Cytochrome P450 3A expression in the human fetal liver: Evidence that CYP3A5 is expressed in only a limited number of fetal livers

Biology of the Neonate

Volumn 80, Issue 3, 2001, Pages 193-201

  Hakkola, Jukka ^a   Raunio, Hannu ^a   Purkunen, Raija ^b   Saarikoski, Seppo ^c   Vähäkangas, Kirsi ^a   Pelkonen, Olavi ^a   Edwards, Robert J ^e   Boobis, Alan R ^e   Pasanen, Markku ^a,d  

^a UNIVERSITY OF OULU   (Finland)

^b NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^c UNIVERSITY OF EASTERN FINLAND   (Finland)

^d NATIONAL AGENCY FOR MEDICINES   (Finland)

^e HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

Cytochrome P450; Drug metabolism; Fetus; Liver

Indexed keywords

CYTOCHROME P450; CYTOCHROME P450 3A4; CYTOCHROME P450 3A5; CYTOCHROME P450 3A7; MESSENGER RNA; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CONTROLLED STUDY; FETUS; FETUS LIVER; GESTATIONAL AGE; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOREACTIVITY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ARYL HYDROCARBON HYDROXYLASES; CLONING, MOLECULAR; CYTOCHROME P-450 CYP3A; CYTOCHROME P-450 ENZYME SYSTEM; GENE EXPRESSION; GESTATIONAL AGE; HUMANS; IMMUNOBLOTTING; ISOENZYMES; LIVER; MIXED FUNCTION OXYGENASES; OXIDOREDUCTASES, N-DEMETHYLATING; POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

STAPHYLOCOCCUS PHAGE 3A;

EID: 0035742772     PISSN: 00063126     EISSN: None     Source Type: Journal    
DOI: 10.1159/000047142     Document Type: Article

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