 로고
    • Synthesis of fluorescent and radioactive analogues of two lactosylceramides and glucosylceramide containing β-thioglycosidic bonds that are resistant to enzymaticdegradation
    • Albrecht B, Pütz U, Schwarzmann G (1995) Synthesis of fluorescent and radioactive analogues of two lactosylceramides and glucosylceramide containing β-thioglycosidic bonds that are resistant to enzymaticdegradation. Carbohydr Res 276:289-308
    • (1995) Carbohydr Res , vol.276 , pp. 289-308
    • Albrecht, B.1    Pütz, U.2    Schwarzmann, G.3
  • 75
    • 0032744717 scopus 로고    scopus 로고
    • Synthesis and characterization of metabolically stable sphingolipids
    • Schwarzmann G (2000) Synthesis and characterization of metabolically stable sphingolipids. Methods Enzymol 311:601-626
    • (2000) Methods Enzymol , vol.311 , pp. 601-626
    • Schwarzmann, G.1
  • 76
    • 0028335260 scopus 로고
    • Internalization and sorting of a fluorescent analogue of glucosylceramide to the Golgi apparatus of human skin fibroblasts: Utilization of endocytic and nonendocytic transport mechanisms
    • Martin OC, Pagano RE (1994) Internalization and sorting of a fluorescent analogue of glucosylceramide to the Golgi apparatus of human skin fibroblasts: Utilization of endocytic and nonendocytic transport mechanisms. J Cell Biol 125:769-781
    • (1994) J Cell Biol , vol.125 , pp. 769-781
    • Martin, O.C.1    Pagano, R.E.2
  • 77
    • 0029133257 scopus 로고
    • Demonstration of direct glycosylation of nondegradable glucosylceramide analogs in cultured cells
    • Schwarzmann G, Hofmann P, Pütz U, Albrecht B (1995) Demonstration of direct glycosylation of nondegradable glucosylceramide analogs in cultured cells. J Biol Chem 270:21271-21276
    • (1995) J Biol Chem , vol.270 , pp. 21271-21276
    • Schwarzmann, G.1    Hofmann, P.2    Pütz, U.3    Albrecht, B.4
  • 78
    • 85029463428 scopus 로고    scopus 로고
    • Evidence for postendocytotic transport in cultured cells of short chain glycolipids from lysosomes to the Golgi apparatus
    • Schwarzmann G, Hofmann P, Pütz U (1997) Evidence for postendocytotic transport in cultured cells of short chain glycolipids from lysosomes to the Golgi apparatus. Glycoconj J 14:S52
    • (1997) Glycoconj J , vol.14
    • Schwarzmann, G.1    Hofmann, P.2    Pütz, U.3
  • 79
    • 0033846952 scopus 로고    scopus 로고
    • Assay for the transbilayer distribution of glycolipids. Selective oxidation of glucosylceramide to glucuronylceramide by tempo nitroxyl radicals
    • Sillence DJ, Raggers RJ, Neville DC, Harvey DJ, van Meer G (2000) Assay for the transbilayer distribution of glycolipids. Selective oxidation of glucosylceramide to glucuronyl-ceramide by tempo nitroxyl radicals. J Lipid Res 41:1252-1260
    • (2000) J Lipid Res , vol.41 , pp. 1252-1260
    • Sillence, D.J.1    Raggers, R.J.2    Neville, D.C.3    Harvey, D.J.4    Van Meer, G.5
  • 80
    • 0021883202 scopus 로고
    • Incorporation and metabolism of ganglioside GM2 in skin fibroblasts from normal and GM2 gangliosidosis subjects
    • Sonderfeld S, Conzelmann E, Schwarzmann G, Burg J, Hinrichs U, Sandhoff K (1985) Incorporation and metabolism of ganglioside GM2 in skin fibroblasts from normal and GM2 gangliosidosis subjects. Eur J Biochem 149:247-255
    • (1985) Eur J Biochem , vol.149 , pp. 247-255
    • Sonderfeld, S.1    Conzelmann, E.2    Schwarzmann, G.3    Burg, J.4    Hinrichs, U.5    Sandhoff, K.6
  • 81
    • 0029743653 scopus 로고    scopus 로고
    • Ganglioside GM3 inhibition of EGF receptor mediated signal transduction
    • Rebbaa A, Hurh J, Yamamoto H, Kersey DS, Bremer EG (1996) Ganglioside GM3 inhibition of EGF receptor mediated signal transduction. Glycobiology 6:399-406
    • (1996) Glycobiology , vol.6 , pp. 399-406
    • Rebbaa, A.1    Hurh, J.2    Yamamoto, H.3    Kersey, D.S.4    Bremer, E.G.5
  • 82
    • 0030774126 scopus 로고    scopus 로고
    • Synthesis of ganglioside GM1 containing a thioglycosidic bond to its labeled ceramide(s). A facile synthesis starting from natural gangliosides
    • Schwarzmann G, Hofmann P, Pütz U (1997) Synthesis of ganglioside GM1 containing a thioglycosidic bond to its labeled ceramide(s). A facile synthesis starting from natural gangliosides. Carbohydr Res 304:43-52
    • (1997) Carbohydr Res , vol.304 , pp. 43-52
    • Schwarzmann, G.1    Hofmann, P.2    Pütz, U.3
  • 83
    • 0017851148 scopus 로고
    • A simple and novel method for tritium labeling of gangliosides and other sphingolipids
    • Schwarzmann G (1978) A simple and novel method for tritium labeling of gangliosides and other sphingolipids. Biochim Biophys Acta 529:106-114
    • (1978) Biochim Biophys Acta , vol.529 , pp. 106-114
    • Schwarzmann, G.1
  • 85
    • 0000135928 scopus 로고
    • Metabolism of exogenous gangliosides in cultured fibroblasts and cerebellar cells
    • Freysz L, Dreyfus H, Massarelli R, Gatt S, eds. Plenum Press, New York
    • Schwarzmann G, Hinrichs U, Sonderfeld S, Marsh D, Sandhoff K (1986) Metabolism of exogenous gangliosides in cultured fibroblasts and cerebellar cells, in Enzymes of Lipid Metabolism II, vol 116 (Freysz L, Dreyfus H, Massarelli R, Gatt S, eds) pp. 553-562. Plenum Press, New York
    • (1986) Enzymes of Lipid Metabolism II , vol.116 , pp. 553-562
    • Schwarzmann, G.1    Hinrichs, U.2    Sonderfeld, S.3    Marsh, D.4    Sandhoff, K.5
  • 86
    • 0025543251 scopus 로고
    • Patterns of endogenous gangliosides and metabolic processing of exogenous gangliosides in cerebellar granule cells during differentiation in culture
    • Riboni L, Prinetti A, Pitto M, Tettamanti G (1990) Patterns of endogenous gangliosides and metabolic processing of exogenous gangliosides in cerebellar granule cells during differentiation in culture. Neurochem Res 15:1175-1183
    • (1990) Neurochem Res , vol.15 , pp. 1175-1183
    • Riboni, L.1    Prinetti, A.2    Pitto, M.3    Tettamanti, G.4
  • 88
    • 0032718367 scopus 로고    scopus 로고
    • Estimating sphingolipid metabolism and trafficking in cultured cells using radiolabeled compounds
    • Riboni L, Viani P, Tettamanti G (2000) Estimating sphingolipid metabolism and trafficking in cultured cells using radiolabeled compounds. Methods Enzymol 311:656-682
    • (2000) Methods Enzymol , vol.311 , pp. 656-682
    • Riboni, L.1    Viani, P.2    Tettamanti, G.3
  • 89
    • 0023428445 scopus 로고
    • The sialic acid residue of exogenous GM1 ganglioside is recycled for biosynthesis of sialoglycoconjugates in rat liver
    • Ghidoni R, Trinchera M, Sonnino S, Chigorno V, Tettamanti G (1987) The sialic acid residue of exogenous GM1 ganglioside is recycled for biosynthesis of sialoglycoconjugates in rat liver. Biochem J 247:157-164
    • (1987) Biochem J , vol.247 , pp. 157-164
    • Ghidoni, R.1    Trinchera, M.2    Sonnino, S.3    Chigorno, V.4    Tettamanti, G.5
  • 90
    • 0027154901 scopus 로고
    • Metabolism of exogenous ganglioside GM1 in cultured cerebellar granule cells. The fatty acid and sphingosine moieties formed during degradation are re-used for lipid biosynthesis
    • Riboni L, Bassi R, Conti M, Tettamanti G (1993) Metabolism of exogenous ganglioside GM1 in cultured cerebellar granule cells. The fatty acid and sphingosine moieties formed during degradation are re-used for lipid biosynthesis. FEBS Lett 322:257-260
    • (1993) FEBS Lett , vol.322 , pp. 257-260
    • Riboni, L.1    Bassi, R.2    Conti, M.3    Tettamanti, G.4
  • 91
    • 0025164834 scopus 로고
    • The N-acetylgalactosamine residue of exogenous GM2 ganglioside is recycled for glycoconjugate biosynthesis in rat liver
    • Trinchera M, Ghidoni R, Greggia L, Tettamanti G (1990) The N-acetylgalactosamine residue of exogenous GM2 ganglioside is recycled for glycoconjugate biosynthesis in rat liver. Biochem J 266:103-106
    • (1990) Biochem J , vol.266 , pp. 103-106
    • Trinchera, M.1    Ghidoni, R.2    Greggia, L.3    Tettamanti, G.4
  • 92
    • 0031574237 scopus 로고    scopus 로고
    • Metabolic processing of gangliosides by human fibroblasts in culture-formation and recycling of separate pools of sphingosine
    • Chigorno V, Riva C, Valsecchi M, Nicolini M, Brocca P, Sonnino S (1997) Metabolic processing of gangliosides by human fibroblasts in culture-formation and recycling of separate pools of sphingosine. Eur J Biochem 250:661-669
    • (1997) Eur J Biochem , vol.250 , pp. 661-669
    • Chigorno, V.1    Riva, C.2    Valsecchi, M.3    Nicolini, M.4    Brocca, P.5    Sonnino, S.6
  • 93
    • 0023161242 scopus 로고
    • Enzymatic diagnosis of sphingolipidosis
    • Suzuki K (1987) Enzymatic diagnosis of sphingolipidosis. Methods Enzymol 138:727-762
    • (1987) Methods Enzymol , vol.138 , pp. 727-762
    • Suzuki, K.1
  • 94
    • 0023161249 scopus 로고
    • Activator proteins for lysosomal glycolipid hydrolysis
    • Conzelmann E, Sandhoff K (1987) Activator proteins for lysosomal glycolipid hydrolysis. Methods Enzymol 138:792-815
    • (1987) Methods Enzymol , vol.138 , pp. 792-815
    • Conzelmann, E.1    Sandhoff, K.2
  • 95
    • 0025816333 scopus 로고
    • Uptake and metabolism of radiolabelled GM1-ganglioside in skin fibroblasts from controls and patients with GM1-gangliosidosis
    • Midorikawa M, Inui K, Okada S, Yabuuchi H, Ogura K, Handa S (1991) Uptake and metabolism of radiolabelled GM1-ganglioside in skin fibroblasts from controls and patients with GM1-gangliosidosis. J Inherit Metab Dis 14:721-729
    • (1991) J Inherit Metab Dis , vol.14 , pp. 721-729
    • Midorikawa, M.1    Inui, K.2    Okada, S.3    Yabuuchi, H.4    Ogura, K.5    Handa, S.6
  • 96
    • 0023040518 scopus 로고
    • Incorporation and degradation of GM1 ganglioside and asialoGM1 ganglioside in cultured fibroblasts from normal individuals and patients with beta-galactosidase deficiency
    • Kobayashi T, Shinnoh N, Kuroiwa Y (1986) Incorporation and degradation of GM1 ganglioside and asialoGM1 ganglioside in cultured fibroblasts from normal individuals and patients with beta-galactosidase deficiency. Biochim Biophys Acta 875:115-121
    • (1986) Biochim Biophys Acta , vol.875 , pp. 115-121
    • Kobayashi, T.1    Shinnoh, N.2    Kuroiwa, Y.3
  • 97
    • 0026616919 scopus 로고
    • Metabolism of GM1 ganglioside in cultured skin fibroblasts: Anomalies in gangliosidoses, sialidoses, and sphingolipid activator protein (SAP, saposin) 1 and prosaposin deficient disorders
    • Schmid B, Paton BC, Sandhoff K, Harzer K (1992) Metabolism of GM1 ganglioside in cultured skin fibroblasts: Anomalies in gangliosidoses, sialidoses, and sphingolipid activator protein (SAP, saposin) 1 and prosaposin deficient disorders. Hum Genet 89:513-518
    • (1992) Hum Genet , vol.89 , pp. 513-518
    • Schmid, B.1    Paton, B.C.2    Sandhoff, K.3    Harzer, K.4


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