-
1
-
-
0034090264
-
Hepatocellular carcinoma
-
(2000)
J Hepatol
, vol.32
, Issue.SUPPL.
, pp. 225-237
-
-
Okuda, K.1
-
5
-
-
0033954691
-
Researchers and regulators reflect on first gene therapy death
-
(2000)
Nat Med
, vol.6
, pp. 6
-
-
Hollon, T.1
-
6
-
-
0032937083
-
Complete cure of established murine hepatocellular carcinoma is achievable by repeated injections of retroviruses carrying the herpes simplex virus thymidine kinase gene
-
(1999)
Gene Ther
, vol.6
, pp. 525-533
-
-
Kuriyama, S.1
Masui, K.2
Kikukawa, M.3
Sakamoto, T.4
Nakatami, T.5
Nagao, S.6
Yamazaki, M.7
Yoshiji, H.8
Tsujinoue, H.9
Fukui, H.10
Yoshimatsu, T.11
Ikenaka, K.12
-
12
-
-
0034921716
-
Cationic liposome-mediated gene delivery to the liver and to hepatocellular carcinomas in mice
-
(2001)
Hum Gene Ther
, vol.12
, pp. 799-809
-
-
Mohr, L.1
Yoon, S.K.2
Eastman, S.J.3
Chu, Q.4
Scheule, R.K.5
Sacglioni, P.P.6
Geissler, M.7
Heintges, T.8
Blum, H.E.9
Wands, J.R.10
-
13
-
-
17744376555
-
HVJ-liposome-mediated transfection of HSVtk gene driven by AFP promoter inhibits hepatic tumor growth of hepatocellular carcinoma in SCID mice
-
(2001)
Gene Ther
, vol.8
, pp. 80-83
-
-
Hirano, T.1
Kaneki, S.2
Kaneda, Y.3
Saito, I.4
Tamaoki, T.5
Furuyama, J.6
Tamaoki, T.7
Kobayashi, K.8
Ueki, T.9
Fujimoto, J.10
-
14
-
-
0035110705
-
Electro-poration-mediated interleukin-12 gene therapy for hepatocellular carcinoma in the mice model
-
(2001)
Cancer Res
, vol.61
, pp. 1005-1012
-
-
Yamashita, Y.I.1
Shimada, M.2
Hasegawa, H.3
Minagawa, R.4
Rikimaru, T.5
Hamatsu, T.6
Tanaka, S.7
Shirabe, K.8
Miyazaki, J.I.9
Sugimachi, K.10
-
25
-
-
0029908175
-
Evaluation of prodrugs ability to induce effective ablation of cells transduced with viral thymidine kinase gene
-
(1996)
Anticancer Res
, vol.16
, pp. 2623-2628
-
-
Kuriyama, S.1
Nakatani, T.2
Masui, K.3
Sakamoto, T.4
Tominaga, K.5
Yoshikawa, M.6
Fufui, H.7
Ikenaka, K.8
Tsujui, T.9
-
27
-
-
1642586736
-
Transduction efficacy, antitumoral effect and toxicity of adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir therapy of hepatocellular carcinoma: The woodchuck animal model
-
(2000)
Cancer Gene Ther
, vol.7
, pp. 657-662
-
-
Bilbao, R.1
Gerolami, R.2
Bralet, M.P.3
Qian, C.4
Tran, P.L.5
Tennant, B.6
Prieto, J.7
Brechot, C.8
-
28
-
-
0034652614
-
Evaluation of HSV-tk gene therapy in a rat model of chemically induced hepatocellular carcinoma by intratumoral and intrahepatic artery routes
-
(2000)
Cancer Res
, vol.60
, pp. 993-1001
-
-
Gerolami, R.1
Cardoso, J.2
Lewin, M.3
Bralet, M.P.4
Sa Cunha, A.5
Clement, O.6
Brechot, C.7
Tran, P.L.8
-
29
-
-
0032747138
-
Enzyme prodrug gene therapy: Synergistic use of the herpes simplex virus-cellular thymidine kinase/ganciclovir system and thymidylate synthase inhibitors for the treatment of colon cancer
-
(1999)
Cancer Res
, vol.59
, pp. 5233-5238
-
-
Wildner, O.1
Blaese, R.M.2
Candotti, F.3
-
30
-
-
0034085228
-
Two-drug combinations that increase apoptosis and modulate bak and bcl-X(L) expression in human colon tumor cell lines transduced with herpes simplex virus thymidine kinase
-
(2000)
Cancer Gene Ther
, vol.7
, pp. 563-573
-
-
McMasters, R.A.1
Wilbert, T.N.2
Jones, K.E.3
Pitlyk, K.4
Saylors, R.L.5
Moyer, M.P.6
Chambers, T.C.7
Drake, R.R.8
-
32
-
-
0033253012
-
Prodrug activation gene therapy and external beam irradiation in the treatment of prostate cancer
-
(1999)
Urology
, vol.54
, pp. 1098-1104
-
-
Atkinson, G.1
Hall, S.J.2
-
34
-
-
17344365922
-
Adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir gene therapy in patients with localized malignancy: Results of a phase I clinical trial in malignant mesothelioma
-
(1998)
Hum Gene Ther
, vol.9
, pp. 1083-1092
-
-
Sterman, D.H.1
Treat, J.2
Litzky, L.A.3
Amin, K.M.4
Coonrod, L.5
Molnar-Kimber, K.6
Recio, A.7
Knox, L.8
Wilson, J.M.9
Albelda, S.M.10
Kaiser, L.R.11
-
35
-
-
0034329438
-
Thymidine kinase gene therapy for human malignant glioma, using replication-deficient retroviruses or adenoviruses
-
(2000)
Hum Gene Ther
, vol.11
, pp. 2197-2205
-
-
Sandmair, A.M.1
Loimas, S.2
Puranen, P.3
Immonen, A.4
Kossila, M.5
Puranen, M.6
Hurskainen, H.7
Tyynela, K.8
Turunen, M.9
Vanninen, R.10
Lehtolainen, P.11
Paljarvi, L.12
Johansson, R.13
Vapalahti, M.14
Yla-Herttuala, S.15
-
36
-
-
0033135221
-
In situ gene therapy for adenocarcinoma of the prostate: A phase I clinical trial
-
(1999)
Hum Gene Ther
, vol.10
, pp. 1239-1249
-
-
Herman, J.R.1
Adler, H.L.2
Aguilar-Cordova, E.3
Rojas-Martinez, A.4
Woo, S.5
Timme, T.L.6
Wheeler, T.M.7
Thompson, T.C.8
Scardino, P.T.9
-
37
-
-
2442721450
-
A phase I/II dose-escalation study of herpes simplex virus type 1 thymidine kinase 'suicide' gene therapy for metastatic melanoma
-
Study Group on Gene Therapy of Metastatic Melanoma
-
(1998)
Hum Gene Ther
, vol.9
, pp. 2585-2594
-
-
Klatzmann, D.1
Cherin, P.2
Bensimon, G.3
Boyer, O.4
Coutellier, A.5
Charlotte, F.6
Boccaccio, C.7
Salzmann, J.L.8
Herson, S.9
-
42
-
-
16144363507
-
Lymphocyte apoptosis induced by CD95 (APO-1/FAS) ligand-expressing tumor cells - A mechanisms of immune evasion?
-
(1996)
Nat Med
, vol.2
, pp. 1361-1370
-
-
Strand, S.1
Hofmann, W.J.2
Hug, H.3
Müller, M.4
Otto, G.5
Strand, D.6
Mariani, S.M.7
Stremmel, W.8
Krammer, P.H.9
Galle, P.R.10
-
44
-
-
0033965355
-
Gene transfer to liver cancer cells of B7-1 plus interleukin-12 changes immunoeffector mechanisms and suppresses helper T cell type 1 cytokine production induced by interleukin 12 alone
-
(2000)
Hum Gene Ther
, vol.11
, pp. 127-138
-
-
Sun, Y.1
Qian, C.2
Peng, D.3
Prieto, J.4
-
46
-
-
0035197719
-
Gene therapy of orthotopic hepatocellular carcinoma in rats using adenovirus, coding for interleukin 12
-
(2001)
Hepatology
, vol.33
, pp. 52-61
-
-
Barajas, M.1
Mazzolini, G.2
Genove, G.3
Bilbao, R.4
Narvaiza, I.5
Schmitz, V.6
Sangro, B.7
Melero, I.8
Qian, C.9
Prieto, J.10
-
49
-
-
0035925568
-
Large nontransplanted hepatocellular carcinoma in woodchucks: Treatment with adenovirus-mediated delivery of interleukin 12/B7.1 genes
-
(2001)
J Natl Cancer Inst
, vol.93
, pp. 472-479
-
-
Putzer, B.M.1
Stiewe, T.2
Rodicker, F.3
Schildgen, O.4
Ruhm, S.5
Dirsch, O.6
Fiedler, M.7
Damen, U.8
Tennant, B.9
Scherer, C.10
Graham, F.L.11
Roggendorf, M.12
-
50
-
-
0027078670
-
Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4
-
(1992)
Cell
, vol.71
, pp. 1093-1102
-
-
Chen, L.1
Ashe, S.2
Brady, W.A.3
Hellstrom, I.4
Hellstrom, K.E.5
Ledbetter, J.A.6
McGowan, P.7
Linsley, P.S.8
-
51
-
-
0032765660
-
B7-1 (CD80)-gene transfer combined with interleukin-12 administration elicits protective and therapeutic immunity against mouse hepatocellular carcinoma
-
(1999)
Hepatology
, vol.30
, pp. 422-429
-
-
Tatsumi, T.1
Takehara, T.2
Kanto, T.3
Kuzushita, N.4
Ito, A.5
Kasahara, A.6
Sasaki, Y.7
Hori, M.8
Hayashi, N.9
-
54
-
-
0034596475
-
Adoptive immunotherapy to lower postsurgical recurrence rates of hepatocellular carcinoma: A randomised trial
-
(2000)
Lancet
, vol.356
, pp. 802-807
-
-
Takayama, T.1
Sekine, T.2
Makuuchi, M.3
Yamasaki, S.4
Kosuge, T.5
Yamamoto, J.6
Shimada, K.7
Sakamoto, M.8
Hirohashi, S.9
Ohashi, Y.10
Kakizoe, T.11
-
55
-
-
0033971393
-
Adenoviral gene transfer of IL-12 into tumors synergizes with adoptive T-cell therapy both at the induction and the effector level
-
(2000)
Hum Gene Ther
, vol.11
, pp. 113-125
-
-
Mazzolini, G.1
Qian, C.2
Narvaiza, I.3
Barajas, M.4
Borras-Cuesta, F.5
Xie, X.6
Duarte, M.7
Melero, I.8
Prieto, J.9
-
59
-
-
0032844949
-
Intratumoral injection of bone-marrow derived dendritic cells engineered to produce interleukin-12 induces complete regression of established murine transplantable colon adenocarcinomas
-
(1999)
Gene Ther
, vol.6
, pp. 1779-1784
-
-
Melero, I.1
Duarte, M.2
Ruiz, J.3
Sangro, B.4
Galofre, J.C.5
Mazzolini, G.6
Bustos, M.7
Qian, C.8
Prieto, J.9
-
61
-
-
0345104277
-
Alpha-fetoprotein-specific genetic immunotherapy for hepatocellular carcinoma
-
(1999)
Cancer Res
, vol.59
, pp. 3064-3067
-
-
Vollmer, C.M.1
Eilber, F.C.2
Butterfield, L.H.3
Ribas, A.4
Dissette, V.B.5
Koh, A.6
Montejo, L.D.7
Lee, M.C.8
Andrews, K.J.9
McBride, W.H.10
Glaspy, J.A.11
Economou, J.S.12
-
66
-
-
14444267312
-
p53 gene therapy in a rat model of hepatocellular carcinoma: Intra-arterial delivery of a recombinant adenovirus
-
(1998)
Clin Cancer Res
, vol.4
, pp. 149-1659
-
-
Anderson, S.C.1
Johnson, D.E.2
Harris, M.P.3
Engler, H.4
Hancock, W.5
Huang, W.M.6
Wilis, K.N.7
Gregory, R.J.8
Sutjipto, S.9
Wen, S.F.10
Lofgren, S.11
Shepard, H.M.12
Maneval, D.C.13
-
68
-
-
0034650673
-
In vivo electropo-retic transfer of bcl-2 antisense oligonucleotide inhibits the development of hepatocellular carcinoma in rats
-
(2000)
Int J Cancer
, vol.85
, pp. 260-266
-
-
Baba, M.1
Iishi, H.2
Tatsuta, M.3
-
69
-
-
0034891659
-
Transfer of bcl-xs plasmid is effective in preventing and inhibiting rat hepatocellular carcinoma induced by N-nitrosomorpholine
-
(2001)
Gene Ther
, vol.8
, pp. 1149-1156
-
-
Baba, M.1
Iishi, H.2
Tatsuta, M.3
-
70
-
-
0035874885
-
Transduction of antisense cyclin D1 using two-step gene transfer inhibits the growth of rat hepatoma cells
-
(2001)
Cancer Res
, vol.61
, pp. 47779-4783
-
-
Uto, H.1
Ido, A.2
Moriuchi, A.3
Onaga, Y.4
Nagata, K.5
Onaga, M.6
Tahara, Y.7
Hori, T.8
Hirono, S.9
Hayashi, K.10
Tsubouchi, H.11
-
71
-
-
0034816673
-
Target gene therapy for alpha-fetoprotein-producing hepatocellular carcinoma by E1B55k-attenuated adenovirus
-
(2001)
Biochem Biophys Res Commun
, vol.282
, pp. 529-535
-
-
Ohashi, M.1
Kanai, F.2
Tateishi, K.3
Taniguchi, H.4
Marignani, P.A.5
Yoshida, Y.6
Shiratori, Y.7
Hamada, H.8
Omata, M.9
-
72
-
-
0030053042
-
Preliminary report: The short-term effects of direct p53 DNA injection in primary hepatocellular carcinomas
-
(1996)
Cancer Detect Prev
, vol.20
, pp. 103-107
-
-
Habib, N.A.1
Ding, S.F.2
El-Masry, R.3
Mitry, R.R.4
Honda, K.5
Michail, N.E.6
Dalla Serra, G.7
Greco, L.8
Bassyouni, M.9
El-Tohkhy, M.10
Abdel-Gaffar, Y.11
-
73
-
-
0008792263
-
Intra-arterial p53 gene therapy of liver malignancies: Preclinical studies and initial clinical observations
-
(1997)
Cancer Gene Ther
, vol.4
-
-
Horowitz, J.A.1
Maneval, D.C.2
Ryback, M.E.3
Johnson, D.4
Harris, M.P.5
Demers, W.G.6
Anderson, S.7
Venook, A.8
Warren, R.9
-
74
-
-
0035835373
-
E1B-deleted adenovirus (dl520) gene therapy for patients with primary and secondary liver tumors
-
(2001)
Hum Gene Ther
, vol.12
, pp. 219-226
-
-
Habib, N.A.1
Sarraf, C.E.2
Mitry, R.R.3
Havlik, R.4
Nichols, J.5
Kelly, M.6
Vernon, C.C.7
Gueret-Wardle, D.8
El-Masry, R.9
Salama, H.10
Ahmed, R.11
Michail, N.E.12
Edward, E.13
Jensen, S.L.14
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